Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon

Detalhes bibliográficos
Autor(a) principal: Cunha, Maria Heliana Chaves Monteiro da
Data de Publicação: 2008
Outros Autores: Macedo, Geraldo Mariano Moraes de, Batista, Keila de Nazaré Madureira, Xavier, Marilia Brasil, Neto, Simone de Sá, Nascimento, Francisca Souza do Nascimento e
Tipo de documento: Artigo
Idioma: por
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/36237
Resumo: Mycobacterium leprae (hansen’s baccillus) displays special immunogenic properties responsible by thehigh incapacitating power of leprae. The aims of this study were to determine the clinical-epidemic profileof multibacillar leprosum patients according to madri’s classification, correlate the baciloscopic index with the amount of nerve trunks affected by the classic neuritisprior and post-treatment, and correlate the inability degree of this patient with the clinical form at entrance and outcome. Medical records from 158 selected subjects with multibacilar leprosy from the center of reference in sanitary dermatology dr. Marcelo cândia, in marituba, pará, brazil were accessed to evaluate the baciloscopic and neurological exam. . Fifth two percent of the patients were in the range of 15 to 54 years, 80.4% Were male, 80% reach outcome for cure, and 84% were new cases. The predominant clinical form was dimorfa, comprising 68% of the cases. The virchowian form (mhv) was present in the majority of subjects with degree ii of incapacity, the presence of degree zero of incapacity was statistically significant in the dimorfa form (mhd), whose subjects displayed around 2.69 Fold more chance of evolving with neuritis symptoms than mhv. The most affected peripheric nerves at the moment and during the diagnosis were: tibia posterior, ulnar, fibula, and the to median nerve. In conclusion, mhv is at greater potential to develop degree ii of incapacity, whereas mhd barriers more frequently evolve to neuritis, and there is no difference among the nervous trunks affected in regard to the bacterious index.
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spelling Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazonAvaliação clínico-epidemiológica em pacientes multibacilares em uma unidade de referência de hansenologia da amazôniahanseníase multibacilarneurites clássicastroncos nervosos afetadosgrau de incapacidademultibacillar leprosyclassic neuritisaffected nerve trunksinability degreeMycobacterium leprae (hansen’s baccillus) displays special immunogenic properties responsible by thehigh incapacitating power of leprae. The aims of this study were to determine the clinical-epidemic profileof multibacillar leprosum patients according to madri’s classification, correlate the baciloscopic index with the amount of nerve trunks affected by the classic neuritisprior and post-treatment, and correlate the inability degree of this patient with the clinical form at entrance and outcome. Medical records from 158 selected subjects with multibacilar leprosy from the center of reference in sanitary dermatology dr. Marcelo cândia, in marituba, pará, brazil were accessed to evaluate the baciloscopic and neurological exam. . Fifth two percent of the patients were in the range of 15 to 54 years, 80.4% Were male, 80% reach outcome for cure, and 84% were new cases. The predominant clinical form was dimorfa, comprising 68% of the cases. The virchowian form (mhv) was present in the majority of subjects with degree ii of incapacity, the presence of degree zero of incapacity was statistically significant in the dimorfa form (mhd), whose subjects displayed around 2.69 Fold more chance of evolving with neuritis symptoms than mhv. The most affected peripheric nerves at the moment and during the diagnosis were: tibia posterior, ulnar, fibula, and the to median nerve. In conclusion, mhv is at greater potential to develop degree ii of incapacity, whereas mhd barriers more frequently evolve to neuritis, and there is no difference among the nervous trunks affected in regard to the bacterious index.O mycobacterium leprae (bacilo de hansen) possui propriedades imunogênicas especiais, responsáveis pelo alto poder incapacitante da hanseníase. Objetivou-se estudar o perfil clínico-epidemiológico de pacientes hansenianos multibacilares, de acordo com a classificação de madri, correlacionar o índice baciloscópico com o número de troncos afetados pela neurite franca no início e término do tratamento, correlacionar o grau de incapacidade com a forma clínica, à entrada e à saída desses pacientes. Selecionaram-se 158 prontuários de pacientes diagnosticados com hanseníase multibacilar, avaliados pelo exame baciloscópico e neurológico. O estudo foi realizado no centro de referência em dermatologiasanitária dr. Marcelo cândia, em marituba, pará, brasil. Desses pacientes, 52% estavam na faixa etáriade 15 a 54 anos, 80,4% eram do sexo masculino, 80% tiveram alta por cura e 84% eram casos novos. A forma clínica predominante foi a dimorfa, com 68% dos casos. A forma virchowiana (mhv) apresentou maior número de pacientes com grau de incapacidade ii. A presença de incapacidade grau zero foi estatisticamente significante na forma dimorfa (mhd), que possui aproximadamente 2,69 vezes maior probabilidade de evoluir para neurite que a mhv. Os nervos periféricos mais afetados foram: o tibialposterior, o ulnar, o fibular e o mediano. Conclui-se que a forma virchowiana tem maior potencial de produção de incapacidades tipo ii, enquanto que os portadores de mhd evoluem mais vezes para neurite; e que não há diferença no acometimento de troncos nervosos em relação ao índice baciloscópico.