Chest computed tomography in the diagnosis of COVID-19 in patients with false negative RT-PCR
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Einstein (São Paulo) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082021000100245 |
Resumo: | ABSTRACT Objective To evaluate the role of chest computed tomography in patients with COVID-19 who presented initial negative result in reverse transcriptase-polymerase chain reaction (RT-PCR). Methods A single-center, retrospective study that evaluated 39 patients with negative RT-PCR for COVID-19, who underwent chest computed tomography and had a final clinical or serological diagnosis of COVID-19. The visual tomographic classification was evaluated according to the Consensus of the Radiological Society of North America and software developed with artificial intelligence for automatic detection of findings and chance estimation of COVID-19. Results In the visual tomographic analysis, only one of them (3%) presented computed tomography classified as negative, 69% were classified as typical and 28% as indeterminate. In the evaluation using the software, only four (about 10%) had a probability of COVID-19 <25%. Conclusion Computed tomography can play an important role in management of suspected cases of COVID-19 with initial negative results in RT-PCR, especially considering those patients outside the ideal window for sample collection for RT-PCR. |
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Chest computed tomography in the diagnosis of COVID-19 in patients with false negative RT-PCRCOVID-19CoronavirusCoronavirus infectionsPneumonia, viralTomography, X-ray computedReverse transcriptase polymerase chain reactionABSTRACT Objective To evaluate the role of chest computed tomography in patients with COVID-19 who presented initial negative result in reverse transcriptase-polymerase chain reaction (RT-PCR). Methods A single-center, retrospective study that evaluated 39 patients with negative RT-PCR for COVID-19, who underwent chest computed tomography and had a final clinical or serological diagnosis of COVID-19. The visual tomographic classification was evaluated according to the Consensus of the Radiological Society of North America and software developed with artificial intelligence for automatic detection of findings and chance estimation of COVID-19. Results In the visual tomographic analysis, only one of them (3%) presented computed tomography classified as negative, 69% were classified as typical and 28% as indeterminate. In the evaluation using the software, only four (about 10%) had a probability of COVID-19 <25%. Conclusion Computed tomography can play an important role in management of suspected cases of COVID-19 with initial negative results in RT-PCR, especially considering those patients outside the ideal window for sample collection for RT-PCR.Instituto Israelita de Ensino e Pesquisa Albert Einstein2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082021000100245einstein (São Paulo) v.19 2021reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.31744/einstein_journal/2021ao6363info:eu-repo/semantics/openAccessFonseca,Eduardo Kaiser Ururahy NunesFerreira,Lorena CarneiroLoureiro,Bruna Melo CoelhoStrabelli,Daniel GiunchettiFarias,Lucas de Pádua Gomes deQueiroz,Gabriel Abrantes deGarcia,José Vitor RassiTeixeira,Renato de FreitasGama,Victor Arcanjo AlmeidaChate,Rodrigo CarusoAssunção Júnior,Antonildes NascimentoSawamura,Márcio Valente YamadaNomura,Cesar Higaeng2021-11-03T00:00:00Zoai:scielo:S1679-45082021000100245Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2021-11-03T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false |
dc.title.none.fl_str_mv |
Chest computed tomography in the diagnosis of COVID-19 in patients with false negative RT-PCR |
title |
Chest computed tomography in the diagnosis of COVID-19 in patients with false negative RT-PCR |
spellingShingle |
Chest computed tomography in the diagnosis of COVID-19 in patients with false negative RT-PCR Fonseca,Eduardo Kaiser Ururahy Nunes COVID-19 Coronavirus Coronavirus infections Pneumonia, viral Tomography, X-ray computed Reverse transcriptase polymerase chain reaction |
