Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
Texto Completo: | http://patua.iec.gov.br//handle/iec/4306 |
Resumo: | The hepatitis A virus (HAV, Hepatovirus A) in humans has a relevant impact on public health, especially in geographic regions with poor basic sanitation, such as the Brazilian Amazon. Isolates related to hepatoviruses have been described in non human primates, chiropterans, marsupials, rodents, marmots, shrews, and terrestrial hedgehogs. However, the circulation of these viruses in the Amazonian mammal fauna remains unexplored. This study aimed to evaluate the prevalence of antibodies against this hepatovirus in captive and free-living wild mammals belonging to the orders Didelphimorphia, Primates, Carnivora, and Artiodactyla. Serum samples from 71 animals, from three municipalities in the State of Pará (Belém, Santarém, and CapitãoPoço) were tested for total anti-HAV and anti-HAV IgM through enzyme-linked immunosorbent assay (ELISA). Total anti-HAV antibodies were detected in 29.5% (21/71) of non-human primates, 8.4% (6/71) of carnivores, and 5.6% (4/71) of didelphos. All tayassuidos 0% (0/2) were seronegative. Anti-HAV IgM antibodies were not detected in any of the samples tested. The highest total anti-HAV seropositivity in the municipalities studied was in Santarém with 54.24% (12/22), followed by Capitão Poço with 50% (15/30), and then Belém with 21.05% (4/19). Among the seropositive animals, animals kept in exposure cages showed 43.9% (18/41), quarantined animals with 60% (9/15), and free-living animals with 26.6% (4/15). The serological results indicated a profile of previous exposure to hepatovirus among these animals. Therefore, additional studies to characterize HAV-related viruses in captive and free living wild animals need to be conducted to better understand the impact of the circulation of this virus on human and animal health. |
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Bernal, Marcella Katheryne MarquesSouza, Alex Júnior Souza deNunes, Heloisa MarcelianoMalheiros, Andreza PinheiroChagas, André Antônio Corrêa dasAndrade, Sara Letícia dos SantosFigueiredo, Andréa Lima SilvaCecim, Amanda Desirée AssunçãoPereira, Washington Luiz Assunção2021-05-13T13:00:19Z2021-05-13T13:00:19Z2021BERNAL, Marcella Katheryne Marques et al. Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil. Semina: Ciências Agrárias, v. 42, n. 3 Supl. 1, p. 1635-1646, 2021.1679-0359http://patua.iec.gov.br//handle/iec/430610.5433/1679-0359.2021v42n3Supl1p1635The hepatitis A virus (HAV, Hepatovirus A) in humans has a relevant impact on public health, especially in geographic regions with poor basic sanitation, such as the Brazilian Amazon. Isolates related to hepatoviruses have been described in non human primates, chiropterans, marsupials, rodents, marmots, shrews, and terrestrial hedgehogs. However, the circulation of these viruses in the Amazonian mammal fauna remains unexplored. This study aimed to evaluate the prevalence of antibodies against this hepatovirus in captive and free-living wild mammals belonging to the orders Didelphimorphia, Primates, Carnivora, and Artiodactyla. Serum samples from 71 animals, from three municipalities in the State of Pará (Belém, Santarém, and CapitãoPoço) were tested for total anti-HAV and anti-HAV IgM through enzyme-linked immunosorbent assay (ELISA). Total anti-HAV antibodies were detected in 29.5% (21/71) of non-human primates, 8.4% (6/71) of carnivores, and 5.6% (4/71) of didelphos. All tayassuidos 0% (0/2) were seronegative. Anti-HAV IgM antibodies were not detected in any of the samples tested. The highest total anti-HAV seropositivity in the municipalities studied was in Santarém with 54.24% (12/22), followed by Capitão Poço with 50% (15/30), and then Belém with 21.05% (4/19). Among the seropositive animals, animals kept in exposure cages showed 43.9% (18/41), quarantined animals with 60% (9/15), and free-living animals with 26.6% (4/15). The serological results indicated a profile of previous exposure to hepatovirus among these animals. Therefore, additional studies to characterize