Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil

Detalhes bibliográficos
Autor(a) principal: Silvestre, Rodrigo Vellasco Duarte
Data de Publicação: 2009
Outros Autores: Leal, Mariana Ferreira, Demachki, Samia, Nahum, Márcia Cristina de Souza, Bernardes, Julio Guilherme Balieiro, Rabenhorst, Silvia Helena Barem, Smith, Marília de Arruda Cardoso, Mello, Wyller Alencar de, Guimarães, Adriana Costa, Burbano, Rommel Rodríguez
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: https://patua.iec.gov.br/handle/iec/934
Resumo: The presence of human papillomavirus (HPV) was evaluated in 65 samples of prostate tumours and six samples of prostates with benign prostatic hyperplasia from individuals from Northern Brazil. We used a highly sensitive test, the Linear Array HPV Genotyping Test, to detect 37 high and low-risk HPV types. In this study, only 3% of tumour samples showed HPV infection. Our findings support the conclusion that, despite the high incidence of HPV infection in the geographic regions studied, HPV was not associated with a higher risk of prostate cancer. To our knowledge, this is the first study evaluating the frequency of HPV detection in prostatic tissue of individuals from Brazil.
id IEC-2_035498ac191b98938892e1667a4bbbd1
oai_identifier_str oai:patua.iec.gov.br:iec/934
network_acronym_str IEC-2
network_name_str Repositório Digital do Instituto Evandro Chagas (Patuá)
repository_id_str
spelling Silvestre, Rodrigo Vellasco DuarteLeal, Mariana FerreiraDemachki, SamiaNahum, Márcia Cristina de SouzaBernardes, Julio Guilherme BalieiroRabenhorst, Silvia Helena BaremSmith, Marília de Arruda CardosoMello, Wyller Alencar deGuimarães, Adriana CostaBurbano, Rommel Rodríguez2016-01-26T11:39:48Z2016-01-26T11:39:48Z2009SILVESTRE, Rodrigo Vellasco Duarte et al. Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil. Memórias do Instituto Oswaldo Cruz, v. 104, n. 4, p. 665-667, 20090074-0276https://patua.iec.gov.br/handle/iec/934The presence of human papillomavirus (HPV) was evaluated in 65 samples of prostate tumours and six samples of prostates with benign prostatic hyperplasia from individuals from Northern Brazil. We used a highly sensitive test, the Linear Array HPV Genotyping Test, to detect 37 high and low-risk HPV types. In this study, only 3% of tumour samples showed HPV infection. Our findings support the conclusion that, despite the high incidence of HPV infection in the geographic regions studied, HPV was not associated with a higher risk of prostate cancer. To our knowledge, this is the first study evaluating the frequency of HPV detection in prostatic tissue of individuals from Brazil.Universidade Federal do Pará. Hospital Universitário João de Barros Barreto. Departamento de Anatomia Patológica. Belém, PA, Brasil.Universidade Federal de São Paulo. Departamento de Morfologia e Genética. Disciplina de Genética. São Paulo, SP. Brasil.Universidade Federal do Pará. Hospital Universitário João de Barros Barreto. Departamento de Anatomia Patológica. Belém, PA, Brasil.Universidade Federal do Pará. Hospital Universitário João de Barros Barreto. Departamento de Anatomia Patológica. Belém, PA, Brasil.Universidade Federal do Pará. Hospital Universitário João de Barros Barreto. Departamento de Cirurgia. Belém, PA, Brasil.Universidade Federal do Ceará. Centro de Ciências da Saúde. Departamento de Patologia. Fortaleza, CE, Brasil.Universidade Federal de São Paulo. Departamento de Morfologia e Genética. Disciplina de Genética. São Paulo, SP. Brasil.Ministério da Saúde. Fundação Nacional de Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Universidade Federal do Pará. Instituto de Ciências Biológicas. Laboratório de Citogenética Humana. Belém, PA, Brasil.Universidade Federal do Pará. Instituto de Ciências Biológicas. Laboratório de Citogenética Humana. Belém, PA, Brasil.application/pdfengInstituto Oswaldo CruzLow frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleNeoplasias da Próstata / diagnósticoPapillomaviridae / genéticaInfecções por PapillomavirusHiperplasia Prostática / diagnósticoGenitália MasculinaDoenças dos Genitais Masculinosinfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALLow frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil.pdfapplication/pdf440914https://patua.iec.gov.br/bitstreams/cb4c9d56-b952-43a6-9a45-b0866a69e69f/download3e6dd2a9e278e52ae269e4c6b6e8834aMD51TEXTfile_1.pdf.txtfile_1.pdf.txtExtracted texttext/plain15124https://patua.iec.gov.br/bitstreams/5f68e1d9-9ec3-4e00-b9d4-f6fef55a365e/download993e3148820079f8bd0689d9c4272e36MD52Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil.pdf.txtLow frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil.pdf.txtExtracted texttext/plain15193https://patua.iec.gov.br/bitstreams/e5284aa2-f05b-4253-9374-7ca619a32450/downloadfc9a5f6238798334a3b08643cca8bfe7MD57THUMBNAILfile_1.pdf.jpgfile_1.pdf.jpgIM Thumbnailimage/jpeg4832https://patua.iec.gov.br/bitstreams/39a1b218-7602-413c-be06-a93ad22de018/downloaddbeb292bcf1e252f6742bf521a49243bMD53Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil.pdf.jpgLow frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil.pdf.jpgGenerated Thumbnailimage/jpeg5879https://patua.iec.gov.br/bitstreams/bd436698-f96e-40d0-9f77-eb7715338119/downloadd347463b89c5a7827273b4c34a70359bMD58LICENSElicense.txtlicense.txttext/plain; charset=utf-82182https://patua.iec.gov.br/bitstreams/0d86969b-db6c-4935-bc5c-5ed58951224d/download11832eea31b16df8613079d742d61793MD56iec/9342022-10-20 23:08:03.751oai:patua.iec.gov.br:iec/934https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T23:08:03Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)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
