Canine antibody response to Lutzomyia longipalpis saliva in endemic area of visceral leishmaniasis

• Autor(a) principal: Batista, Luís Fábio da Silva
• Data de Publicação: 2016
• Outros Autores: Matta, Vânia Lúcia Ribeiro da, Tomokane, Thaise Yumie, Pacheco, Acácio Duarte, Silveira, Fernando Tobias, Rossi, Claudio Nazaretian, Marcondes, Mary, Laurenti, Márcia Dalastra
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
• Texto Completo: https://patua.iec.gov.br/handle/iec/2487
• topic: Leishmania infantum; Leishmaniose Visceral; Saliva; Lutzomyia longipalpis; Doenças do Cão; Imunoglobulina G

Introduction: Canine exposure to Lutzomyia longipalpis bites and the potential of Leishmania infantum transmissibility for the vector were evaluated. Methods: Immunoglobulin G (IgG) anti-Lu longipalpis saliva and -L. infantum, and blood parasite load were determined in dogs from endemic areas of visceral leishmaniasis. Results: Blood parasitism was similar between symptomatic and asymptomatic dogs. IgG anti-L. infantum was higher in symptomatic dogs, but IgG anti-Lu. longipalpis saliva was mostly observed in higher titers in asymptomatic dogs, indicating vector preference for feeding on asymptomatic dogs. Conclusions: Our data suggest a pivotal role of asymptomatic dogs in L. infantum transmission in endemic areas.