Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization
Autor(a) principal: | |
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Data de Publicação: | 1976 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
Texto Completo: | https://patua.iec.gov.br/handle/iec/960 |
Resumo: | Vaccination of two virgin-soil (without historical or serological evidence of past infection) populations of Amazon lndians with RA 27/3 rubella vaccine was followed by rever of > 100 F in 10% of the vacinees and by ephemeral arthralgia in 2 %. These frequencies are not greater than those that have been reported for cosmopolitan populations of comparable ages. There was little or no secondary spread of the virus. Titers of hemagglutination-inhibiting antibody to rubella virus were prevalent in a third population of Amazon lndians, who had naturally acquired immunity and were unexposed to reinfection, and did not decline during a period of four to 12 years after infection. Antibody titers in the two virgin-soil populations immunized with RA 27/3 vaccine declined by twofold between four months and two and one-half years after vaccination but, at the end of that period, were not appreciably lower than antibody titers at four years in the naturally infected population. AlI age groups except chiIdren under one year of age responded to vaccination equally weII. |
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Black, Francis LeeLamm, Steven HEmmons, Jean EPinheiro, Francisco de Paula2016-01-26T11:39:51Z2016-01-26T11:39:51Z1976BLACK, Francis L. et al. Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization. Journal of Infectious Diseases, v. 133, n. 4, p. 393-398, 1976.0022-1899https://patua.iec.gov.br/handle/iec/960Vaccination of two virgin-soil (without historical or serological evidence of past infection) populations of Amazon lndians with RA 27/3 rubella vaccine was followed by rever of > 100 F in 10% of the vacinees and by ephemeral arthralgia in 2 %. These frequencies are not greater than those that have been reported for cosmopolitan populations of comparable ages. There was little or no secondary spread of the virus. Titers of hemagglutination-inhibiting antibody to rubella virus were prevalent in a third population of Amazon lndians, who had naturally acquired immunity and were unexposed to reinfection, and did not decline during a period of four to 12 years after infection. Antibody titers in the two virgin-soil populations immunized with RA 27/3 vaccine declined by twofold between four months and two and one-half years after vaccination but, at the end of that period, were not appreciably lower than antibody titers at four years in the naturally infected population. AlI age groups except chiIdren under one year of age responded to vaccination equally weII.Yale University. School of Medicine. Department of Epidemiology and Public Health. Yale, USA.National Institutes of Health. The National Institute of Child Health and Human Development. Bethesda, Maryland, USA.National Institutes of Health. The National Institute of Child Health and Human Development. Bethesda, Maryland, USA.Ministério da Saúde. Fundação Oswaldo Cruz. Instituto Evandro Chagas. 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dc.title.pt_BR.fl_str_mv |
Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization |
title |
Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization |
spellingShingle |
Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization Black, Francis Lee Vacina contra Rubéola / administração & dosagem Vacina contra Rubéola / efeitos adversos Vacina contra Rubéola / uso terapêutico Vacina contra Rubéola / imunologia Índios Sul-Americanos |
title_short |
Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization |
title_full |
Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization |
title_fullStr |
Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization |
title_full_unstemmed |
Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization |
title_sort |
Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization |
author |
Black, Francis Lee |
author_facet |
Black, Francis Lee Lamm, Steven H Emmons, Jean E Pinheiro, Francisco de Paula |
author_role |
author |
author2 |
Lamm, Steven H Emmons, Jean E Pinheiro, Francisco de Paula |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Black, Francis Lee Lamm, Steven H Emmons, Jean E Pinheiro, Francisco de Paula |
dc.subject.decsPrimary.pt_BR.fl_str_mv |
Vacina contra Rubéola / administração & dosagem Vacina contra Rubéola / efeitos adversos Vacina contra Rubéola / uso terapêutico Vacina contra Rubéola / imunologia Índios Sul-Americanos |
topic |
Vacina contra Rubéola / administração & dosagem Vacina contra Rubéola / efeitos adversos Vacina contra Rubéola / uso terapêutico Vacina contra Rubéola / imunologia Índios Sul-Americanos |
description |
Vaccination of two virgin-soil (without historical or serological evidence of past infection) populations of Amazon lndians with RA 27/3 rubella vaccine was followed by rever of > 100 F in 10% of the vacinees and by ephemeral arthralgia in 2 %. These frequencies are not greater than those that have been reported for cosmopolitan populations of comparable ages. There was little or no secondary spread of the virus. Titers of hemagglutination-inhibiting antibody to rubella virus were prevalent in a third population of Amazon lndians, who had naturally acquired immunity and were unexposed to reinfection, and did not decline during a period of four to 12 years after infection. Antibody titers in the two virgin-soil populations immunized with RA 27/3 vaccine declined by twofold between four months and two and one-half years after vaccination but, at the end of that period, were not appreciably lower than antibody titers at four years in the naturally infected population. AlI age groups except chiIdren under one year of age responded to vaccination equally weII. |
publishDate |
1976 |
dc.date.issued.fl_str_mv |
1976 |
dc.date.accessioned.fl_str_mv |
2016-01-26T11:39:51Z |
dc.date.available.fl_str_mv |
2016-01-26T11:39:51Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BLACK, Francis L. et al. Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization. Journal of Infectious Diseases, v. 133, n. 4, p. 393-398, 1976. |
dc.identifier.uri.fl_str_mv |
https://patua.iec.gov.br/handle/iec/960 |
dc.identifier.issn.-.fl_str_mv |
0022-1899 |
identifier_str_mv |
BLACK, Francis L. et al. Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization. Journal of Infectious Diseases, v. 133, n. 4, p. 393-398, 1976. 0022-1899 |
url |
https://patua.iec.gov.br/handle/iec/960 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Oxford University Press |
publisher.none.fl_str_mv |
Oxford University Press |
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reponame:Repositório Digital do Instituto Evandro Chagas (Patuá) instname:Instituto Evandro Chagas (IEC) instacron:IEC |
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IEC |
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IEC |
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Repositório Digital do Instituto Evandro Chagas (Patuá) |
collection |
Repositório Digital do Instituto Evandro Chagas (Patuá) |
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