Identification of a patient with multibacillary leprosy using the serological test (LID) in active search actions: a case report

Detalhes bibliográficos
Autor(a) principal: Leite, Heloine Martins
Data de Publicação: 2023
Outros Autores: Pinheiro, Marcos Daniel Silva, Santos, Daisy Cristina Monteiro dos, Campos, Karolina Dias, Oliveira, Lorena Bruna Pereira de, Fraga, Lucia Alves de Oliveira
Tipo de documento: Artigo
Idioma: por
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/39317
Resumo: Leprosy is a chronic and infectious disease caused by Mycobacterium leprae (M. leprae). It has high infectivity and low pathogenicity. The aim of this study was to report the identification of a patient with multibacillary leprosy using the serological test (LID) during an active search. A 54-year-old male patient, living in Governador Valadares, Minas Gerais, Brazil, from the active search of the LeprosyResearch Center (NuPqHans/UFJF-GV), presented a positive serological test for recombinant bacillus proteins (ML0405/ML2331). He was referred to the Reference Center for Endemic Diseases and Special Programs (CREDENPES), complaining of skin lesions and nodules all over his body, and reported a history of head trauma, occasional dizziness, numbness in his feet, and nosebleeds. The patient presented positive bacilloscopy and biopsy results, concluding the diagnosis of multibacillary leprosy and receiving the indicated multidrug therapy. After three months of treatment, there was a reduction in the area/diameter of the lesions on the abdomen, indicating the effectiveness of the treatment. The positive result of the serological test (LID) allowed the identification of a multibacillary patient, who until then had not been diagnosed with leprosy. In addition, the use of the LID serological test in active search activities in endemic areas for early diagnosis can contribute to the zero-leprosy concept stipulated by the World Health Organization.
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spelling Identification of a patient with multibacillary leprosy using the serological test (LID) in active search actions: a case report Identificación de un paciente con lepra multibacilar mediante pruebas serológicas (LID) en acciones de búsqueda activa: informe de un casoIdentificação de um paciente com hanseníase multibacilar por meio do teste sorológico (LID) em ações de busca ativa: um relato de casoHanseníaseDiagnósticoSorologiaLeprosyDiagnosisSerologyLepraDiagnósticoSerologíaLeprosy is a chronic and infectious disease caused by Mycobacterium leprae (M. leprae). It has high infectivity and low pathogenicity. The aim of this study was to report the identification of a patient with multibacillary leprosy using the serological test (LID) during an active search. A 54-year-old male patient, living in Governador Valadares, Minas Gerais, Brazil, from the active search of the LeprosyResearch Center (NuPqHans/UFJF-GV), presented a positive serological test for recombinant bacillus proteins (ML0405/ML2331). He was referred to the Reference Center for Endemic Diseases and Special Programs (CREDENPES), complaining of skin lesions and nodules all over his body, and reported a history of head trauma, occasional dizziness, numbness in his feet, and nosebleeds. The patient presented positive bacilloscopy and biopsy results, concluding the diagnosis of multibacillary leprosy and receiving the indicated multidrug therapy. After three months of treatment, there was a reduction in the area/diameter of the lesions on the abdomen, indicating the effectiveness of the treatment. The positive result of the serological test (LID) allowed the identification of a multibacillary patient, who until then had not been diagnosed with leprosy. In addition, the use of the LID serological test in active search activities in endemic areas for early diagnosis can contribute to the zero-leprosy concept stipulated by the World Health Organization.La lepra es una enfermedad infecciosa crónica causada por Mycobacterium leprae (M. leprae). Tiene una alta infectividad y una baja patogenicidad. El objetivo deste estudio fue relatar la identificación de un paciente con lepra multibacilar utilizando la prueba serológica (LID) durante una acción de búsqueda activa. Un paciente masculino de 54 años, residente en Governador Valadares-MG, proveniente de la búsqueda activa del Núcleo de Pesquisa em Hansenologia (NuPqHans/ UFJF-GV), presentó pruebla serológica positiva para la proteína recombinante del bacilo (ML0405/ML2331). Fui remitido al Centro de Referencia de Enfermedades Endémicas y Programas Especiales (CREDENPES), quejándose de lesiones cutáneas y nódulos por todo el cuerpo, refirió antecedentes de traumatismo craneoencefálico, mareos ocasionales, entumecimiento de los pies y hemorragia nasal. El paciente presentó resultados positivos de baciloscopia y biopsia, concluyéndose el diagnóstico de lepra multibacilar, recibiendo la terapia multimedicamentosa indicada. Después de tres meses de tratamiento hubo una reducción del área y diámetro de las lesiones en el abdomen, indicando la eficacia del tratamiento. El resultado positivo de la prueba serológica, permitió identificar a un paciente multibacilar que hasta entonces no había sido diagnosticado de lepra. Además, el uso de la prueba serológica LID en actividades de búsqueda activa en zonas endémicas para el diagnóstico precoz puede contribuir al concepto de lepra cero estipulado por la Organización Mundial de la Salud.A hanseníase é uma doença crônica e infectocontagiosa causada pelo Mycobacterium leprae (M. leprae). Apresenta alta infectividade e baixa patogenicidade. O estudo teve como objetivo relatar a identificação de um paciente com hanseníase multibacilar através do teste sorológico (LID) em ação de busca ativa. Paciente do sexo masculino, 54 anos, residente em Governador Valadares, Minas Gerais, Brasil, proveniente da busca ativa do Núcleo de Pesquisa em Hansenologia (NuPqHans/UFJF-GV), apresentou teste sorológico positivo para proteínas recombinantes do bacilo (ML0405/ML2331). Encaminhado ao Centro de Referência de Doenças Endêmicas e Programas Especiais (CREDENPES), queixando-se de lesões na pele e nódulos pelo corpo, relatou histórico de traumas na cabeça, tonturas ocasionais, dormência nos pés e sangramento nasal. O paciente apresentou resultados de baciloscopia e biopsia positivos, concluindo o diagnóstico de hanseníase multibacilar, recebendo poliquimioterapia indicada. Após três meses de tratamento observou-se redução na área/diâmetro das lesões do abdômen, indicando a eficácia do tratamento. O resultado positivo do teste sorológico, permitiu a identificação de um paciente multibacilar, até então sem diagnóstico de hanseníase. Ademais, a utilização do teste sorológico LID nas atividades de busca ativa em áreas endêmicas para realização do diagnóstico precoce pode contribuir para o conceito zero hanseníase estipulado pela Organização Mundial da Saúde.