Tuberculosis treatment outcomes in HIV coinfection cases in the Legal Amazon

Detalhes bibliográficos
Autor(a) principal: Mariano, Amanda Silveira
Data de Publicação: 2023
Outros Autores: Orfão, Nathalia Halax
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Baiana de Saúde Pública (Online)
Texto Completo: https://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/3748
Resumo: One of the great challenges for the control of tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection is the treatment, which, despite being available free of charge within the scope of the Brazilian National Health System, has low adherence rates and abandonment of treatment of both diseases for various reasons, for example, lack of a bond with health services, difficulty of ingestion of the multiple medications and their possible adverse reactions, among others, which consequently leads to unfavorable outcomes. In this sense, this article aimed to analyze the outcomes of TB treatment in people living with HIV in Rondônia, between 2008 and 2018. It is an ecological study with a quantitative approach, based on a survey of the clinical variables, municipality of residence and notification of cases of TB/HIV co-infection aged 18 years or over, residents of the state, and who did not have the variable “closure status” blank. Data were spatially analyzed in TabWin. Of the 721 selected cases, a low percentage of cure (50-84%) and a high percentage for abandonment (6-49%) were identified, with a mean time between diagnosis and treatment of nine days and treatment time of 158 days. Only 25 municipalities in the state reported cases of coinfection, although 34 were characterized as the municipality of residence. Thus, there is a centralization of notifications and difficulties in adherence and bonding strategies, such as the treatment directly observed, having repercussions on control actions and, consequently, on unfavorable outcomes for TB treatment in people living with HIV in Rondônia.
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spelling Tuberculosis treatment outcomes in HIV coinfection cases in the Legal AmazonResultados del tratamiento de tuberculosis en casos de coinfección por VIH en la Amazonia LegalDesfechos do tratamento de tuberculose nos casos de coinfecção por HIV na Amazônia LegalTuberculoseCoinfecçãoInfecções por HIVResultado do tratamentoTuberculosisCoinfectionHIV infectionsTreatment outcomeTuberculosisCoinfecciónInfecciones por VIHResultado del tratamientoOne of the great challenges for the control of tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection is the treatment, which, despite being available free of charge within the scope of the Brazilian National Health System, has low adherence rates and abandonment of treatment of both diseases for various reasons, for example, lack of a bond with health services, difficulty of ingestion of the multiple medications and their possible adverse reactions, among others, which consequently leads to unfavorable outcomes. In this sense, this article aimed to analyze the outcomes of TB treatment in people living with HIV in Rondônia, between 2008 and 2018. It is an ecological study with a quantitative approach, based on a survey of the clinical variables, municipality of residence and notification of cases of TB/HIV co-infection aged 18 years or over, residents of the state, and who did not have the variable “closure status” blank. Data were spatially analyzed in TabWin. Of the 721 selected cases, a low percentage of cure (50-84%) and a high percentage for abandonment (6-49%) were identified, with a mean time between diagnosis and treatment of nine days and treatment time of 158 days. Only 25 municipalities in the state reported cases of coinfection, although 34 were characterized as the municipality of residence. Thus, there is a centralization of notifications and difficulties in adherence and bonding strategies, such as the treatment directly observed, having repercussions on control actions and, consequently, on unfavorable outcomes for TB treatment in people living with HIV in Rondônia.Uno de los grandes desafíos para controlar la coinfección de tuberculosis (TB) y del virus de la inmunodeficiencia humana (VIH) es el tratamiento, que, a pesar de ser gratuito en el ámbito del Sistema Único de Salud, presenta bajas tasas de adherencia y abandono de ambas enfermedades, por