Retinal changes in solid organ and bone marrow transplantation patients

Detalhes bibliográficos
Autor(a) principal: Malerbi,Fernando Korn
Data de Publicação: 2017
Outros Autores: Teixeira,Sergio Henrique, Hirai,Luis Gustavo Gondo, Matsudo,Nilson Hideo, Carneiro,Adriano Biondi Monteiro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Einstein (São Paulo)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000200123
Resumo: ABSTRACT Objective To evaluate retinal changes in patients who underwent solid organ or bone marrow transplantation. Methods A retrospective analysis of medical records of patients evaluated from February 2009 to December 2016. All patients included underwent funduscopy. Clinical and demographic data regarding transplantation and ophthalmological changes were collected. Results A total of 126 patients were analyzed; of these, 108 underwent transplantation and 18 were in the waiting list. Transplantation modalities were heart, lung, kidney, liver, pancreas, combined pancreas and kidney and bone marrow transplantation. The main pre-transplantation comorbidities were diabetes and arterial hypertension. Of the 108 transplanted patients, 82 (76%) had retinal changes. All patients who underwent pancreas or combined pancreas and kidney transplantation had diabetic retinopathy. The main retinal changes found were diabetic retinopathy, hypertensive retinopathy, retinal vascular occlusions, chorioretinal infections and central serous chorioretinopathy. Conclusion Retinal changes were either related to preexisting conditions, mainly diabetic retinopathy, or developed postoperatively as a complication of the surgical procedure, or as an infection related to the immunosuppressive status, or due to drug toxicity. These patients may present with complex ophthalmological changes and should be carefully evaluated prior to surgery and further followed by an ophthalmologist skilled in the management of diabetic retinopathy and posterior pole infections.
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spelling Retinal changes in solid organ and bone marrow transplantation patientsTransplantationBone marrow transplantationDiabetic retinopathyImmunosuppressionCentral serous chorioretinopathyABSTRACT Objective To evaluate retinal changes in patients who underwent solid organ or bone marrow transplantation. Methods A retrospective analysis of medical records of patients evaluated from February 2009 to December 2016. All patients included underwent funduscopy. Clinical and demographic data regarding transplantation and ophthalmological changes were collected. Results A total of 126 patients were analyzed; of these, 108 underwent transplantation and 18 were in the waiting list. Transplantation modalities were heart, lung, kidney, liver, pancreas, combined pancreas and kidney and bone marrow transplantation. The main pre-transplantation comorbidities were diabetes and arterial hypertension. Of the 108 transplanted patients, 82 (76%) had retinal changes. All patients who underwent pancreas or combined pancreas and kidney transplantation had diabetic retinopathy. The main retinal changes found were diabetic retinopathy, hypertensive retinopathy, retinal vascular occlusions, chorioretinal infections and central serous chorioretinopathy. Conclusion Retinal changes were either related to preexisting conditions, mainly diabetic retinopathy, or developed postoperatively as a complication of the surgical procedure, or as an infection related to the immunosuppressive status, or due to drug toxicity. These patients may present with complex ophthalmological changes and should be carefully evaluated prior to surgery and further followed by an ophthalmologist skilled in the management of diabetic retinopathy and posterior pole infections.Instituto Israelita de Ensino e Pesquisa Albert Einstein2017-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000200123einstein (São Paulo) v.15 n.2 2017reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/s1679-45082017ao3992info:eu-repo/semantics/openAccessMalerbi,Fernando KornTeixeira,Sergio HenriqueHirai,Luis Gustavo GondoMatsudo,Nilson HideoCarneiro,Adriano Biondi Monteiroeng2017-10-16T00:00:00Zoai:scielo:S1679-45082017000200123Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2017-10-16T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false
dc.title.none.fl_str_mv Retinal changes in solid organ and bone marrow transplantation patients
title Retinal changes in solid organ and bone marrow transplantation patients
spellingShingle Retinal changes in solid organ and bone marrow transplantation patients
Malerbi,Fernando Korn
Transplantation
Bone marrow transplantation
Diabetic retinopathy
Immunosuppression
Central serous chorioretinopathy
title_short Retinal changes in solid organ and bone marrow transplantation patients
title_full Retinal changes in solid organ and bone marrow transplantation patients
title_fullStr Retinal changes in solid organ and bone marrow transplantation patients
title_full_unstemmed Retinal changes in solid organ and bone marrow transplantation patients
title_sort Retinal changes in solid organ and bone marrow transplantation patients
author Malerbi,Fernando Korn
author_facet Malerbi,Fernando Korn
Teixeira,Sergio Henrique
Hirai,Luis Gustavo Gondo
Matsudo,Nilson Hideo
Carneiro,Adriano Biondi Monteiro
author_role author
author2 Teixeira,Sergio Henrique
Hirai,Luis Gustavo Gondo
Matsudo,Nilson Hideo
Carneiro,Adriano Biondi Monteiro
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Malerbi,Fernando Korn
Teixeira,Sergio Henrique
Hirai,Luis Gustavo Gondo
Matsudo,Nilson Hideo
Carneiro,Adriano Biondi Monteiro
dc.subject.por.fl_str_mv Transplantation
Bone marrow transplantation
Diabetic retinopathy
Immunosuppression
Central serous chorioretinopathy
topic Transplantation
Bone marrow transplantation
Diabetic retinopathy
Immunosuppression
Central serous chorioretinopathy
description ABSTRACT Objective To evaluate retinal changes in patients who underwent solid organ or bone marrow transplantation. Methods A retrospective analysis of medical records of patients evaluated from February 2009 to December 2016. All patients included underwent funduscopy. Clinical and demographic data regarding transplantation and ophthalmological changes were collected. Results A total of 126 patients were analyzed; of these, 108 underwent transplantation and 18 were in the waiting list. Transplantation modalities were heart, lung, kidney, liver, pancreas, combined pancreas and kidney and bone marrow transplantation. The main pre-transplantation comorbidities were diabetes and arterial hypertension. Of the 108 transplanted patients, 82 (76%) had retinal changes. All patients who underwent pancreas or combined pancreas and kidney transplantation had diabetic retinopathy. The main retinal changes found were diabetic retinopathy, hypertensive retinopathy, retinal vascular occlusions, chorioretinal infections and central serous chorioretinopathy. Conclusion Retinal changes were either related to preexisting conditions, mainly diabetic retinopathy, or developed postoperatively as a complication of the surgical procedure, or as an infection related to the immunosuppressive status, or due to drug toxicity. These patients may present with complex ophthalmological changes and should be carefully evaluated prior to surgery and further followed by an ophthalmologist skilled in the management of diabetic retinopathy and posterior pole infections.
publishDate 2017
dc.date.none.fl_str_mv 2017-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000200123
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000200123
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/s1679-45082017ao3992
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.source.none.fl_str_mv einstein (São Paulo) v.15 n.2 2017
reponame:Einstein (São Paulo)
instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron:IIEPAE
instname_str Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron_str IIEPAE
institution IIEPAE
reponame_str Einstein (São Paulo)
collection Einstein (São Paulo)
repository.name.fl_str_mv Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
repository.mail.fl_str_mv ||revista@einstein.br
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