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo2023-11-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3931710.47878/hi.2023.v48.39317Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 48 (2023); 1-7Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 48 (2023); 1-71982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/39317/37774Copyright (c) 2023 Heloine Martins Leite, Marcos Daniel Silva Pinheiro, Daisy Cristina Monteiro dos Santos, Karolina Dias Campos, Lorena Bruna Pereira de Oliveira, Lucia Alves de Oliveira Fragahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessLeite, Heloine MartinsPinheiro, Marcos Daniel SilvaSantos, Daisy Cristina Monteiro dosCampos, Karolina DiasOliveira, Lorena Bruna Pereira deFraga, Lucia Alves de Oliveira2023-12-15T16:54:27Zoai:ojs.periodicos.saude.sp.gov.br:article/39317Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-12-15T16:54:27Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Identification of a patient with multibacillary leprosy using the serological test (LID) in active search actions: a case report
Identificación de un paciente con lepra multibacilar mediante pruebas serológicas (LID) en acciones de búsqueda activa: informe de un caso
Identificação de um paciente com hanseníase multibacilar por meio do teste sorológico (LID) em ações de busca ativa: um relato de caso
title Identification of a patient with multibacillary leprosy using the serological test (LID) in active search actions: a case report
spellingShingle Identification of a patient with multibacillary leprosy using the serological test (LID) in active search actions: a case report
Leite, Heloine Martins
Hanseníase
Diagnóstico
Sorologia
Leprosy
Diagnosis
Serology
Lepra
Diagnóstico
Serología
title_short Identification of a patient with multibacillary leprosy using the serological test (LID) in active search actions: a case report
title_full Identification of a patient with multibacillary leprosy using the serological test (LID) in active search actions: a case report
title_fullStr Identification of a patient with multibacillary leprosy using the serological test (LID) in active search actions: a case report
title_full_unstemmed Identification of a patient with multibacillary leprosy using the serological test (LID) in active search actions: a case report
title_sort Identification of a patient with multibacillary leprosy using the serological test (LID) in active search actions: a case report
author Leite, Heloine Martins
author_facet Leite, Heloine Martins
Pinheiro, Marcos Daniel Silva
Santos, Daisy Cristina Monteiro dos
Campos, Karolina Dias
Oliveira, Lorena Bruna Pereira de
Fraga, Lucia Alves de Oliveira
author_role author
author2 Pinheiro, Marcos Daniel Silva
Santos, Daisy Cristina Monteiro dos
Campos, Karolina Dias
Oliveira, Lorena Bruna Pereira de
Fraga, Lucia Alves de Oliveira
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Leite, Heloine Martins
Pinheiro, Marcos Daniel Silva
Santos, Daisy Cristina Monteiro dos
Campos, Karolina Dias
Oliveira, Lorena Bruna Pereira de
Fraga, Lucia Alves de Oliveira
dc.subject.por.fl_str_mv Hanseníase
Diagnóstico
Sorologia
Leprosy
Diagnosis
Serology
Lepra
Diagnóstico
Serología
topic Hanseníase
Diagnóstico
Sorologia
Leprosy
Diagnosis
Serology
Lepra
Diagnóstico
Serología
description Leprosy is a chronic and infectious disease caused by Mycobacterium leprae (M. leprae). It has high infectivity and low pathogenicity. The aim of this study was to report the identification of a patient with multibacillary leprosy using the serological test (LID) during an active search. A 54-year-old male patient, living in Governador Valadares, Minas Gerais, Brazil, from the active search of the LeprosyResearch Center (NuPqHans/UFJF-GV), presented a positive serological test for recombinant bacillus proteins (ML0405/ML2331). He was referred to the Reference Center for Endemic Diseases and Special Programs (CREDENPES), complaining of skin lesions and nodules all over his body, and reported a history of head trauma, occasional dizziness, numbness in his feet, and nosebleeds. The patient presented positive bacilloscopy and biopsy results, concluding the diagnosis of multibacillary leprosy and receiving the indicated multidrug therapy. After three months of treatment, there was a reduction in the area/diameter of the lesions on the abdomen, indicating the effectiveness of the treatment. The positive result of the serological test (LID) allowed the identification of a multibacillary patient, who until then had not been diagnosed with leprosy. In addition, the use of the LID serological test in active search activities in endemic areas for early diagnosis can contribute to the zero-leprosy concept stipulated by the World Health Organization.
publishDate 2023
dc.date.none.fl_str_mv 2023-11-28
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/39317
10.47878/hi.2023.v48.39317
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/39317
identifier_str_mv 10.47878/hi.2023.v48.39317
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/39317/37774
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 48 (2023); 1-7
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 48 (2023); 1-7
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
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