EXHALED AND PLASMA NITRITE: a comparative study among healthy, cirrhotic and liver transplant patients

Detalhes bibliográficos
Autor(a) principal: AUGUSTO,Viviane S
Data de Publicação: 2014
Outros Autores: RODRIGUES,Alfredo J, C SILVEIRA,Ana Paula, CASTRO E SILVA Jr,Orlando de, MENTE,Enio David, EVORA,Paulo Roberto B
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos de gastroenterologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032014000100016
Resumo: Context There is a relative lack of studies about exhaled nitrite (NO2-) concentrations in cirrhotic and transplanted patients. Objective Verify possible differences and correlations between the levels of NO2-, measured in plasma and exhaled breath condensate collected from patients with cirrhosis and liver transplant. Method Sixty adult male patients, aged between 27 and 67 years, were subdivided into three groups: a control group comprised of 15 healthy volunteers, a cirrhosis group composed of 15 volunteers, and a transplant group comprised of 30 volunteers. The NO2- concentrations were measured by chemiluminescence. Results 1) The analysis of plasma NO2- held among the three groups showed no statistical significance. 2) The comparison between cirrhotic and control groups, control and transplanted and cirrhotic and transplanted was not statistically significant. 3) The measurements performed on of NO2- exhaled breath condensate among the three groups showed no statistical difference. 4) When comparing the control group samples and cirrhotic, control and transplanted and cirrhotic and transplanted, there was no significant changes in the concentrations of NO2-. Conclusion No correlations were found between plasma and exhaled NO2-, suggesting that the exhaled NO2- is more reflective of local respiratory NO release than the systemic circulation.
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spelling EXHALED AND PLASMA NITRITE: a comparative study among healthy, cirrhotic and liver transplant patientsLiver transplantationLiver cirrhosisNitric oxide, diagnostic use. Context There is a relative lack of studies about exhaled nitrite (NO2-) concentrations in cirrhotic and transplanted patients. Objective Verify possible differences and correlations between the levels of NO2-, measured in plasma and exhaled breath condensate collected from patients with cirrhosis and liver transplant. Method Sixty adult male patients, aged between 27 and 67 years, were subdivided into three groups: a control group comprised of 15 healthy volunteers, a cirrhosis group composed of 15 volunteers, and a transplant group comprised of 30 volunteers. The NO2- concentrations were measured by chemiluminescence. Results 1) The analysis of plasma NO2- held among the three groups showed no statistical significance. 2) The comparison between cirrhotic and control groups, control and transplanted and cirrhotic and transplanted was not statistically significant. 3) The measurements performed on of NO2- exhaled breath condensate among the three groups showed no statistical difference. 4) When comparing the control group samples and cirrhotic, control and transplanted and cirrhotic and transplanted, there was no significant changes in the concentrations of NO2-. Conclusion No correlations were found between plasma and exhaled NO2-, suggesting that the exhaled NO2- is more reflective of local respiratory NO release than the systemic circulation. Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia e Outras Especialidades - IBEPEGE. 2014-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032014000100016Arquivos de Gastroenterologia v.51 n.1 2014reponame:Arquivos de gastroenterologia (Online)instname:Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologiainstacron:IBEPEGE10.1590/S0004-28032014000100004info:eu-repo/semantics/openAccessAUGUSTO,Viviane SRODRIGUES,Alfredo JC SILVEIRA,Ana PaulaCASTRO E SILVA Jr,Orlando deMENTE,Enio DavidEVORA,Paulo Roberto Beng2014-11-24T00:00:00Zoai:scielo:S0004-28032014000100016Revistahttp://www.scielo.br/aghttps://old.scielo.br/oai/scielo-oai.php||secretariaarqgastr@hospitaligesp.com.br1678-42190004-2803opendoar:2014-11-24T00:00Arquivos de gastroenterologia (Online) - Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologiafalse
dc.title.none.fl_str_mv EXHALED AND PLASMA NITRITE: a comparative study among healthy, cirrhotic and liver transplant patients
title EXHALED AND PLASMA NITRITE: a comparative study among healthy, cirrhotic and liver transplant patients
spellingShingle EXHALED AND PLASMA NITRITE: a comparative study among healthy, cirrhotic and liver transplant patients
AUGUSTO,Viviane S
Liver transplantation
Liver cirrhosis
Nitric oxide, diagnostic use.