diversas razones, ya sea por la falta de vinculación con los servicios de salud y múltiples medicamentos de difícil toma y sus posibles reacciones adversas, por ejemplo, que en consecuencia conducen a desenlaces desfavorables. En ese sentido, este estudio tuvo como objetivo analizar los resultados del tratamiento de la TB en personas que viven con el VIH en Rondônia (Brasil), en el periodo entre 2008 y 2018. Este es un estudio ecológico con enfoque cuantitativo, basado en la encuesta de variables clínicas, municipio de residencia y notificación de casos de infección por TB/VIH en pacientes de 18 años o más, residentes en el estado y que no tenían en blanco la variable “estado de cierre”. Los datos se analizaron espacialmente en TabWin. De los 721 casos seleccionados se identificó un bajo porcentaje de curación (50-84%) y un alto porcentaje de abandono (6-49%), con un tiempo promedio entre diagnóstico y tratamiento de nueve días y, por tratamiento, de 158 días. Solamente 25 municipios del estado reportaron casos de coinfección, aunque 34 se caracterizaron como municipios de residencia. Esto demuestra haber una centralización de las notificaciones y dificultades en las estrategias de adhesión y vinculación, como el tratamiento directamente observado, teniendo repercusiones en las acciones de control y, consecuentemente, en resultados desfavorables para el tratamiento de la TB en personas que viven con VIH en Rondônia.Um dos grandes desafios para o controle da coinfecção de tuberculose (TB) e do vírus da imunodeficiência humana (HIV) é o tratamento, que, apesar de ser disponibilizado gratuitamente no Sistema Único de Saúde, apresenta baixos índices de adesão, bem como abandono do tratamento de ambas as doenças por diversos motivos, por exemplo, ausência de vínculo com os serviços de saúde, difícil ingestão dos múltiplos medicamentos e suas possíveis reações adversas, entre outros, consequentemente levando a desfechos desfavoráveis. Nesse sentido, este artigo pretende analisar os desfechos do tratamento de TB em pessoas vivendo com HIV em Rondônia, entre 2008 e 2018. Trata-se de um estudo ecológico com abordagem quantitativa, a partir do levantamento das variáveis clínicas, município de residência e notificação dos casos de coinfecção TB/HIV, com idade igual ou superior a 18 anos, residentes do estado e que não apresentassem a variável “situação de encerramento” em branco. Os dados foram analisados espacialmente no TabWin. Dos 721 casos selecionados, identificou-se baixo percentual de cura (50-84%) e elevado de abandono (6-49%), com tempo médio entre diagnóstico e tratamento de nove dias e, de tratamento, de 158 dias. Somente 25 municípios do estado notificaram casos de coinfecção, embora 34 se caracterizassem como municípios de residência. Com isso, verificam-se centralização das notificações e dificuldades nas estratégias de adesão e vínculo, tal como o tratamento diretamente observado, repercutindo nas ações de controle e, consequentemente, nos desfechos desfavoráveis para o tratamento da TB em pessoas vivendo com HIV em Rondônia.SESAB2023-04-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/374810.22278/2318-2660.2022.v46.n4.a3748Revista Baiana de Saúde Pública; v. 46 n. 4 (2022); 117-1332318-26600100-023310.22278/2318-2660.2022.v46.N4reponame:Revista Baiana de Saúde Pública (Online)instname:Secretaria da Saúde do Estado da Bahia (Sesab)instacron:IBICTporhttps://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/3748/3181Copyright (c) 2023 Revista Baiana de Saúde Públicainfo:eu-repo/semantics/openAccessMariano, Amanda SilveiraOrfão, Nathalia Halax2023-05-08T13:25:58Zoai:ojs.pkp.sfu.ca:article/3748Revistahttps://rbsp.sesab.ba.gov.br/index.php/rbspPUBhttps://rbsp.sesab.ba.gov.br/index.php/rbsp/oai||saude.revista@saude.ba.gov.br|| rbsp.saude@saude.ba.gov.br2318-26600100-0233opendoar:2024-03-06T12:58:27.686971Revista Baiana de Saúde Pública (Online) - Secretaria da Saúde do Estado da Bahia (Sesab)false
dc.title.none.fl_str_mv Tuberculosis treatment outcomes in HIV coinfection cases in the Legal Amazon
Resultados del tratamiento de tuberculosis en casos de coinfección por VIH en la Amazonia Legal
Desfechos do tratamento de tuberculose nos casos de coinfecção por HIV na Amazônia Legal
title Tuberculosis treatment outcomes in HIV coinfection cases in the Legal Amazon
spellingShingle Tuberculosis treatment outcomes in HIV coinfection cases in the Legal Amazon
