Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector
Autor(a) principal: | |
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Data de Publicação: | 1985 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
Texto Completo: | https://patua.iec.gov.br/handle/iec/2775 |
Resumo: | Further evidence is presented incriminating the sandfly Lutzomyia longipalpis as the vector of Leishmania chagasi, the causative agent of American visceral leishmaniasis, in the Amazon Region of Brazil. During an outbreak of the disease in Santarém, Pará State, this insect was shown to be the only species of sandfly consistently present in and around the patient's homes, where it often occurred in very large numbers. Of 491 specimens dissected, 35 (7.14%) proved to be infected, and isolates of L. chagasi were made from 16 of 27 of these sandflies following the inoculation of the promastigotes into hamsters. Finally, the parasite was transmitted to four other hamsters which had been subjected to the bites of large numbers of wild-caught Lu. longipalpis. Isolates of Leishmania from Lu. longipalpis captures in Santarém, and in another focus of visceral leishmaniasis on the Island of Marajó, Pará, have been shown to be biologically and biochemically indistinguishable from the parasite infecting man, dogs and foxes in Pará, and from stocks obtained from man elsewhere in Brazil (Bahia and Ceará States). |
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Lainson, RalphShaw, Jeffrey JonRyan, LRibeiro, R. S. MSilveira, Fernando Tobias2017-09-28T14:47:28Z2017-09-28T14:47:28Z1985LAINSON, Ralph et al. Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector. Transactions of The Royal Society of Tropical Medicine and Hygiene, v. 79, n. 2, p. 223-226, 1985.0035-9203https://patua.iec.gov.br/handle/iec/277510.1016/0035-9203(85)90340-2Further evidence is presented incriminating the sandfly Lutzomyia longipalpis as the vector of Leishmania chagasi, the causative agent of American visceral leishmaniasis, in the Amazon Region of Brazil. During an outbreak of the disease in Santarém, Pará State, this insect was shown to be the only species of sandfly consistently present in and around the patient's homes, where it often occurred in very large numbers. Of 491 specimens dissected, 35 (7.14%) proved to be infected, and isolates of L. chagasi were made from 16 of 27 of these sandflies following the inoculation of the promastigotes into hamsters. Finally, the parasite was transmitted to four other hamsters which had been subjected to the bites of large numbers of wild-caught Lu. longipalpis. Isolates of Leishmania from Lu. longipalpis captures in Santarém, and in another focus of visceral leishmaniasis on the Island of Marajó, Pará, have been shown to be biologically and biochemically indistinguishable from the parasite infecting man, dogs and foxes in Pará, and from stocks obtained from man elsewhere in Brazil (Bahia and Ceará States).São apresentadas novas evidências, incriminando o flebotomíneo Lutzomyia longipalpis como vetor de leishmaniose visceral na Região Amazônica do Brasil. Durante um surto da doença ocorrido recentemente em Santarém, Estado do Pará, verificou-se ser essa a única espécie de flebotomíneo constantemente presente dentro e nos arredores das casas dos pacientes, usualmente em grande número. Protnastigotos foram encontrados em 3S (7, 14%) de 491 fêmeas de Lu. longipalpis dissecadas, tendo o parasita sido isolado de 16 desses insetos, através da inoculação dos flagelados em hamsters, e transmitido a quatro outros hamsters pela picada de espécimens infectados em natureza. O estudo em Santarém, e de outro foco de leishmaniose visceral registrado na Ilha do Marajó, Pará, mostrou que os isolamentos de Leishmania obtidos de Lu. longipalpis, do homen, de raposas, e de cães, são biologicamente e bioquimicamente indistinguíveis.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Unidade de Estudos Especiais. Belém, PA, Brasil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Unidade de Estudos Especiais. Belém, PA, Brasil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Unidade de Estudos Especiais. Belém, PA, Brasil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Unidade de Estudos Especiais. Belém, PA, Brasil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Unidade de Estudos Especiais. Belém, PA, Brasil.engOxford University PressLeishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vectorinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleLeishmania infantumLeishmaniose VisceralInsetos Vetores / parasitologiaPsychodidae / parasitologiaRegião Norte (BR)Região Amazônica (BR)Santarém (PA)info:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALLeishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector.pdfLeishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector.pdfapplication/pdf885726https://patua.iec.gov.br/bitstreams/3a78896e-a5dc-46db-89ff-b908e7570aa3/downloadf4e87a540d818a381b2054cb16f54004MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-871https://patua.iec.gov.br/bitstreams/b84a0bfd-bb94-43da-850a-2421f8c86b80/download52f1732ea66fbd1123abe39f5373b797MD53TEXTLeishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector.pdf.txtLeishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector.pdf.txtExtracted