Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil.
Autor(a) principal: | |
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Data de Publicação: | 1988 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
Texto Completo: | https://patua.iec.gov.br/handle/iec/2732 |
Resumo: | An outbreak of pharyngoconjunctival fever caused by adenovirus (Ad) occurred in 1976 in Belem (northern Brazil). By restriction endonuclease analysis, it was shown that the type responsible was Ad4a, a variant of Ad4 prototype (Ad4p) and previously described as causative agent of ocular diseases. In an epidemiologic study carried out in Rio de Janeiro and Belem between 1977 and 1986, 148 Ads were isolated from children with respiratory disease. All five Ad4 strains encountered during this study were also Ad4a. This type, circulating in South America, can therefore cause both ocular and respiratory diseases. No Ad4p was isolated during this study. A percent of comigrating restriction fragments of only 50% between Ad4p and Ad4a was calculated from 13 restriction enzyme patterns. The restriction maps of Ad4a for nine endonucleases are presented and compared with those of Ad4p. |
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Gomes, S. AGabbay, Yvone BenchimolNascimento, J. PNiel, C2017-09-12T15:44:08Z2017-09-12T15:44:08Z1988GOMES, S. A. et al. Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil. Journal of Medical Virology, v. 26, n. 4, p. 453-459, Dec. 1988.0146-6615https://patua.iec.gov.br/handle/iec/2732An outbreak of pharyngoconjunctival fever caused by adenovirus (Ad) occurred in 1976 in Belem (northern Brazil). By restriction endonuclease analysis, it was shown that the type responsible was Ad4a, a variant of Ad4 prototype (Ad4p) and previously described as causative agent of ocular diseases. In an epidemiologic study carried out in Rio de Janeiro and Belem between 1977 and 1986, 148 Ads were isolated from children with respiratory disease. All five Ad4 strains encountered during this study were also Ad4a. This type, circulating in South America, can therefore cause both ocular and respiratory diseases. No Ad4p was isolated during this study. A percent of comigrating restriction fragments of only 50% between Ad4p and Ad4a was calculated from 13 restriction enzyme patterns. The restriction maps of Ad4a for nine endonucleases are presented and compared with those of Ad4p.Fundação Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brazil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.Fundação Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brazil.Fundação Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brazil.engWileyGenome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAdenovírus Humanos / isolamento & purificaçãoInfecções por Adenovirus Humanos / isolamento & purificaçãoConjuntiviteMapeamento por RestriçãoInfecções por Adenovirus Humanos / epidemiologiainfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALGenome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil.pdfGenome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil.pdfapplication/pdf924080https://patua.iec.gov.br/bitstreams/7fd7f2f6-6c9b-4a58-95fc-72488d2fcdc3/download4445aa21e7f553fc37fda5b35a143e74MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-871https://patua.iec.gov.br/bitstreams/3b98b999-8334-428e-ae70-ce498bcda68d/download52f1732ea66fbd1123abe39f5373b797MD52TEXTGenome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil.pdf.txtGenome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil.pdf.txtExtracted texttext/plain17642https://patua.iec.gov.br/bitstreams/19328f24-473a-4cad-bfe3-2beb19b9d477/download9ef6cf387b348ee0d18eb5f0df421388MD55THUMBNAILGenome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil.pdf.jpgGenome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil.pdf.jpgGenerated Thumbnailimage/jpeg6000https://patua.iec.gov.br/bitstreams/c7b2f7c0-c0e7-427e-8c28-fea1297330e1/downloada0b6bcbcfd0b4a2c0b60e3fe861f76f5MD56iec/27322022-10-20 22:10:09.815oai:patua.iec.gov.br:iec/2732https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T22:10:09Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)falseVG9kb3Mgb3MgZG9jdW1lbnRvcyBkZXNzYSBjb2xlw6fDo28gc2VndWVtIGEgTGljZW7Dp2EgQ3JlYXRpdmUgY29tbW9ucy4= |
dc.title.pt_BR.fl_str_mv |
Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil. |
title |
Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil. |
spellingShingle |
Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil. Gomes, S. A Adenovírus Humanos / isolamento & purificação Infecções por Adenovirus Humanos / isolamento & purificação Conjuntivite Mapeamento por Restrição Infecções por Adenovirus Humanos / epidemiologia |
title_short |
Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil. |
title_full |
Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil. |
title_fullStr |
Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil. |
title_full_unstemmed |
Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil. |
title_sort |
Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil. |
author |
Gomes, S. A |
author_facet |
Gomes, S. A Gabbay, Yvone Benchimol Nascimento, J. P Niel, C |
author_role |
author |
author2 |
Gabbay, Yvone Benchimol Nascimento, J. P Niel, C |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Gomes, S. A Gabbay, Yvone Benchimol Nascimento, J. P Niel, C |
dc.subject.decsPrimary.pt_BR.fl_str_mv |
Adenovírus Humanos / isolamento & purificação Infecções por Adenovirus Humanos / isolamento & purificação Conjuntivite Mapeamento por Restrição Infecções por Adenovirus Humanos / epidemiologia |
topic |
Adenovírus Humanos / isolamento & purificação Infecções por Adenovirus Humanos / isolamento & purificação Conjuntivite Mapeamento por Restrição Infecções por Adenovirus Humanos / epidemiologia |
description |
An outbreak of pharyngoconjunctival fever caused by adenovirus (Ad) occurred in 1976 in Belem (northern Brazil). By restriction endonuclease analysis, it was shown that the type responsible was Ad4a, a variant of Ad4 prototype (Ad4p) and previously described as causative agent of ocular diseases. In an epidemiologic study carried out in Rio de Janeiro and Belem between 1977 and 1986, 148 Ads were isolated from children with respiratory disease. All five Ad4 strains encountered during this study were also Ad4a. This type, circulating in South America, can therefore cause both ocular and respiratory diseases. No Ad4p was isolated during this study. A percent of comigrating restriction fragments of only 50% between Ad4p and Ad4a was calculated from 13 restriction enzyme patterns. The restriction maps of Ad4a for nine endonucleases are presented and compared with those of Ad4p. |
publishDate |
1988 |
dc.date.issued.fl_str_mv |
1988 |
dc.date.accessioned.fl_str_mv |
2017-09-12T15:44:08Z |
dc.date.available.fl_str_mv |
2017-09-12T15:44:08Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
GOMES, S. A. et al. Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil. Journal of Medical Virology, v. 26, n. 4, p. 453-459, Dec. 1988. |
dc.identifier.uri.fl_str_mv |
https://patua.iec.gov.br/handle/iec/2732 |
dc.identifier.issn.-.fl_str_mv |
0146-6615 |
identifier_str_mv |
GOMES, S. A. et al. Genome analysis of adenovirus 4a, a causative agent of pharyngoconjunctival fever and respiratory diseases in Brazil. Journal of Medical Virology, v. 26, n. 4, p. 453-459, Dec. 1988. 0146-6615 |
url |
https://patua.iec.gov.br/handle/iec/2732 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Wiley |
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Wiley |
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