title_short |
Chest computed tomography in the diagnosis of COVID-19 in patients with false negative RT-PCR |
title_full |
Chest computed tomography in the diagnosis of COVID-19 in patients with false negative RT-PCR |
title_fullStr |
Chest computed tomography in the diagnosis of COVID-19 in patients with false negative RT-PCR |
title_full_unstemmed |
Chest computed tomography in the diagnosis of COVID-19 in patients with false negative RT-PCR |
title_sort |
Chest computed tomography in the diagnosis of COVID-19 in patients with false negative RT-PCR |
author |
Fonseca,Eduardo Kaiser Ururahy Nunes |
author_facet |
Fonseca,Eduardo Kaiser Ururahy Nunes Ferreira,Lorena Carneiro Loureiro,Bruna Melo Coelho Strabelli,Daniel Giunchetti Farias,Lucas de Pádua Gomes de Queiroz,Gabriel Abrantes de Garcia,José Vitor Rassi Teixeira,Renato de Freitas Gama,Victor Arcanjo Almeida Chate,Rodrigo Caruso Assunção Júnior,Antonildes Nascimento Sawamura,Márcio Valente Yamada Nomura,Cesar Higa |
author_role |
author |
author2 |
Ferreira,Lorena Carneiro Loureiro,Bruna Melo Coelho Strabelli,Daniel Giunchetti Farias,Lucas de Pádua Gomes de Queiroz,Gabriel Abrantes de Garcia,José Vitor Rassi Teixeira,Renato de Freitas Gama,Victor Arcanjo Almeida Chate,Rodrigo Caruso Assunção Júnior,Antonildes Nascimento Sawamura,Márcio Valente Yamada Nomura,Cesar Higa |
author2_role |
author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Fonseca,Eduardo Kaiser Ururahy Nunes Ferreira,Lorena Carneiro Loureiro,Bruna Melo Coelho Strabelli,Daniel Giunchetti Farias,Lucas de Pádua Gomes de Queiroz,Gabriel Abrantes de Garcia,José Vitor Rassi Teixeira,Renato de Freitas Gama,Victor Arcanjo Almeida Chate,Rodrigo Caruso Assunção Júnior,Antonildes Nascimento Sawamura,Márcio Valente Yamada Nomura,Cesar Higa |
dc.subject.por.fl_str_mv |
COVID-19 Coronavirus Coronavirus infections Pneumonia, viral Tomography, X-ray computed Reverse transcriptase polymerase chain reaction |
topic |
COVID-19 Coronavirus Coronavirus infections Pneumonia, viral Tomography, X-ray computed Reverse transcriptase polymerase chain reaction |
description |
ABSTRACT Objective To evaluate the role of chest computed tomography in patients with COVID-19 who presented initial negative result in reverse transcriptase-polymerase chain reaction (RT-PCR). Methods A single-center, retrospective study that evaluated 39 patients with negative RT-PCR for COVID-19, who underwent chest computed tomography and had a final clinical or serological diagnosis of COVID-19. The visual tomographic classification was evaluated according to the Consensus of the Radiological Society of North America and software developed with artificial intelligence for automatic detection of findings and chance estimation of COVID-19. Results In the visual tomographic analysis, only one of them (3%) presented computed tomography classified as negative, 69% were classified as typical and 28% as indeterminate. In the evaluation using the software, only four (about 10%) had a probability of COVID-19 <25%. Conclusion Computed tomography can play an important role in management of suspected cases of COVID-19 with initial negative results in RT-PCR, especially considering those patients outside the ideal window for sample collection for RT-PCR. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082021000100245 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082021000100245 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.31744/einstein_journal/2021ao6363 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
dc.source.none.fl_str_mv |
einstein (São Paulo) v.19 2021 reponame:Einstein (São Paulo) instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) instacron:IIEPAE |
instname_str |
Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
instacron_str |
IIEPAE |
institution |
IIEPAE |
reponame_str |
Einstein (São Paulo) |
collection |
Einstein (São Paulo) |
repository.name.fl_str_mv |
Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
repository.mail.fl_str_mv |
||revista@einstein.br |
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