Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Einstein (São Paulo) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082018000100212 |
Resumo: | Abstract Objective To analyze the combined effects of the silk protein sericin and swimming exercise on histomorphometry of the plantar muscle in Wistar rats. Methods Forty adult rats were randomly allocated into 5 groups comprising 8 animals each, as follows: Control, Injury, Sericin, Swim, and Swim plus Sericin. Three days after crushing of the sciatic nerve the rats in the Swim and Swim plus Sericin Groups were submitted to swimming exercise for 21 days. Rats were then euthanized and the plantar muscle harvested and processed. Results Cross-sectional area, peripheral nuclei and muscle fiber counts, nucleus/fiber ratio and smallest muscle fiber width did not differ significantly between groups. Morphological analysis revealed hypertrophic fibers in the Swim Group and evident muscle damage in the Swim plus Sericin and Injury Groups. The percentage of intramuscular collagen was apparently maintained in the Swim Group compared to remaining groups. Conclusion Combined treatment with sericin and swimming exercise did not improve muscle properties. However, physical exercise alone was effective in maintaining intramuscular connective tissue and preventing progression of deleterious effects of peripheral nerve injury. |
id |
IIEPAE-1_779c5450c8c5b06e6332d05ccbd8d01b |
---|---|
oai_identifier_str |
oai:scielo:S1679-45082018000100212 |
network_acronym_str |
IIEPAE-1 |
network_name_str |
Einstein (São Paulo) |
repository_id_str |
|
spelling |
Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar ratsPeripheral nervesMuscle fibersskeletalExerciseSciatic nerve/injuriesProteinsRatsWistarAbstract Objective To analyze the combined effects of the silk protein sericin and swimming exercise on histomorphometry of the plantar muscle in Wistar rats. Methods Forty adult rats were randomly allocated into 5 groups comprising 8 animals each, as follows: Control, Injury, Sericin, Swim, and Swim plus Sericin. Three days after crushing of the sciatic nerve the rats in the Swim and Swim plus Sericin Groups were submitted to swimming exercise for 21 days. Rats were then euthanized and the plantar muscle harvested and processed. Results Cross-sectional area, peripheral nuclei and muscle fiber counts, nucleus/fiber ratio and smallest muscle fiber width did not differ significantly between groups. Morphological analysis revealed hypertrophic fibers in the Swim Group and evident muscle damage in the Swim plus Sericin and Injury Groups. The percentage of intramuscular collagen was apparently maintained in the Swim Group compared to remaining groups. Conclusion Combined treatment with sericin and swimming exercise did not improve muscle properties. However, physical exercise alone was effective in maintaining intramuscular connective tissue and preventing progression of deleterious effects of peripheral nerve injury.Instituto Israelita de Ensino e Pesquisa Albert Einstein2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082018000100212einstein (São Paulo) v.16 n.1 2018reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/s1679-45082018ao4137info:eu-repo/semantics/openAccessSantana,André JuniorDebastiani,Jean CarlosBuratti,PâmelaPeretti,Ana LuizaKunz,Regina InêsBrancalhão,Rose Meire CostaRibeiro,Lucinéia de Fátima ChaskoTorrejais,Márcia MirandaBertolini,Gladson Ricardo Floreng2018-05-02T00:00:00Zoai:scielo:S1679-45082018000100212Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2018-05-02T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false |
dc.title.none.fl_str_mv |
Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
title |
Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
spellingShingle |
Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats Santana,André Junior Peripheral nerves Muscle fibers skeletal Exercise Sciatic nerve/injuries Proteins Rats Wistar |
title_short |
Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
title_full |
Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
title_fullStr |
Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
title_full_unstemmed |
Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
title_sort |
Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats |
author |
Santana,André Junior |
author_facet |
Santana,André Junior Debastiani,Jean Carlos Buratti,Pâmela Peretti,Ana Luiza Kunz,Regina Inês Brancalhão,Rose Meire Costa Ribeiro,Lucinéia de Fátima Chasko Torrejais,Márcia Miranda Bertolini,Gladson Ricardo Flor |
author_role |
author |
author2 |
Debastiani,Jean Carlos Buratti,Pâmela Peretti,Ana Luiza Kunz,Regina Inês Brancalhão,Rose Meire Costa Ribeiro,Lucinéia de Fátima Chasko Torrejais,Márcia Miranda Bertolini,Gladson Ricardo Flor |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Santana,André Junior Debastiani,Jean Carlos Buratti,Pâmela Peretti,Ana Luiza Kunz,Regina Inês Brancalhão,Rose Meire Costa Ribeiro,Lucinéia de Fátima Chasko Torrejais,Márcia Miranda Bertolini,Gladson Ricardo Flor |
dc.subject.por.fl_str_mv |
Peripheral nerves Muscle fibers skeletal Exercise Sciatic nerve/injuries Proteins Rats Wistar |
topic |
Peripheral nerves Muscle fibers skeletal Exercise Sciatic nerve/injuries Proteins Rats Wistar |
description |
Abstract Objective To analyze the combined effects of the silk protein sericin and swimming exercise on histomorphometry of the plantar muscle in Wistar rats. Methods Forty adult rats were randomly allocated into 5 groups comprising 8 animals each, as follows: Control, Injury, Sericin, Swim, and Swim plus Sericin. Three days after crushing of the sciatic nerve the rats in the Swim and Swim plus Sericin Groups were submitted to swimming exercise for 21 days. Rats were then euthanized and the plantar muscle harvested and processed. Results Cross-sectional area, peripheral nuclei and muscle fiber counts, nucleus/fiber ratio and smallest muscle fiber width did not differ significantly between groups. Morphological analysis revealed hypertrophic fibers in the Swim Group and evident muscle damage in the Swim plus Sericin and Injury Groups. The percentage of intramuscular collagen was apparently maintained in the Swim Group compared to remaining groups. Conclusion Combined treatment with sericin and swimming exercise did not improve muscle properties. However, physical exercise alone was effective in maintaining intramuscular connective tissue and preventing progression of deleterious effects of peripheral nerve injury. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082018000100212 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082018000100212 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s1679-45082018ao4137 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
publisher.none.fl_str_mv |
Instituto Israelita de Ensino e Pesquisa Albert Einstein |
dc.source.none.fl_str_mv |
einstein (São Paulo) v.16 n.1 2018 reponame:Einstein (São Paulo) instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) instacron:IIEPAE |
instname_str |
Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
instacron_str |
IIEPAE |
institution |
IIEPAE |
reponame_str |
Einstein (São Paulo) |
collection |
Einstein (São Paulo) |
repository.name.fl_str_mv |
Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) |
repository.mail.fl_str_mv |
||revista@einstein.br |
_version_ |
1752129909192392704 |