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo2008-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3623710.47878/hi.2008.v33.36237Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 33 No. 2 (2008); 9-16Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 33 n. 2 (2008); 9-161982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/36237/34539https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCunha, Maria Heliana Chaves Monteiro daMacedo, Geraldo Mariano Moraes deBatista, Keila de Nazaré MadureiraXavier, Marilia BrasilNeto, Simone de SáNascimento, Francisca Souza do Nascimento e2023-02-17T18:21:54Zoai:ojs.periodicos.saude.sp.gov.br:article/36237Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-02-17T18:21:54Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon
Avaliação clínico-epidemiológica em pacientes multibacilares em uma unidade de referência de hansenologia da amazônia
title Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon
spellingShingle Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon
Cunha, Maria Heliana Chaves Monteiro da
hanseníase multibacilar
neurites clássicas
troncos nervosos afetados
grau de incapacidade
multibacillar leprosy
classic neuritis
affected nerve trunks
inability degree
title_short Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon
title_full Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon
title_fullStr Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon
title_full_unstemmed Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon
title_sort Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon
author Cunha, Maria Heliana Chaves Monteiro da
author_facet Cunha, Maria Heliana Chaves Monteiro da
Macedo, Geraldo Mariano Moraes de
Batista, Keila de Nazaré Madureira
Xavier, Marilia Brasil
Neto, Simone de Sá
Nascimento, Francisca Souza do Nascimento e
author_role author
author2 Macedo, Geraldo Mariano Moraes de
Batista, Keila de Nazaré Madureira
Xavier, Marilia Brasil
Neto, Simone de Sá
Nascimento, Francisca Souza do Nascimento e
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cunha, Maria Heliana Chaves Monteiro da
Macedo, Geraldo Mariano Moraes de
Batista, Keila de Nazaré Madureira
Xavier, Marilia Brasil
Neto, Simone de Sá
Nascimento, Francisca Souza do Nascimento e
dc.subject.por.fl_str_mv hanseníase multibacilar
neurites clássicas
troncos nervosos afetados
grau de incapacidade
multibacillar leprosy
classic neuritis
affected nerve trunks
inability degree
topic hanseníase multibacilar
neurites clássicas
troncos nervosos afetados
grau de incapacidade
multibacillar leprosy
classic neuritis
affected nerve trunks
inability degree
description Mycobacterium leprae (hansen’s baccillus) displays special immunogenic properties responsible by thehigh incapacitating power of leprae. The aims of this study were to determine the clinical-epidemic profileof multibacillar leprosum patients according to madri’s classification, correlate the baciloscopic index with the amount of nerve trunks affected by the classic neuritisprior and post-treatment, and correlate the inability degree of this patient with the clinical form at entrance and outcome. Medical records from 158 selected subjects with multibacilar leprosy from the center of reference in sanitary dermatology dr. Marcelo cândia, in marituba, pará, brazil were accessed to evaluate the baciloscopic and neurological exam. . Fifth two percent of the patients were in the range of 15 to 54 years, 80.4% Were male, 80% reach outcome for cure, and 84% were new cases. The predominant clinical form was dimorfa, comprising 68% of the cases. The virchowian form (mhv) was present in the majority of subjects with degree ii of incapacity, the presence of degree zero of incapacity was statistically significant in the dimorfa form (mhd), whose subjects displayed around 2.69 Fold more chance of evolving with neuritis symptoms than mhv. The most affected peripheric nerves at the moment and during the diagnosis were: tibia posterior, ulnar, fibula, and the to median nerve. In conclusion, mhv is at greater potential to develop degree ii of incapacity, whereas mhd barriers more frequently evolve to neuritis, and there is no difference among the nervous trunks affected in regard to the bacterious index.
publishDate 2008
dc.date.none.fl_str_mv 2008-11-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36237
10.47878/hi.2008.v33.36237
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/36237
identifier_str_mv 10.47878/hi.2008.v33.36237
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36237/34539
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 33 No. 2 (2008); 9-16
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 33 n. 2 (2008); 9-16
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
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