Clinical characteristics and long-term progression of young patients with acute coronary syndrome in Brazil

Detalhes bibliográficos
Autor(a) principal: Soeiro,Alexandre de Matos
Data de Publicação: 2015
Outros Autores: Fernandes,Felipe Lourenço, Soeiro,Maria Carolina Feres de Almeida, Serrano Jr,Carlos Vicente, Oliveira Jr,Múcio Tavares de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Einstein (São Paulo)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000300370
Resumo: Objective In Brazil, there are few descriptions in the literature on the angiographic pattern and clinical characteristics of young patients with acute coronary syndrome, despite the evident number of cases in the population. The objective of this study was to evaluate which clinical characteristics are most closely related to the acute coronary syndrome in young patients, and what long-term outcomes are in this population.Methods This is a prospective observational study with 268 patients aged under 55 years with acute coronary syndrome, carried out between May 2010 and May 2013. Data were obtained on demographics, laboratory test and angiography results, and the coronary treatment adopted. Statistical analysis was presented as percentages and absolute values.Results Approximately 57% were men and the median age was 50 years (30 to 55). The main risk factors were arterial hypertension (68%), smoking (67%), and dyslipidemia (43%). Typical pain was present in 90% of patients. In young individuals, 25.7% showed ST segment elevation. Approximately 56.5% of patients presented with a single-vessel angiographic pattern. About 7.1% were submitted to coronary bypass surgery, and 42.1% to percutaneous coronary angioplasty. Intrahospital mortality was 1.5%, and the combined event rate (cerebrovascular accident/stroke, cardiogenic shock, reinfarction, and arrhythmias) was 13.8%. After a mean follow-up of 10 months, mortality was 9.8%, while 25.4% of the patients had new ischemic events, and 37.3% required readmission to hospital.Conclusion In the short-term, young patients presented with mortality rates below what was expected when compared to the rates noted in other studies. However, there was a significant increase in the number of events in the 10-month follow-up.
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spelling Clinical characteristics and long-term progression of young patients with acute coronary syndrome in BrazilAdultAcute coronary syndromeMyocardial infarctionBrazilObjective In Brazil, there are few descriptions in the literature on the angiographic pattern and clinical characteristics of young patients with acute coronary syndrome, despite the evident number of cases in the population. The objective of this study was to evaluate which clinical characteristics are most closely related to the acute coronary syndrome in young patients, and what long-term outcomes are in this population.Methods This is a prospective observational study with 268 patients aged under 55 years with acute coronary syndrome, carried out between May 2010 and May 2013. Data were obtained on demographics, laboratory test and angiography results, and the coronary treatment adopted. Statistical analysis was presented as percentages and absolute values.Results Approximately 57% were men and the median age was 50 years (30 to 55). The main risk factors were arterial hypertension (68%), smoking (67%), and dyslipidemia (43%). Typical pain was present in 90% of patients. In young individuals, 25.7% showed ST segment elevation. Approximately 56.5% of patients presented with a single-vessel angiographic pattern. About 7.1% were submitted to coronary bypass surgery, and 42.1% to percutaneous coronary angioplasty. Intrahospital mortality was 1.5%, and the combined event rate (cerebrovascular accident/stroke, cardiogenic shock, reinfarction, and arrhythmias) was 13.8%. After a mean follow-up of 10 months, mortality was 9.8%, while 25.4% of the patients had new ischemic events, and 37.3% required readmission to hospital.Conclusion In the short-term, young patients presented with mortality rates below what was expected when compared to the rates noted in other studies. However, there was a significant increase in the number of events in the 10-month follow-up.Instituto Israelita de Ensino e Pesquisa Albert Einstein2015-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000300370einstein (São Paulo) v.13 n.3 2015reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/S1679-45082015AO3381info:eu-repo/semantics/openAccessSoeiro,Alexandre de MatosFernandes,Felipe LourençoSoeiro,Maria Carolina Feres de AlmeidaSerrano Jr,Carlos VicenteOliveira Jr,Múcio Tavares deeng2015-10-13T00:00:00Zoai:scielo:S1679-45082015000300370Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2015-10-13T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false
