Insuficiência hepática na hanseníase devida a amiloidose
Autor(a) principal: | |
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Data de Publicação: | 1976 |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Hansenologia Internationalis (Online) |
Texto Completo: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/36044 |
Resumo: | A case of hanseniasis with uncommonly severe secondary amyloidosis is reported and discussed. Clinical, laboratory and postmortem findings show large involvement of the liver and hepatic deficiency, the principal cause of death. Hepatic deficiency with portal hypertension has been described in primaryamyloidosis, but in the secondary type, as in this case, it has only been reported once, by Manzi et al (1071). It is attributed to pro tracted long term hanseniasis, hansenw reactions of the erythema nodosum type and osteomyelitis related to plantar ulcerations, all those conditions leading to an excess of antigenicstimulation and debilitation of the humoral response. Although 25% of deaths due to hansensasis in the West are caused by amyloidosis of the kidneys causing a nephrotie syndrome, in this case it did not lead to serious renal dysfunction. |
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Insuficiência hepática na hanseníase devida a amiloidoseA case of hanseniasis with uncommonly severe secondary amyloidosis is reported and discussed. Clinical, laboratory and postmortem findings show large involvement of the liver and hepatic deficiency, the principal cause of death. Hepatic deficiency with portal hypertension has been described in primaryamyloidosis, but in the secondary type, as in this case, it has only been reported once, by Manzi et al (1071). It is attributed to pro tracted long term hanseniasis, hansenw reactions of the erythema nodosum type and osteomyelitis related to plantar ulcerations, all those conditions leading to an excess of antigenicstimulation and debilitation of the humoral response. Although 25% of deaths due to hansensasis in the West are caused by amyloidosis of the kidneys causing a nephrotie syndrome, in this case it did not lead to serious renal dysfunction..Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1976-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3604410.47878/hi.1976.v1.36044Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 1 No. 2 (1976); 202-206Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 1 n. 2 (1976); 202-2061982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/36044/34349https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOPROMOLLA, D.V.A.2023-11-30T14:06:58Zoai:ojs.periodicos.saude.sp.gov.br:article/36044Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-11-30T14:06:58Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false |
dc.title.none.fl_str_mv |
Insuficiência hepática na hanseníase devida a amiloidose |
title |
Insuficiência hepática na hanseníase devida a amiloidose |
spellingShingle |
Insuficiência hepática na hanseníase devida a amiloidose OPROMOLLA, D.V.A. |
title_short |
Insuficiência hepática na hanseníase devida a amiloidose |
title_full |
Insuficiência hepática na hanseníase devida a amiloidose |
title_fullStr |
Insuficiência hepática na hanseníase devida a amiloidose |
title_full_unstemmed |
Insuficiência hepática na hanseníase devida a amiloidose |
title_sort |
Insuficiência hepática na hanseníase devida a amiloidose |
author |
OPROMOLLA, D.V.A. |
author_facet |
OPROMOLLA, D.V.A. |
author_role |
author |
dc.contributor.author.fl_str_mv |
OPROMOLLA, D.V.A. |
description |
A case of hanseniasis with uncommonly severe secondary amyloidosis is reported and discussed. Clinical, laboratory and postmortem findings show large involvement of the liver and hepatic deficiency, the principal cause of death. Hepatic deficiency with portal hypertension has been described in primaryamyloidosis, but in the secondary type, as in this case, it has only been reported once, by Manzi et al (1071). It is attributed to pro tracted long term hanseniasis, hansenw reactions of the erythema nodosum type and osteomyelitis related to plantar ulcerations, all those conditions leading to an excess of antigenicstimulation and debilitation of the humoral response. Although 25% of deaths due to hansensasis in the West are caused by amyloidosis of the kidneys causing a nephrotie syndrome, in this case it did not lead to serious renal dysfunction. |
publishDate |
1976 |
dc.date.none.fl_str_mv |
1976-11-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36044 10.47878/hi.1976.v1.36044 |
url |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36044 |
identifier_str_mv |
10.47878/hi.1976.v1.36044 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36044/34349 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
dc.source.none.fl_str_mv |
Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 1 No. 2 (1976); 202-206 Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 1 n. 2 (1976); 202-206 1982-5161 reponame:Hansenologia Internationalis (Online) instname:Instituto Lauro de Souza Lima (ILSL) instacron:ILSL |
instname_str |
Instituto Lauro de Souza Lima (ILSL) |
instacron_str |
ILSL |
institution |
ILSL |
reponame_str |
Hansenologia Internationalis (Online) |
collection |
Hansenologia Internationalis (Online) |
repository.name.fl_str_mv |
Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL) |
repository.mail.fl_str_mv |
hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br |
_version_ |
1796797580187795456 |