HAV-related viruses in captive and free living wild animals need to be conducted to better understand the impact of the circulation of this virus on human and animal health.Federal Rural University of the Amazon. Pós-Graduate Program Animal Healt and Production in the Amazon. Belém, PA, Brazil.University Paulista. São Paulo, SP, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Federal Rural University of Amazon. Belém, PA, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Programa de Pós-Graduação em Virologia. Ananindeua, PA, Brasil.Federal Rural University of the Amazon. Departament Animal Pathology. Belém, PA, Brazil.engUniversidade do Estado de LondrinaSerological markers for hepatitis a among captive and free-living wild mammals in the State of Para, BrazilMarcadores sorológicos para hepatite A entre mamíferos silvestres cativos e de vida livre do Estado do Pará, Brasilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHepatite A / patologiaAnticorpos Anti-Hepatite AAnimais Selvagens / anatomia & histologiaHepatovirus / patogenicidadeEnsaio de Imunoadsorção Enzimática / métodosSaneamento BásicoEcossistema AmazônicoBelém (PA)Santarém (PA)Capitão-Poço (PA)info:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECLICENSElicense.txtlicense.txttext/plain; charset=utf-82182https://patua.iec.gov.br/bitstreams/a7dabd5e-463c-418c-b0f0-5534d7d1fc79/download11832eea31b16df8613079d742d61793MD52ORIGINALSerological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil.pdfSerological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil.pdfapplication/pdf189056https://patua.iec.gov.br/bitstreams/bed7309e-0dda-4eb3-bbc4-50c5064eacd7/download009d87270e90e18e139ced76d13d54faMD51TEXTSerological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil.pdf.txtSerological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil.pdf.txtExtracted texttext/plain32562https://patua.iec.gov.br/bitstreams/e2127edf-132c-4a77-a86f-ede9bc4db1f2/download976f8eb54912643c04c0811261b82834MD55THUMBNAILSerological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil.pdf.jpgSerological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil.pdf.jpgGenerated Thumbnailimage/jpeg6492https://patua.iec.gov.br/bitstreams/2672a23a-0d18-413e-8a3b-3c8e75c47ecc/downloade92499f6e36ac2b309e0187926ff1e21MD56iec/43062022-10-20 21:22:01.804oai:patua.iec.gov.br:iec/4306https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T21:22:01Repositório Digital do Instituto Evandro Chagas (Patuá) - 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dc.title.pt_BR.fl_str_mv |
Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil |
dc.title.alternative.pt_BR.fl_str_mv |
Marcadores sorológicos para hepatite A entre mamíferos silvestres cativos e de vida livre do Estado do Pará, Brasil |
title |
Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil |
spellingShingle |
Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil Bernal, Marcella Katheryne Marques Hepatite A / patologia Anticorpos Anti-Hepatite A Animais Selvagens / anatomia & histologia Hepatovirus / patogenicidade Ensaio de Imunoadsorção Enzimática / métodos Saneamento Básico Ecossistema Amazônico Belém (PA) Santarém (PA) Capitão-Poço (PA) |
title_short |
Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil |
title_full |
Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil |
title_fullStr |
Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil |
title_full_unstemmed |
Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil |
title_sort |
Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil |
author |
Bernal, Marcella Katheryne Marques |
author_facet |
Bernal, Marcella Katheryne Marques Souza, Alex Júnior Souza de Nunes, Heloisa Marceliano Malheiros, Andreza Pinheiro Chagas, André Antônio Corrêa das Andrade, Sara Letícia dos Santos Figueiredo, Andréa Lima Silva Cecim, Amanda Desirée Assunção Pereira, Washington Luiz Assunção |
author_role |
author |
author2 |