dc.title.none.fl_str_mv Clinical characteristics and long-term progression of young patients with acute coronary syndrome in Brazil
title Clinical characteristics and long-term progression of young patients with acute coronary syndrome in Brazil
spellingShingle Clinical characteristics and long-term progression of young patients with acute coronary syndrome in Brazil
Soeiro,Alexandre de Matos
Adult
Acute coronary syndrome
Myocardial infarction
Brazil
title_short Clinical characteristics and long-term progression of young patients with acute coronary syndrome in Brazil
title_full Clinical characteristics and long-term progression of young patients with acute coronary syndrome in Brazil
title_fullStr Clinical characteristics and long-term progression of young patients with acute coronary syndrome in Brazil
title_full_unstemmed Clinical characteristics and long-term progression of young patients with acute coronary syndrome in Brazil
title_sort Clinical characteristics and long-term progression of young patients with acute coronary syndrome in Brazil
author Soeiro,Alexandre de Matos
author_facet Soeiro,Alexandre de Matos
Fernandes,Felipe Lourenço
Soeiro,Maria Carolina Feres de Almeida
Serrano Jr,Carlos Vicente
Oliveira Jr,Múcio Tavares de
author_role author
author2 Fernandes,Felipe Lourenço
Soeiro,Maria Carolina Feres de Almeida
Serrano Jr,Carlos Vicente
Oliveira Jr,Múcio Tavares de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Soeiro,Alexandre de Matos
Fernandes,Felipe Lourenço
Soeiro,Maria Carolina Feres de Almeida
Serrano Jr,Carlos Vicente
Oliveira Jr,Múcio Tavares de
dc.subject.por.fl_str_mv Adult
Acute coronary syndrome
Myocardial infarction
Brazil
topic Adult
Acute coronary syndrome
Myocardial infarction
Brazil
description Objective In Brazil, there are few descriptions in the literature on the angiographic pattern and clinical characteristics of young patients with acute coronary syndrome, despite the evident number of cases in the population. The objective of this study was to evaluate which clinical characteristics are most closely related to the acute coronary syndrome in young patients, and what long-term outcomes are in this population.Methods This is a prospective observational study with 268 patients aged under 55 years with acute coronary syndrome, carried out between May 2010 and May 2013. Data were obtained on demographics, laboratory test and angiography results, and the coronary treatment adopted. Statistical analysis was presented as percentages and absolute values.Results Approximately 57% were men and the median age was 50 years (30 to 55). The main risk factors were arterial hypertension (68%), smoking (67%), and dyslipidemia (43%). Typical pain was present in 90% of patients. In young individuals, 25.7% showed ST segment elevation. Approximately 56.5% of patients presented with a single-vessel angiographic pattern. About 7.1% were submitted to coronary bypass surgery, and 42.1% to percutaneous coronary angioplasty. Intrahospital mortality was 1.5%, and the combined event rate (cerebrovascular accident/stroke, cardiogenic shock, reinfarction, and arrhythmias) was 13.8%. After a mean follow-up of 10 months, mortality was 9.8%, while 25.4% of the patients had new ischemic events, and 37.3% required readmission to hospital.Conclusion In the short-term, young patients presented with mortality rates below what was expected when compared to the rates noted in other studies. However, there was a significant increase in the number of events in the 10-month follow-up.
publishDate 2015
dc.date.none.fl_str_mv 2015-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015000300370
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1679-45082015AO3381
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.source.none.fl_str_mv einstein (São Paulo) v.13 n.3 2015
reponame:Einstein (São Paulo)
instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
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reponame_str Einstein (São Paulo)
collection Einstein (São Paulo)
repository.name.fl_str_mv Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
repository.mail.fl_str_mv ||revista@einstein.br
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