Mariano, Amanda Silveira
Tuberculose
Coinfecção
Infecções por HIV
Resultado do tratamento
Tuberculosis
Coinfection
HIV infections
Treatment outcome
Tuberculosis
Coinfección
Infecciones por VIH
Resultado del tratamiento
title_short Tuberculosis treatment outcomes in HIV coinfection cases in the Legal Amazon
title_full Tuberculosis treatment outcomes in HIV coinfection cases in the Legal Amazon
title_fullStr Tuberculosis treatment outcomes in HIV coinfection cases in the Legal Amazon
title_full_unstemmed Tuberculosis treatment outcomes in HIV coinfection cases in the Legal Amazon
title_sort Tuberculosis treatment outcomes in HIV coinfection cases in the Legal Amazon
author Mariano, Amanda Silveira
author_facet Mariano, Amanda Silveira
Orfão, Nathalia Halax
author_role author
author2 Orfão, Nathalia Halax
author2_role author
dc.contributor.author.fl_str_mv Mariano, Amanda Silveira
Orfão, Nathalia Halax
dc.subject.por.fl_str_mv Tuberculose
Coinfecção
Infecções por HIV
Resultado do tratamento
Tuberculosis
Coinfection
HIV infections
Treatment outcome
Tuberculosis
Coinfección
Infecciones por VIH
Resultado del tratamiento
topic Tuberculose
Coinfecção
Infecções por HIV
Resultado do tratamento
Tuberculosis
Coinfection
HIV infections
Treatment outcome
Tuberculosis
Coinfección
Infecciones por VIH
Resultado del tratamiento
description One of the great challenges for the control of tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection is the treatment, which, despite being available free of charge within the scope of the Brazilian National Health System, has low adherence rates and abandonment of treatment of both diseases for various reasons, for example, lack of a bond with health services, difficulty of ingestion of the multiple medications and their possible adverse reactions, among others, which consequently leads to unfavorable outcomes. In this sense, this article aimed to analyze the outcomes of TB treatment in people living with HIV in Rondônia, between 2008 and 2018. It is an ecological study with a quantitative approach, based on a survey of the clinical variables, municipality of residence and notification of cases of TB/HIV co-infection aged 18 years or over, residents of the state, and who did not have the variable “closure status” blank. Data were spatially analyzed in TabWin. Of the 721 selected cases, a low percentage of cure (50-84%) and a high percentage for abandonment (6-49%) were identified, with a mean time between diagnosis and treatment of nine days and treatment time of 158 days. Only 25 municipalities in the state reported cases of coinfection, although 34 were characterized as the municipality of residence. Thus, there is a centralization of notifications and difficulties in adherence and bonding strategies, such as the treatment directly observed, having repercussions on control actions and, consequently, on unfavorable outcomes for TB treatment in people living with HIV in Rondônia.
publishDate 2023
dc.date.none.fl_str_mv 2023-04-24
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dc.identifier.uri.fl_str_mv https://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/3748
10.22278/2318-2660.2022.v46.n4.a3748
url https://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/3748
identifier_str_mv 10.22278/2318-2660.2022.v46.n4.a3748
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://rbsp.sesab.ba.gov.br/index.php/rbsp/article/view/3748/3181
dc.rights.driver.fl_str_mv Copyright (c) 2023 Revista Baiana de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2023 Revista Baiana de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv SESAB
publisher.none.fl_str_mv SESAB
dc.source.none.fl_str_mv Revista Baiana de Saúde Pública; v. 46 n. 4 (2022); 117-133
2318-2660
0100-0233
10.22278/2318-2660.2022.v46.N4
reponame:Revista Baiana de Saúde Pública (Online)
instname:Secretaria da Saúde do Estado da Bahia (Sesab)
instacron:IBICT
instname_str Secretaria da Saúde do Estado da Bahia (Sesab)
instacron_str IBICT
institution IBICT
reponame_str Revista Baiana de Saúde Pública (Online)
collection Revista Baiana de Saúde Pública (Online)
repository.name.fl_str_mv Revista Baiana de Saúde Pública (Online) - Secretaria da Saúde do Estado da Bahia (Sesab)
repository.mail.fl_str_mv ||saude.revista@saude.ba.gov.br|| rbsp.saude@saude.ba.gov.br
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