Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon

Detalhes bibliográficos
Autor(a) principal: Morais, Lena Líllian Canto de Sá
Data de Publicação: 2010
Outros Autores: Fonseca, Érica Lourenço da, Pellegrini, Maíra, Freitas, Fernanda, Loureiro, Edvaldo Carlos Brito, Vicente, Ana Carolina Paulo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: https://patua.iec.gov.br/handle/iec/476
Resumo: This study identified and characterised class 1 and 2 integrons in clinical and environmental Vibrio cholerae O1 and non-O1/non-O139 strains isolated from the Brazilian Amazon. The aadA2 and aadA7 gene cassettes were found in class 1 integrons in two genotypes of environmental V. cholerae non-O1/non-O139. Empty integrons were found in strains from the Brazilian cholera epidemic. A class 2 integron was detected in one strain from the V. cholerae Amazonia lineage harbouring sat1 and aadA1 genes. All isolates were resistant to aminoglycosides, indicating aadA functionality. These findings suggest that environmental bacteria act as cassette reservoirs that favour the emergence of resistant pathogens.
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spelling Morais, Lena Líllian Canto de SáFonseca, Érica Lourenço daPellegrini, MaíraFreitas, FernandaLoureiro, Edvaldo Carlos BritoVicente, Ana Carolina Paulo2016-01-26T11:32:32Z2016-01-26T11:32:32Z2010MORAIS, Lena Líllian Canto de Sá. Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon. Memórias do Instituto Oswaldo Cruz, v. 105, n. 2, p. 229-232, Mar. 20100074-0276https://patua.iec.gov.br/handle/iec/476This study identified and characterised class 1 and 2 integrons in clinical and environmental Vibrio cholerae O1 and non-O1/non-O139 strains isolated from the Brazilian Amazon. The aadA2 and aadA7 gene cassettes were found in class 1 integrons in two genotypes of environmental V. cholerae non-O1/non-O139. Empty integrons were found in strains from the Brazilian cholera epidemic. A class 2 integron was detected in one strain from the V. cholerae Amazonia lineage harbouring sat1 and aadA1 genes. All isolates were resistant to aminoglycosides, indicating aadA functionality. These findings suggest that environmental bacteria act as cassette reservoirs that favour the emergence of resistant pathogens.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. Rio de Janeiro, RJ, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microrganismos. 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dc.title.pt_BR.fl_str_mv Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon
title Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon
spellingShingle Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon
Morais, Lena Líllian Canto de Sá
Vibrio cholerae / isolamento & purificação
Vibrio cholerae / classificação
Reação em Cadeia da Polimerase
Ecossistema Amazônico
Região Amazônica (BR)
title_short Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon
title_full Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon
title_fullStr Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon
title_full_unstemmed Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon
title_sort Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon
author Morais, Lena Líllian Canto de Sá
author_facet Morais, Lena Líllian Canto de Sá
Fonseca, Érica Lourenço da
Pellegrini, Maíra
Freitas, Fernanda
Loureiro, Edvaldo Carlos Brito
Vicente, Ana Carolina Paulo
author_role author
author2 Fonseca, Érica Lourenço da
Pellegrini, Maíra
Freitas, Fernanda
Loureiro, Edvaldo Carlos Brito
Vicente, Ana Carolina Paulo
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Morais, Lena Líllian Canto de Sá
Fonseca, Érica Lourenço da
Pellegrini, Maíra
Freitas, Fernanda
Loureiro, Edvaldo Carlos Brito
Vicente, Ana Carolina Paulo
dc.subject.decsPrimary.pt_BR.fl_str_mv Vibrio cholerae / isolamento & purificação
Vibrio cholerae / classificação
Reação em Cadeia da Polimerase
Ecossistema Amazônico
Região Amazônica (BR)
topic Vibrio cholerae / isolamento & purificação
Vibrio cholerae / classificação
Reação em Cadeia da Polimerase
Ecossistema Amazônico
Região Amazônica (BR)
description This study identified and characterised class 1 and 2 integrons in clinical and environmental Vibrio cholerae O1 and non-O1/non-O139 strains isolated from the Brazilian Amazon. The aadA2 and aadA7 gene cassettes were found in class 1 integrons in two genotypes of environmental V. cholerae non-O1/non-O139. Empty integrons were found in strains from the Brazilian cholera epidemic. A class 2 integron was detected in one strain from the V. cholerae Amazonia lineage harbouring sat1 and aadA1 genes. All isolates were resistant to aminoglycosides, indicating aadA functionality. These findings suggest that environmental bacteria act as cassette reservoirs that favour the emergence of resistant pathogens.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2016-01-26T11:32:32Z
dc.date.available.fl_str_mv 2016-01-26T11:32:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv MORAIS, Lena Líllian Canto de Sá. Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon. Memórias do Instituto Oswaldo Cruz, v. 105, n. 2, p. 229-232, Mar. 2010
dc.identifier.uri.fl_str_mv https://patua.iec.gov.br/handle/iec/476
dc.identifier.issn.-.fl_str_mv 0074-0276
identifier_str_mv MORAIS, Lena Líllian Canto de Sá. Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon. Memórias do Instituto Oswaldo Cruz, v. 105, n. 2, p. 229-232, Mar. 2010
0074-0276
url https://patua.iec.gov.br/handle/iec/476
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