Electrical stimulation attenuates morphological alterations and prevents atrophy of the denervated cranial tibial muscle
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Einstein (São Paulo) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000100071 |
Resumo: | ABSTRACT Objective To investigate if electrical stimulation through Russian current is able to maintain morphology of the cranial tibial muscle of experimentally denervated rats. Methods Thirty-six Wistar rats were divided into four groups: the Initial Control Group, Final Control Group, Experimental Denervated and Treated Group, Experimental Denervated Group. The electrostimulation was performed with a protocol of Russian current applied three times per week, for 45 days. At the end, the animals were euthanized and histological and morphometric analyses were performed. Data were submitted to statistical analysis with a significance level of p<0.05. Results The Experimental Denervated Group and the Experimental Denervated and Treated Group had cross-sectional area of smaller fiber compared to the Final Control Group. However, there was significant difference between the Experimental Denervated Group and Experimental Denervated and Treated Group, showing that electrical stimulation minimized muscle atrophy. The Experimental Denervated and Treated Group and Initial Control Group showed similar results. Conclusion Electrical stimulation through Russian current acted favorably in maintaining morphology of the cranial tibial muscle that was experimentally denervated, minimizing muscle atrophy. |
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Electrical stimulation attenuates morphological alterations and prevents atrophy of the denervated cranial tibial muscleElectric stimulation/methodsMuscle, skeletalMuscular atrophyMuscle denervationRatsABSTRACT Objective To investigate if electrical stimulation through Russian current is able to maintain morphology of the cranial tibial muscle of experimentally denervated rats. Methods Thirty-six Wistar rats were divided into four groups: the Initial Control Group, Final Control Group, Experimental Denervated and Treated Group, Experimental Denervated Group. The electrostimulation was performed with a protocol of Russian current applied three times per week, for 45 days. At the end, the animals were euthanized and histological and morphometric analyses were performed. Data were submitted to statistical analysis with a significance level of p<0.05. Results The Experimental Denervated Group and the Experimental Denervated and Treated Group had cross-sectional area of smaller fiber compared to the Final Control Group. However, there was significant difference between the Experimental Denervated Group and Experimental Denervated and Treated Group, showing that electrical stimulation minimized muscle atrophy. The Experimental Denervated and Treated Group and Initial Control Group showed similar results. Conclusion Electrical stimulation through Russian current acted favorably in maintaining morphology of the cranial tibial muscle that was experimentally denervated, minimizing muscle atrophy.Instituto Israelita de Ensino e Pesquisa Albert Einstein2017-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000100071einstein (São Paulo) v.15 n.1 2017reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/s1679-45082017ao3808info:eu-repo/semantics/openAccessBueno,Cleuber Rodrigo de SouzaPereira,MizaelFavaretto Junior,Idvaldo AparecidoBortoluci,Carlos Henrique FachinSantos,Thais Caroline Pereira dosDias,Daniel VenturaDaré,Letícia RossiRosa Junior,Geraldo Marcoeng2017-10-16T00:00:00Zoai:scielo:S1679-45082017000100071Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2017-10-16T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false |
dc.title.none.fl_str_mv |
Electrical stimulation attenuates morphological alterations and prevents atrophy of the denervated cranial tibial muscle |
title |
Electrical stimulation attenuates morphological alterations and prevents atrophy of the denervated cranial tibial muscle |
spellingShingle |
Electrical stimulation attenuates morphological alterations and prevents atrophy of the denervated cranial tibial muscle Bueno,Cleuber Rodrigo de Souza Electric stimulation/methods Muscle, skeletal Muscular atrophy Muscle denervation Rats |
title_short |
Electrical stimulation attenuates morphological alterations and prevents atrophy of the denervated cranial tibial muscle |
title_full |
Electrical stimulation attenuates morphological alterations and prevents atrophy of the denervated cranial tibial muscle |
title_fullStr |
Electrical stimulation attenuates morphological alterations and prevents atrophy of the denervated cranial tibial muscle |
title_full_unstemmed |
Electrical stimulation attenuates morphological alterations and prevents atrophy of the denervated cranial tibial muscle |
title_sort |
Electrical stimulation attenuates morphological alterations and prevents atrophy of the denervated cranial tibial muscle |
author |
Bueno,Cleuber Rodrigo de Souza |
author_facet |
Bueno,Cleuber Rodrigo de Souza Pereira,Mizael Favaretto Junior,Idvaldo Aparecido Bortoluci,Carlos Henrique Fachin Santos,Thais Caroline Pereira dos Dias,Daniel Ventura Daré,Letícia Rossi Rosa Junior,Geraldo Marco |
author_role |
author |
author2 |
Pereira,Mizael Favaretto Junior,Idvaldo Aparecido Bortoluci,Carlos Henrique Fachin Santos,Thais Caroline Pereira dos Dias,Daniel Ventura Daré,Letícia Rossi Rosa Junior,Geraldo Marco |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Bueno,Cleuber Rodrigo de Souza Pereira,Mizael Favaretto Junior,Idvaldo Aparecido Bortoluci,Carlos Henrique Fachin Santos,Thais Caroline Pereira dos Dias,Daniel Ventura Daré,Letícia Rossi Rosa Junior,Geraldo Marco |
dc.subject.por.fl_str_mv |
Electric stimulation/methods Muscle, skeletal Muscular atrophy Muscle denervation Rats |
topic |
Electric stimulation/methods Muscle, skeletal Muscular atrophy Muscle denervation Rats |
description |
ABSTRACT Objective To investigate if electrical stimulation through Russian current is able to maintain morphology of the cranial tibial muscle of experimentally denervated rats. Methods Thirty-six Wistar rats were divided into four groups: the Initial Control Group, Final Control Group, Experimental Denervated and Treated Group, Experimental Denervated Group. The electrostimulation was performed with a protocol of Russian current applied three times per week, for 45 days. At the end, the animals were euthanized and histological and morphometric analyses were performed. Data were submitted to statistical analysis with a significance level of p<0.05. Results The Experimental Denervated Group and the Experimental Denervated and Treated Group had cross-sectional area of smaller fiber compared to the Final Control Group. However, there was significant difference between the Experimental Denervated Group and Experimental Denervated and Treated Group, showing that electrical stimulation minimized muscle atrophy. The Experimental Denervated and Treated Group and Initial Control Group showed similar results. Conclusion Electrical stimulation through Russian current acted favorably in maintaining morphology of the cranial tibial muscle that was experimentally denervated, minimizing muscle atrophy. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000100071 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000100071 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s1679-45082017ao3808 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
dc.source.none.fl_str_mv |
einstein (São Paulo) v.15 n.1 2017 reponame:Einstein (São Paulo) instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) instacron:IIEPAE |
instname_str |
Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
instacron_str |
IIEPAE |
institution |
IIEPAE |
reponame_str |
Einstein (São Paulo) |
collection |
Einstein (São Paulo) |
repository.name.fl_str_mv |
Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
repository.mail.fl_str_mv |
||revista@einstein.br |
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1752129908749893632 |