title_short EXHALED AND PLASMA NITRITE: a comparative study among healthy, cirrhotic and liver transplant patients
title_full EXHALED AND PLASMA NITRITE: a comparative study among healthy, cirrhotic and liver transplant patients
title_fullStr EXHALED AND PLASMA NITRITE: a comparative study among healthy, cirrhotic and liver transplant patients
title_full_unstemmed EXHALED AND PLASMA NITRITE: a comparative study among healthy, cirrhotic and liver transplant patients
title_sort EXHALED AND PLASMA NITRITE: a comparative study among healthy, cirrhotic and liver transplant patients
author AUGUSTO,Viviane S
author_facet AUGUSTO,Viviane S
RODRIGUES,Alfredo J
C SILVEIRA,Ana Paula
CASTRO E SILVA Jr,Orlando de
MENTE,Enio David
EVORA,Paulo Roberto B
author_role author
author2 RODRIGUES,Alfredo J
C SILVEIRA,Ana Paula
CASTRO E SILVA Jr,Orlando de
MENTE,Enio David
EVORA,Paulo Roberto B
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv AUGUSTO,Viviane S
RODRIGUES,Alfredo J
C SILVEIRA,Ana Paula
CASTRO E SILVA Jr,Orlando de
MENTE,Enio David
EVORA,Paulo Roberto B
dc.subject.por.fl_str_mv Liver transplantation
Liver cirrhosis
Nitric oxide, diagnostic use.
topic Liver transplantation
Liver cirrhosis
Nitric oxide, diagnostic use.
description Context There is a relative lack of studies about exhaled nitrite (NO2-) concentrations in cirrhotic and transplanted patients. Objective Verify possible differences and correlations between the levels of NO2-, measured in plasma and exhaled breath condensate collected from patients with cirrhosis and liver transplant. Method Sixty adult male patients, aged between 27 and 67 years, were subdivided into three groups: a control group comprised of 15 healthy volunteers, a cirrhosis group composed of 15 volunteers, and a transplant group comprised of 30 volunteers. The NO2- concentrations were measured by chemiluminescence. Results 1) The analysis of plasma NO2- held among the three groups showed no statistical significance. 2) The comparison between cirrhotic and control groups, control and transplanted and cirrhotic and transplanted was not statistically significant. 3) The measurements performed on of NO2- exhaled breath condensate among the three groups showed no statistical difference. 4) When comparing the control group samples and cirrhotic, control and transplanted and cirrhotic and transplanted, there was no significant changes in the concentrations of NO2-. Conclusion No correlations were found between plasma and exhaled NO2-, suggesting that the exhaled NO2- is more reflective of local respiratory NO release than the systemic circulation.
publishDate 2014
dc.date.none.fl_str_mv 2014-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032014000100016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032014000100016
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-28032014000100004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia e Outras Especialidades - IBEPEGE.
publisher.none.fl_str_mv Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia e Outras Especialidades - IBEPEGE.
dc.source.none.fl_str_mv Arquivos de Gastroenterologia v.51 n.1 2014
reponame:Arquivos de gastroenterologia (Online)
instname:Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia
instacron:IBEPEGE
instname_str Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia
instacron_str IBEPEGE
institution IBEPEGE
reponame_str Arquivos de gastroenterologia (Online)
collection Arquivos de gastroenterologia (Online)
repository.name.fl_str_mv Arquivos de gastroenterologia (Online) - Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia
repository.mail.fl_str_mv ||secretariaarqgastr@hospitaligesp.com.br
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