Perspectives on Therapies for Parkinson's Disease: Investigating Neuroprotectors and Progression Modifiers

• Autor(a) principal: Vasconcelos, José Lucas Moura
• Data de Publicação: 2024
• Outros Autores: Leite , Andressa Karoline Alves, Teixeira, Anisia da Silva, Barreto , Bárbara Dayann Rocha, Pinaty , Carla Maria Zanelli, Henrique , Caroline Fernanda Alexandre, Dall'Agnol, Dhemer Jhony, Brito , Giovanna Vieira, Viana , Giovana Pereira, Bonatti , Heloísa Maria Marson, Capatto , Julia Maria Prestes, Gonçalves , Kauara Marcelino, Rodrigues , Larissa Cunha Hipolito, Godinho , Luana Cruz Nunes, Lima , Maria Eugênia Abílio, Costa , Maria Fernanda Monteiro, Cruz , Mariana Horn da, Cardoso , Radhija Albuquerque Rocha, Guimarães , Renata Gomes Santos, Bomfim, Samuel Antunes Correia, Silva , Thiago Matheus Ribeiro Da
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/1368
• topic: Doença de Parkinson; Parkinson's disease

This review addressed advances in the development of neuroprotective and progression-modifying therapies in Parkinson's disease (PD). Literature analysis highlighted the potential of therapeutic strategies based on antioxidants, gene therapy, and other innovative approaches to slow down PD progression. The results of reviewed studies suggest that these therapies show significant promise in reducing motor symptoms and preserving dopaminergic function. However, challenges such as PD heterogeneity and lack of robust biomarkers remain significant obstacles to translating these findings into effective therapies. Ongoing research and interdisciplinary collaboration are essential to drive innovation and transform these promising therapeutic perspectives into clinical reality.