texttext/plain22966https://patua.iec.gov.br/bitstreams/6dfa7e74-c517-4ed1-860c-4fe1195f8dda/downloadbe6b7df8fa93e2216b240bd29e912999MD56THUMBNAILLeishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector.pdf.jpgLeishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector.pdf.jpgGenerated Thumbnailimage/jpeg7114https://patua.iec.gov.br/bitstreams/84bfda73-746d-40c2-9df1-84dbf72f9f79/download6367f8adebcec58842224c0e7573b9deMD57iec/27752022-10-20 22:04:07.879oai:patua.iec.gov.br:iec/2775https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T22:04:07Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)falseVG9kb3Mgb3MgZG9jdW1lbnRvcyBkZXNzYSBjb2xlw6fDo28gc2VndWVtIGEgTGljZW7Dp2EgQ3JlYXRpdmUgY29tbW9ucy4= |
dc.title.pt_BR.fl_str_mv |
Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector |
title |
Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector |
spellingShingle |
Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector Lainson, Ralph Leishmania infantum Leishmaniose Visceral Insetos Vetores / parasitologia Psychodidae / parasitologia Região Norte (BR) Região Amazônica (BR) Santarém (PA) |
title_short |
Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector |
title_full |
Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector |
title_fullStr |
Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector |
title_full_unstemmed |
Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector |
title_sort |
Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector |
author |
Lainson, Ralph |
author_facet |
Lainson, Ralph Shaw, Jeffrey Jon Ryan, L Ribeiro, R. S. M Silveira, Fernando Tobias |
author_role |
author |
author2 |
Shaw, Jeffrey Jon Ryan, L Ribeiro, R. S. M Silveira, Fernando Tobias |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Lainson, Ralph Shaw, Jeffrey Jon Ryan, L Ribeiro, R. S. M Silveira, Fernando Tobias |
dc.subject.decsPrimary.pt_BR.fl_str_mv |
Leishmania infantum Leishmaniose Visceral Insetos Vetores / parasitologia Psychodidae / parasitologia Região Norte (BR) Região Amazônica (BR) Santarém (PA) |
topic |
Leishmania infantum Leishmaniose Visceral Insetos Vetores / parasitologia Psychodidae / parasitologia Região Norte (BR) Região Amazônica (BR) Santarém (PA) |
description |
Further evidence is presented incriminating the sandfly Lutzomyia longipalpis as the vector of Leishmania chagasi, the causative agent of American visceral leishmaniasis, in the Amazon Region of Brazil. During an outbreak of the disease in Santarém, Pará State, this insect was shown to be the only species of sandfly consistently present in and around the patient's homes, where it often occurred in very large numbers. Of 491 specimens dissected, 35 (7.14%) proved to be infected, and isolates of L. chagasi were made from 16 of 27 of these sandflies following the inoculation of the promastigotes into hamsters. Finally, the parasite was transmitted to four other hamsters which had been subjected to the bites of large numbers of wild-caught Lu. longipalpis. Isolates of Leishmania from Lu. longipalpis captures in Santarém, and in another focus of visceral leishmaniasis on the Island of Marajó, Pará, have been shown to be biologically and biochemically indistinguishable from the parasite infecting man, dogs and foxes in Pará, and from stocks obtained from man elsewhere in Brazil (Bahia and Ceará States). |
publishDate |
1985 |
dc.date.issued.fl_str_mv |
1985 |
dc.date.accessioned.fl_str_mv |
2017-09-28T14:47:28Z |
dc.date.available.fl_str_mv |
2017-09-28T14:47:28Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
LAINSON, Ralph et al. Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector. Transactions of The Royal Society of Tropical Medicine and Hygiene, v. 79, n. 2, p. 223-226, 1985. |
dc.identifier.uri.fl_str_mv |
https://patua.iec.gov.br/handle/iec/2775 |
dc.identifier.issn.-.fl_str_mv |
0035-9203 |
dc.identifier.doi.-.fl_str_mv |
10.1016/0035-9203(85)90340-2 |
identifier_str_mv |
LAINSON, Ralph et al. Leishmaniasis in Brazil XXI: visceral leishmaniasis in the Amazon Region and further observations on the role of Lutzomyia longipalpis (Lutz & Neiva, 1912) as the vector. Transactions of The Royal Society of Tropical Medicine and Hygiene, v. 79, n. 2, p. 223-226, 1985. 0035-9203 10.1016/0035-9203(85)90340-2 |
url |
https://patua.iec.gov.br/handle/iec/2775 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Oxford University Press |
publisher.none.fl_str_mv |
Oxford University Press |
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IEC |
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IEC |
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collection |
Repositório Digital do Instituto Evandro Chagas (Patuá) |
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