Discovery of novel anelloviruses in small mammals expands the host range and diversity of the Anelloviridae

• Autor(a) principal: Souza, William Marciel de
• Data de Publicação: 2018
• Outros Autores: Fumagalli, Marcílio Jorge, Araujo, Jansen de, Santos Jr, Gilberto Sabino, Maia, Felipe Gonçalves Motta, Romeiro, Marilia Farignoli, Modha, Sejal, Nardi, Marcello Schiavo, Queiroz, Luzia Helena, Durigon, Edison Luiz, Nunes, Márcio Roberto Teixeira, Murcia, Pablo Ramiro, Figueiredo, Luiz Tadeu Moraes
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
• Texto Completo: https://patua.iec.gov.br/handle/iec/3857
• topic: Anelloviridae / genética; Vírus de DNA / genética; Doenças dos Roedores; Roedores / virologia; Anelloviridae / isolamento & purificação; Anelloviridae / genética; Genoma Viral / genética; Sequenciamento de Nucleotídeos em Larga Escala; Variação Genética; Arvicolinae / virologia; Quirópteros / virologia; Especificidade de Hospedeiro / genética; Interações Hospedeiro-Patógeno

The Anelloviridae comprises single-stranded DNA viruses currently grouped in sixty-eight species classified in twelve genera. They have been found in many vertebrate hosts including primates. In this study, we describe the application of the high-throughput sequencing to examine the frequency and diversity of anelloviruses in rodents, bats and opossums captured in São Paulo State, Brazil. We report a total of twenty-six anelloviruses with sixteen nearly complete genomes and ten partial genomes, which include eleven potential novel species identified in rodents (Cricetidae), bats (Molossidae and Phyllostomidae), and opossums (Didelphidae). We also propose the inclusion of two potential new genera within the Anelloviridae family, provisionally named Omegatorquevirus and Sigmatorquevirus, including six and three novel species of anelloviruses, respectively. In summary, this study expands the diversity and the host range of the known anelloviruses.