The role of thromboelastometry in the assessment and treatment of coagulopathy in liver transplant patients

Detalhes bibliográficos
Autor(a) principal: Zamper,Raffael Pereira Cezar
Data de Publicação: 2017
Outros Autores: Amorim,Thiago Chaves, Costa,Luiz Guilherme Villares da, Takaoka,Flávio, Serpa Neto,Ary
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Einstein (São Paulo)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000200243
Resumo: ABSTRACT Perioperative monitoring of coagulation is vital to assess bleeding risks, diagnose deficiencies associated with hemorrhage, and guide hemostatic therapy in major surgical procedures, such as liver transplantation. Routine static tests demand long turnaround time and do not assess platelet function; they are determined on plasma at a standard temperature of 37°C; hence these tests are ill-suited for intraoperative use. In contrast, methods which evaluate the viscoelastic properties of whole blood, such as thromboelastogram and rotational thromboelastometry, provide rapid qualitative coagulation assessment and appropriate guidance for transfusion therapy. These are promising tools for the assessment and treatment of hyper- and hypocoagulable states associated with bleeding in liver transplantation. When combined with traditional tests and objective assessment of the surgical field, this information provides ideal guidance for transfusion strategies, with potential improvement of patient outcomes.
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spelling The role of thromboelastometry in the assessment and treatment of coagulopathy in liver transplant patientsTransplantationLiver transplantationBlood coagulationThrombelastographyHemorrhageBlood transfusionABSTRACT Perioperative monitoring of coagulation is vital to assess bleeding risks, diagnose deficiencies associated with hemorrhage, and guide hemostatic therapy in major surgical procedures, such as liver transplantation. Routine static tests demand long turnaround time and do not assess platelet function; they are determined on plasma at a standard temperature of 37°C; hence these tests are ill-suited for intraoperative use. In contrast, methods which evaluate the viscoelastic properties of whole blood, such as thromboelastogram and rotational thromboelastometry, provide rapid qualitative coagulation assessment and appropriate guidance for transfusion therapy. These are promising tools for the assessment and treatment of hyper- and hypocoagulable states associated with bleeding in liver transplantation. When combined with traditional tests and objective assessment of the surgical field, this information provides ideal guidance for transfusion strategies, with potential improvement of patient outcomes.Instituto Israelita de Ensino e Pesquisa Albert Einstein2017-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000200243einstein (São Paulo) v.15 n.2 2017reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/s1679-45082017md3903info:eu-repo/semantics/openAccessZamper,Raffael Pereira CezarAmorim,Thiago ChavesCosta,Luiz Guilherme Villares daTakaoka,FlávioSerpa Neto,Aryeng2017-10-16T00:00:00Zoai:scielo:S1679-45082017000200243Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2017-10-16T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false
dc.title.none.fl_str_mv The role of thromboelastometry in the assessment and treatment of coagulopathy in liver transplant patients
title The role of thromboelastometry in the assessment and treatment of coagulopathy in liver transplant patients
spellingShingle The role of thromboelastometry in the assessment and treatment of coagulopathy in liver transplant patients
Zamper,Raffael Pereira Cezar
Transplantation
Liver transplantation
Blood coagulation
Thrombelastography
Hemorrhage
Blood transfusion
title_short The role of thromboelastometry in the assessment and treatment of coagulopathy in liver transplant patients
title_full The role of thromboelastometry in the assessment and treatment of coagulopathy in liver transplant patients
title_fullStr The role of thromboelastometry in the assessment and treatment of coagulopathy in liver transplant patients
title_full_unstemmed The role of thromboelastometry in the assessment and treatment of coagulopathy in liver transplant patients
title_sort The role of thromboelastometry in the assessment and treatment of coagulopathy in liver transplant patients
author Zamper,Raffael Pereira Cezar
author_facet Zamper,Raffael Pereira Cezar
Amorim,Thiago Chaves
Costa,Luiz Guilherme Villares da
Takaoka,Flávio
Serpa Neto,Ary
author_role author
author2 Amorim,Thiago Chaves
Costa,Luiz Guilherme Villares da
Takaoka,Flávio
Serpa Neto,Ary
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Zamper,Raffael Pereira Cezar
Amorim,Thiago Chaves
Costa,Luiz Guilherme Villares da
Takaoka,Flávio
Serpa Neto,Ary
dc.subject.por.fl_str_mv Transplantation
Liver transplantation
Blood coagulation
Thrombelastography
Hemorrhage
Blood transfusion
topic Transplantation
Liver transplantation
Blood coagulation
Thrombelastography
Hemorrhage
Blood transfusion
description ABSTRACT Perioperative monitoring of coagulation is vital to assess bleeding risks, diagnose deficiencies associated with hemorrhage, and guide hemostatic therapy in major surgical procedures, such as liver transplantation. Routine static tests demand long turnaround time and do not assess platelet function; they are determined on plasma at a standard temperature of 37°C; hence these tests are ill-suited for intraoperative use. In contrast, methods which evaluate the viscoelastic properties of whole blood, such as thromboelastogram and rotational thromboelastometry, provide rapid qualitative coagulation assessment and appropriate guidance for transfusion therapy. These are promising tools for the assessment and treatment of hyper- and hypocoagulable states associated with bleeding in liver transplantation. When combined with traditional tests and objective assessment of the surgical field, this information provides ideal guidance for transfusion strategies, with potential improvement of patient outcomes.
publishDate 2017
dc.date.none.fl_str_mv 2017-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000200243
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000200243
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/s1679-45082017md3903
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.source.none.fl_str_mv einstein (São Paulo) v.15 n.2 2017
reponame:Einstein (São Paulo)
instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
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instname_str Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
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institution IIEPAE
reponame_str Einstein (São Paulo)
collection Einstein (São Paulo)
repository.name.fl_str_mv Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
repository.mail.fl_str_mv ||revista@einstein.br
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