Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region

Detalhes bibliográficos
Autor(a) principal: Garcez, Juliana Conceição Dias
Data de Publicação: 2022
Outros Autores: sardinha, Daniele Melo, Conceição, Emilyn Costa, Costa, Gabriel Fazzi, Sousa, Ianny Ferreira Raiol, Mesquita, Cristal Ribeiro, Carmo, Wellington Caldas do, Rodrigues, Yan Corrêa, Lima, Luana Nepomuceno Gondim Costa, Lima, Karla Valéria Batista
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: https://patua.iec.gov.br/handle/iec/4661
Resumo: The city of Ananindeua, State of Pará, Brazil, is a hyperendemic area for tuberculosis (TB). The present study describes the population characteristics and epidemiological indicators of TB cases from Ananindeua, from 2018 to 2020. The TB cases were screened from the Municipal Health Department of Ananindeua database, and the secondary data were obtained from the Brazilian Notifiable Diseases Information System (SINAN). A high percentage of cases did not undergo a rapid molecular test (74.9%) or culture (84.8%) for diagnosis of TB; a chest X-ray examination for diagnosis of TB was performed in 74.47% of new cases. The SINAN form data was incomplete on susceptibility test results (<0.01–92.7). Sputum smear microscopy for monitoring treatment was recorded in the follow-up form in 34.3% and after the 6th month in 61.1% of cases. The cure rate (60.31%) was below the recommendation by the Brazilian Ministry of Health. The quality indicators showed many weaknesses: (I) lack of availability of smear microscopy as a diagnostic test in a hyper-endemic area; (II) low availability of specific exams such as culture and rapid molecular test (RMT); (III) low adherence to smear microscopy to monitor the evolution of cases during treatment; (IV) absence of drug susceptibility test data; (V) failure to fill in essential variables for TB surveillance.
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spelling Garcez, Juliana Conceição Diassardinha, Daniele MeloConceição, Emilyn CostaCosta, Gabriel FazziSousa, Ianny Ferreira RaiolMesquita, Cristal RibeiroCarmo, Wellington Caldas doRodrigues, Yan CorrêaLima, Luana Nepomuceno Gondim CostaLima, Karla Valéria Batista2022-09-12T18:04:39Z2022-09-12T18:04:39Z2022GARCEZ, Juliana Conceição Dias et al. Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region. Tropical Medicine and Infectious Disease, v. 7, n. 8, p. 1-12, Aug. 2022. DOI: https://doi.org/10.3390/tropicalmed7080165; Disponível em: http://patua.iec.gov.br/handle/iec/46612414-6366https://patua.iec.gov.br/handle/iec/466110.3390/tropicalmed7080165The city of Ananindeua, State of Pará, Brazil, is a hyperendemic area for tuberculosis (TB). The present study describes the population characteristics and epidemiological indicators of TB cases from Ananindeua, from 2018 to 2020. The TB cases were screened from the Municipal Health Department of Ananindeua database, and the secondary data were obtained from the Brazilian Notifiable Diseases Information System (SINAN). A high percentage of cases did not undergo a rapid molecular test (74.9%) or culture (84.8%) for diagnosis of TB; a chest X-ray examination for diagnosis of TB was performed in 74.47% of new cases. The SINAN form data was incomplete on susceptibility test results (<0.01–92.7). Sputum smear microscopy for monitoring treatment was recorded in the follow-up form in 34.3% and after the 6th month in 61.1% of cases. The cure rate (60.31%) was below the recommendation by the Brazilian Ministry of Health. The quality indicators showed many weaknesses: (I) lack of availability of smear microscopy as a diagnostic test in a hyper-endemic area; (II) low availability of specific exams such as culture and rapid molecular test (RMT); (III) low adherence to smear microscopy to monitor the evolution of cases during treatment; (IV) absence of drug susceptibility test data; (V) failure to fill in essential variables for TB surveillance.Instituto Evandro Chagas/Ministério da Saúde/Secretaria de Vigilância em Saúde (IEC/MS/SVS). Fundação para o Desenvolvimento Científico e Tecnológico em Saúde (FIOTEC).State University of Pará. Program in Parasitic Biology in the Amazon Region. Belém, PA, Brazil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.State University of Pará. Program in Parasitic Biology in the Amazon Region. Belém, PA, Brazil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Stellenbosch University. Faculty of Medicine and Health Sciences. Division of Molecular Biology and Human Genetics. South African Medical Research Council Centre for Tuberculosis Research. National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research. Department of Science and Innovation. South Africa.State University of Pará. Program in Parasitic Biology in the Amazon Region. Belém, PA, Brazil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.State University of Pará. Program in Parasitic Biology in the Amazon Region. Belém, PA, Brazil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.State University of Pará. Program in Parasitic Biology in the Amazon Region. Belém, PA, Brazil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Secretaria Municipal de Saúde de Ananindeua. Ananindeua, PA, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.State University of Pará. Program in Parasitic Biology in the Amazon Region. Belém, PA, Brazil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.State University of Pará. Program in Parasitic Biology in the Amazon Region. Belém, PA, Brazil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. 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dc.title.pt_BR.fl_str_mv Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region
title Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region
spellingShingle Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region
Garcez, Juliana Conceição Dias
Tuberculose / diagnóstico
Inquéritos Epidemiológicos
Indicadores Demográficos
Estudos Retrospectivos
Ananindeua (PA)
title_short Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region
title_full Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region
title_fullStr Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region
title_full_unstemmed Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region
title_sort Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region
author Garcez, Juliana Conceição Dias
author_facet Garcez, Juliana Conceição Dias
sardinha, Daniele Melo
Conceição, Emilyn Costa
Costa, Gabriel Fazzi
Sousa, Ianny Ferreira Raiol
Mesquita, Cristal Ribeiro
Carmo, Wellington Caldas do
Rodrigues, Yan Corrêa
Lima, Luana Nepomuceno Gondim Costa
Lima, Karla Valéria Batista
author_role author
author2 sardinha, Daniele Melo
Conceição, Emilyn Costa
Costa, Gabriel Fazzi
Sousa, Ianny Ferreira Raiol
Mesquita, Cristal Ribeiro
Carmo, Wellington Caldas do
Rodrigues, Yan Corrêa
Lima, Luana Nepomuceno Gondim Costa
Lima, Karla Valéria Batista
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Garcez, Juliana Conceição Dias
sardinha, Daniele Melo
Conceição, Emilyn Costa
Costa, Gabriel Fazzi
Sousa, Ianny Ferreira Raiol
Mesquita, Cristal Ribeiro
Carmo, Wellington Caldas do
Rodrigues, Yan Corrêa
Lima, Luana Nepomuceno Gondim Costa
Lima, Karla Valéria Batista
dc.subject.decsPrimary.pt_BR.fl_str_mv Tuberculose / diagnóstico
Inquéritos Epidemiológicos
Indicadores Demográficos
Estudos Retrospectivos
Ananindeua (PA)
topic Tuberculose / diagnóstico
Inquéritos Epidemiológicos
Indicadores Demográficos
Estudos Retrospectivos
Ananindeua (PA)
description The city of Ananindeua, State of Pará, Brazil, is a hyperendemic area for tuberculosis (TB). The present study describes the population characteristics and epidemiological indicators of TB cases from Ananindeua, from 2018 to 2020. The TB cases were screened from the Municipal Health Department of Ananindeua database, and the secondary data were obtained from the Brazilian Notifiable Diseases Information System (SINAN). A high percentage of cases did not undergo a rapid molecular test (74.9%) or culture (84.8%) for diagnosis of TB; a chest X-ray examination for diagnosis of TB was performed in 74.47% of new cases. The SINAN form data was incomplete on susceptibility test results (<0.01–92.7). Sputum smear microscopy for monitoring treatment was recorded in the follow-up form in 34.3% and after the 6th month in 61.1% of cases. The cure rate (60.31%) was below the recommendation by the Brazilian Ministry of Health. The quality indicators showed many weaknesses: (I) lack of availability of smear microscopy as a diagnostic test in a hyper-endemic area; (II) low availability of specific exams such as culture and rapid molecular test (RMT); (III) low adherence to smear microscopy to monitor the evolution of cases during treatment; (IV) absence of drug susceptibility test data; (V) failure to fill in essential variables for TB surveillance.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-09-12T18:04:39Z
dc.date.available.fl_str_mv 2022-09-12T18:04:39Z
dc.date.issued.fl_str_mv 2022
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dc.identifier.citation.fl_str_mv GARCEZ, Juliana Conceição Dias et al. Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region. Tropical Medicine and Infectious Disease, v. 7, n. 8, p. 1-12, Aug. 2022. DOI: https://doi.org/10.3390/tropicalmed7080165; Disponível em: http://patua.iec.gov.br/handle/iec/4661
dc.identifier.uri.fl_str_mv https://patua.iec.gov.br/handle/iec/4661
dc.identifier.issn.-.fl_str_mv 2414-6366
dc.identifier.doi.pt_BR.fl_str_mv 10.3390/tropicalmed7080165
identifier_str_mv GARCEZ, Juliana Conceição Dias et al. Surveillance quality indicators highlight the need for improving Tuberculosis diagnostics and monitoring in a hyperendemic area of the Brazilian Amazon Region. Tropical Medicine and Infectious Disease, v. 7, n. 8, p. 1-12, Aug. 2022. DOI: https://doi.org/10.3390/tropicalmed7080165; Disponível em: http://patua.iec.gov.br/handle/iec/4661
2414-6366
10.3390/tropicalmed7080165
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