dc.title.pt_BR.fl_str_mv Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil
title Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil
spellingShingle Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil
Silvestre, Rodrigo Vellasco Duarte
Neoplasias da Próstata / diagnóstico
Papillomaviridae / genética
Infecções por Papillomavirus
Hiperplasia Prostática / diagnóstico
Genitália Masculina
Doenças dos Genitais Masculinos
title_short Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil
title_full Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil
title_fullStr Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil
title_full_unstemmed Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil
title_sort Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil
author Silvestre, Rodrigo Vellasco Duarte
author_facet Silvestre, Rodrigo Vellasco Duarte
Leal, Mariana Ferreira
Demachki, Samia
Nahum, Márcia Cristina de Souza
Bernardes, Julio Guilherme Balieiro
Rabenhorst, Silvia Helena Barem
Smith, Marília de Arruda Cardoso
Mello, Wyller Alencar de
Guimarães, Adriana Costa
Burbano, Rommel Rodríguez
author_role author
author2 Leal, Mariana Ferreira
Demachki, Samia
Nahum, Márcia Cristina de Souza
Bernardes, Julio Guilherme Balieiro
Rabenhorst, Silvia Helena Barem
Smith, Marília de Arruda Cardoso
Mello, Wyller Alencar de
Guimarães, Adriana Costa
Burbano, Rommel Rodríguez
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silvestre, Rodrigo Vellasco Duarte
Leal, Mariana Ferreira
Demachki, Samia
Nahum, Márcia Cristina de Souza
Bernardes, Julio Guilherme Balieiro
Rabenhorst, Silvia Helena Barem
Smith, Marília de Arruda Cardoso
Mello, Wyller Alencar de
Guimarães, Adriana Costa
Burbano, Rommel Rodríguez
dc.subject.decsPrimary.pt_BR.fl_str_mv Neoplasias da Próstata / diagnóstico
Papillomaviridae / genética
Infecções por Papillomavirus
Hiperplasia Prostática / diagnóstico
Genitália Masculina
Doenças dos Genitais Masculinos
topic Neoplasias da Próstata / diagnóstico
Papillomaviridae / genética
Infecções por Papillomavirus
Hiperplasia Prostática / diagnóstico
Genitália Masculina
Doenças dos Genitais Masculinos
description The presence of human papillomavirus (HPV) was evaluated in 65 samples of prostate tumours and six samples of prostates with benign prostatic hyperplasia from individuals from Northern Brazil. We used a highly sensitive test, the Linear Array HPV Genotyping Test, to detect 37 high and low-risk HPV types. In this study, only 3% of tumour samples showed HPV infection. Our findings support the conclusion that, despite the high incidence of HPV infection in the geographic regions studied, HPV was not associated with a higher risk of prostate cancer. To our knowledge, this is the first study evaluating the frequency of HPV detection in prostatic tissue of individuals from Brazil.
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2016-01-26T11:39:48Z
dc.date.available.fl_str_mv 2016-01-26T11:39:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVESTRE, Rodrigo Vellasco Duarte et al. Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil. Memórias do Instituto Oswaldo Cruz, v. 104, n. 4, p. 665-667, 2009
dc.identifier.uri.fl_str_mv https://patua.iec.gov.br/handle/iec/934
dc.identifier.issn.-.fl_str_mv 0074-0276
identifier_str_mv SILVESTRE, Rodrigo Vellasco Duarte et al. Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil. Memórias do Instituto Oswaldo Cruz, v. 104, n. 4, p. 665-667, 2009
0074-0276
url https://patua.iec.gov.br/handle/iec/934
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz
publisher.none.fl_str_mv Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Digital do Instituto Evandro Chagas (Patuá)
instname:Instituto Evandro Chagas (IEC)
instacron:IEC
instname_str Instituto Evandro Chagas (IEC)
instacron_str IEC
institution IEC
reponame_str Repositório Digital do Instituto Evandro Chagas (Patuá)
collection Repositório Digital do Instituto Evandro Chagas (Patuá)
bitstream.url.fl_str_mv https://patua.iec.gov.br/bitstreams/cb4c9d56-b952-43a6-9a45-b0866a69e69f/download
https://patua.iec.gov.br/bitstreams/5f68e1d9-9ec3-4e00-b9d4-f6fef55a365e/download
https://patua.iec.gov.br/bitstreams/e5284aa2-f05b-4253-9374-7ca619a32450/download
https://patua.iec.gov.br/bitstreams/39a1b218-7602-413c-be06-a93ad22de018/download
https://patua.iec.gov.br/bitstreams/bd436698-f96e-40d0-9f77-eb7715338119/download
https://patua.iec.gov.br/bitstreams/0d86969b-db6c-4935-bc5c-5ed58951224d/download
bitstream.checksum.fl_str_mv 3e6dd2a9e278e52ae269e4c6b6e8834a
993e3148820079f8bd0689d9c4272e36
fc9a5f6238798334a3b08643cca8bfe7
dbeb292bcf1e252f6742bf521a49243b
d347463b89c5a7827273b4c34a70359b
11832eea31b16df8613079d742d61793
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)
repository.mail.fl_str_mv clariceneta@iec.gov.br || Biblioteca@iec.gov.br
_version_ 1809190052040802304