Nosocomial transmission of an avian-like rotavirus strain among children in Belém, Brazil.

• Autor(a) principal: Gusmão, Rosa Helena P
• Data de Publicação: 1994
• Outros Autores: Mascarenhas, Joana D'Arc Pereira, Gabbay, Yvone Benchimol, Linhares, Alexandre da Costa
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
• Texto Completo: https://patua.iec.gov.br/handle/iec/2729
• topic: Diarreia Infantil / complicações; Rotavirus; Infecções por Rotavirus / isolamento & purificação; Infecções por Rotavirus / virologia; Ensaio de Imunoadsorção Enzimática / métodos

An atypical group-A rotavirus strain, with an electrophoretype displaying 5 segments in the first dsRNA size class, was detected among 3 hospitalized children less than 2 years old. Detection occurred initially 24 h after admission in a non-diarrhoeic child hospitalized because of acute respiratory infection. The second detection involved a child who occupied a different room within the same ward and who developed nosocomial diarrhoea 48 h later. A third case, also of hospital-acquired diarrhoea, was recorded in a child who occupied a bed in the same room as the second case and developed gastroenteritis 24 h following the second case's detection. In addition to the unusual, avian-like genomic profile, the strain was classified as serotype 2, based on a human VP7-specific enzyme-linked immunosorbent assay (ELISA). The question of whether these events reflect either a genomic rearrangement of a human rotavirus strain or a possible interspecies transmission will be further investigated through hybridization assays.