Physiobiological results of ultraviolet radiation and its functions in skin carcinogenesis

• Autor(a) principal: Frazão, Luiz Felipe Neves
• Data de Publicação: 2024
• Outros Autores: Cruvinel, Laura Marques, Silva, Ana Luísa Pereira da, Silva, Gustavo Hipólito, Juntolli, Ana Carolina Veras, Azevedo , Adriane Ferreira de, Naser , Maisam Shadi Riad Hilal, Piveta, Juliana Tiemi, Oliveira, Maria Eduarda Gibbon, Mota , Maria Clara Wanderley, Santos, Leonardo Portilho, Ferreira, Lucas Franco, Cabral, Matheus Costa, Zanoni, Rodrigo Daniel
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/1101
• topic: Câncer; pele; radiação.; Cancer; Skin; Radiation.; Cáncer; Piel; Radiación.

The aim of this study is to expose the effects that solar radiation causes to the human body and identify its role in skin carcinogenesis. This is a narrative review, where a search for articles was carried out in the Medical Literature Analysis and Retrievel System Online (MEDLINE) and Scientific Electronic Library Online (SciELO) databases, with the following Health Sciences Descriptors (DeCS): Cancer; Skin; Radiation; combined with each other using the Boolean operators "AND" and "OR". Selecting articles between the periods of 2011 and 2022, in English, Portuguese and Spanish, to increase the level of relevance and quality of the review, in addition to the technical-scientific basis coming from literary works renowned in history. In relation to skin cancer , UV radiation plays a complete role in oncogenesis, after all it modifies the physiobiological functions of cells and their architecture. Changes in the DNA of cells, the frequency and amount of sun exposure, are the factors that lead to cancer over time, especially in regions with greater exposure. Therefore, there is a need to change lifestyle habits, such as using chemical sunscreens and thick clothing, increasing skin protection. In addition to raising awareness among the population about the warning signs of the tumor and its characteristics, so that early access to health units and therapy can minimize its effects. Scientific research should also be encouraged, after all, cancer continues to be a disease that needs to be radicalized.