Lysosomes, Lysosomal Storage Diseases, and Inflammation

Detalhes bibliográficos
Autor(a) principal: Simonaro,Calogera M.
Data de Publicação: 2016
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of Inborn Errors of Metabolism and Screening
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2326-45942016000100317
Resumo: Abstract Lysosomes were originally described in the early 1950s by de Duve who was also the first to recognize the importance of these organelles in human disease. We know now that lysosomes are involved in numerous biological processes, and abnormalities in lysosomal function may result in a broad range of diseases. This review will briefly discuss the role of lysosomes in inflammation and how disruption of normal lysosomal function in the lysosomal storage diseases (LSDs) leads to abnormalities in inflammation and immunity.
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spelling Lysosomes, Lysosomal Storage Diseases, and Inflammationlysosomal storage disordersinflammationAbstract Lysosomes were originally described in the early 1950s by de Duve who was also the first to recognize the importance of these organelles in human disease. We know now that lysosomes are involved in numerous biological processes, and abnormalities in lysosomal function may result in a broad range of diseases. This review will briefly discuss the role of lysosomes in inflammation and how disruption of normal lysosomal function in the lysosomal storage diseases (LSDs) leads to abnormalities in inflammation and immunity.Latin American Society Inborn Errors and Neonatal Screening (SLEIMPN); Instituto Genética para Todos (IGPT)2016-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2326-45942016000100317Journal of Inborn Errors of Metabolism and Screening v.4 2016reponame:Journal of Inborn Errors of Metabolism and Screeninginstname:Instituto Genética para Todos (IGPT)instacron:IGPT10.1177/2326409816650465info:eu-repo/semantics/openAccessSimonaro,Calogera M.eng2019-05-28T00:00:00Zoai:scielo:S2326-45942016000100317Revistahttp://jiems-journal.org/ONGhttps://old.scielo.br/oai/scielo-oai.phpjiems@jiems-journal.org||rgiugliani@hcpa.edu.br2326-45942326-4594opendoar:2019-05-28T00:00Journal of Inborn Errors of Metabolism and Screening - Instituto Genética para Todos (IGPT)false
dc.title.none.fl_str_mv Lysosomes, Lysosomal Storage Diseases, and Inflammation
title Lysosomes, Lysosomal Storage Diseases, and Inflammation
spellingShingle Lysosomes, Lysosomal Storage Diseases, and Inflammation
Simonaro,Calogera M.
lysosomal storage disorders
inflammation
title_short Lysosomes, Lysosomal Storage Diseases, and Inflammation
title_full Lysosomes, Lysosomal Storage Diseases, and Inflammation
title_fullStr Lysosomes, Lysosomal Storage Diseases, and Inflammation
title_full_unstemmed Lysosomes, Lysosomal Storage Diseases, and Inflammation
title_sort Lysosomes, Lysosomal Storage Diseases, and Inflammation
author Simonaro,Calogera M.
author_facet Simonaro,Calogera M.
author_role author
dc.contributor.author.fl_str_mv Simonaro,Calogera M.
dc.subject.por.fl_str_mv lysosomal storage disorders
inflammation
topic lysosomal storage disorders
inflammation
description Abstract Lysosomes were originally described in the early 1950s by de Duve who was also the first to recognize the importance of these organelles in human disease. We know now that lysosomes are involved in numerous biological processes, and abnormalities in lysosomal function may result in a broad range of diseases. This review will briefly discuss the role of lysosomes in inflammation and how disruption of normal lysosomal function in the lysosomal storage diseases (LSDs) leads to abnormalities in inflammation and immunity.
publishDate 2016
dc.date.none.fl_str_mv 2016-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2326-45942016000100317
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2326-45942016000100317
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1177/2326409816650465
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Latin American Society Inborn Errors and Neonatal Screening (SLEIMPN); Instituto Genética para Todos (IGPT)
publisher.none.fl_str_mv Latin American Society Inborn Errors and Neonatal Screening (SLEIMPN); Instituto Genética para Todos (IGPT)
dc.source.none.fl_str_mv Journal of Inborn Errors of Metabolism and Screening v.4 2016
reponame:Journal of Inborn Errors of Metabolism and Screening
instname:Instituto Genética para Todos (IGPT)
instacron:IGPT
instname_str Instituto Genética para Todos (IGPT)
instacron_str IGPT
institution IGPT
reponame_str Journal of Inborn Errors of Metabolism and Screening
collection Journal of Inborn Errors of Metabolism and Screening
repository.name.fl_str_mv Journal of Inborn Errors of Metabolism and Screening - Instituto Genética para Todos (IGPT)
repository.mail.fl_str_mv jiems@jiems-journal.org||rgiugliani@hcpa.edu.br
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