Souza, Alex Júnior Souza de Nunes, Heloisa Marceliano Malheiros, Andreza Pinheiro Chagas, André Antônio Corrêa das Andrade, Sara Letícia dos Santos Figueiredo, Andréa Lima Silva Cecim, Amanda Desirée Assunção Pereira, Washington Luiz Assunção |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Bernal, Marcella Katheryne Marques Souza, Alex Júnior Souza de Nunes, Heloisa Marceliano Malheiros, Andreza Pinheiro Chagas, André Antônio Corrêa das Andrade, Sara Letícia dos Santos Figueiredo, Andréa Lima Silva Cecim, Amanda Desirée Assunção Pereira, Washington Luiz Assunção |
dc.subject.decsPrimary.pt_BR.fl_str_mv |
Hepatite A / patologia Anticorpos Anti-Hepatite A Animais Selvagens / anatomia & histologia Hepatovirus / patogenicidade Ensaio de Imunoadsorção Enzimática / métodos Saneamento Básico Ecossistema Amazônico Belém (PA) Santarém (PA) Capitão-Poço (PA) |
topic |
Hepatite A / patologia Anticorpos Anti-Hepatite A Animais Selvagens / anatomia & histologia Hepatovirus / patogenicidade Ensaio de Imunoadsorção Enzimática / métodos Saneamento Básico Ecossistema Amazônico Belém (PA) Santarém (PA) Capitão-Poço (PA) |
description |
The hepatitis A virus (HAV, Hepatovirus A) in humans has a relevant impact on public health, especially in geographic regions with poor basic sanitation, such as the Brazilian Amazon. Isolates related to hepatoviruses have been described in non human primates, chiropterans, marsupials, rodents, marmots, shrews, and terrestrial hedgehogs. However, the circulation of these viruses in the Amazonian mammal fauna remains unexplored. This study aimed to evaluate the prevalence of antibodies against this hepatovirus in captive and free-living wild mammals belonging to the orders Didelphimorphia, Primates, Carnivora, and Artiodactyla. Serum samples from 71 animals, from three municipalities in the State of Pará (Belém, Santarém, and CapitãoPoço) were tested for total anti-HAV and anti-HAV IgM through enzyme-linked immunosorbent assay (ELISA). Total anti-HAV antibodies were detected in 29.5% (21/71) of non-human primates, 8.4% (6/71) of carnivores, and 5.6% (4/71) of didelphos. All tayassuidos 0% (0/2) were seronegative. Anti-HAV IgM antibodies were not detected in any of the samples tested. The highest total anti-HAV seropositivity in the municipalities studied was in Santarém with 54.24% (12/22), followed by Capitão Poço with 50% (15/30), and then Belém with 21.05% (4/19). Among the seropositive animals, animals kept in exposure cages showed 43.9% (18/41), quarantined animals with 60% (9/15), and free-living animals with 26.6% (4/15). The serological results indicated a profile of previous exposure to hepatovirus among these animals. Therefore, additional studies to characterize HAV-related viruses in captive and free living wild animals need to be conducted to better understand the impact of the circulation of this virus on human and animal health. |
publishDate |
2021 |
dc.date.accessioned.fl_str_mv |
2021-05-13T13:00:19Z |
dc.date.available.fl_str_mv |
2021-05-13T13:00:19Z |
dc.date.issued.fl_str_mv |
2021 |
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dc.identifier.citation.fl_str_mv |
BERNAL, Marcella Katheryne Marques et al. Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil. Semina: Ciências Agrárias, v. 42, n. 3 Supl. 1, p. 1635-1646, 2021. |
dc.identifier.uri.fl_str_mv |
http://patua.iec.gov.br//handle/iec/4306 |
dc.identifier.issn.-.fl_str_mv |
1679-0359 |
dc.identifier.doi.-.fl_str_mv |
10.5433/1679-0359.2021v42n3Supl1p1635 |
identifier_str_mv |
BERNAL, Marcella Katheryne Marques et al. Serological markers for hepatitis a among captive and free-living wild mammals in the State of Para, Brazil. Semina: Ciências Agrárias, v. 42, n. 3 Supl. 1, p. 1635-1646, 2021. 1679-0359 10.5433/1679-0359.2021v42n3Supl1p1635 |
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http://patua.iec.gov.br//handle/iec/4306 |
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eng |
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eng |
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Universidade do Estado de Londrina |
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Universidade do Estado de Londrina |
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