Effects of different physical exercise intensities on the metabolism of rats subjected to fructose consumption

• Autor(a) principal: Corona, Luiz Felipe Petrusk
• Data de Publicação: 2022
• Outros Autores: Arraes, Alexandre Sousa, Ávila, Eudes Thiago Pereira, Valim, Jefferson Dias, Marques Junior, Jair, Habitante, Carlos Alexandre
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista brasileira de obesidade, nutrição e emagrecimento
• Texto Completo: https://www.rbone.com.br/index.php/rbone/article/view/1930
• topic: Physical exercise; Fructose; Insulin Resistance; Hyperglycemia; Lipid Metabolism; Ejercicio físico; Fructosa; Resistencia a la insulina; Hiperglucemia; Metabolismo de los lipidios; Esercizio fisico; Fruttosio; Resistenza all'insulina; Iperglicemia; Metabolismo lipidico; Exercício físico; Frutose; Resistência à insulina; Hiperglicemia; Metabolismo Lipídico; Exercício físico; Frutose; Resistência à insulina; Hiperglicemia; Metabolismo lipídico

Physical exercise can be used as a low-cost strategy to reduce pathologies such as obesity and diabetes. The aim of this study was to verify the effect of different intensities of physical exercise upon fructose consumption in male Wistar rats metabolism. The rats were distributed in six experimental groups: Sedentary Control (CS), Mild Exercise Control (CE2), Vigorous Exercise Control (CE6), Sedentary Fructose (FS), Fructose Mild Exercise (FE2) and Fructose Vigorous Exercise (FE6). Water-diluted fructose (20%) was administered for groups (F) whereas groups (E) were submitted to a 12 weeks aquatic training program. Mild physical exercise (E2) was performed five times a week (2% overload) for 60 minutes and vigorous exercise (E6) was performed three times a week (6% overload) for 15 minutes, splatted in three sets of five minutes, with one minute of passive rest or until the impossibility of continuity. The FS group displayed hyperglycemia; lower serum HDL concentration; higher total cholesterol, triglycerides and AST/ALT ratio; higher hepatic, retroperitoneal adipose (RET), and heart tissue weight. Vigorous physical exercise induced an increase in the relative weight of the gastrocnemius muscle (GAST) and augmented HDL levels; decreased RET and epididiaml weight; and lower glycemia. Mild exercise was more effective in the cholesterol control. Both treatments reversed triglyceridemia induced by fructose consumption. We observed that both mild and vigorous exercise had positive effects on comorbidities related to insulin resistance. It is suggested that a combination of intensities may promote better results