Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Hansenologia Internationalis (Online) |
Texto Completo: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/36237 |
Resumo: | Mycobacterium leprae (hansen’s baccillus) displays special immunogenic properties responsible by thehigh incapacitating power of leprae. The aims of this study were to determine the clinical-epidemic profileof multibacillar leprosum patients according to madri’s classification, correlate the baciloscopic index with the amount of nerve trunks affected by the classic neuritisprior and post-treatment, and correlate the inability degree of this patient with the clinical form at entrance and outcome. Medical records from 158 selected subjects with multibacilar leprosy from the center of reference in sanitary dermatology dr. Marcelo cândia, in marituba, pará, brazil were accessed to evaluate the baciloscopic and neurological exam. . Fifth two percent of the patients were in the range of 15 to 54 years, 80.4% Were male, 80% reach outcome for cure, and 84% were new cases. The predominant clinical form was dimorfa, comprising 68% of the cases. The virchowian form (mhv) was present in the majority of subjects with degree ii of incapacity, the presence of degree zero of incapacity was statistically significant in the dimorfa form (mhd), whose subjects displayed around 2.69 Fold more chance of evolving with neuritis symptoms than mhv. The most affected peripheric nerves at the moment and during the diagnosis were: tibia posterior, ulnar, fibula, and the to median nerve. In conclusion, mhv is at greater potential to develop degree ii of incapacity, whereas mhd barriers more frequently evolve to neuritis, and there is no difference among the nervous trunks affected in regard to the bacterious index. |
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Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazonAvaliação clínico-epidemiológica em pacientes multibacilares em uma unidade de referência de hansenologia da amazôniahanseníase multibacilarneurites clássicastroncos nervosos afetadosgrau de incapacidademultibacillar leprosyclassic neuritisaffected nerve trunksinability degreeMycobacterium leprae (hansen’s baccillus) displays special immunogenic properties responsible by thehigh incapacitating power of leprae. The aims of this study were to determine the clinical-epidemic profileof multibacillar leprosum patients according to madri’s classification, correlate the baciloscopic index with the amount of nerve trunks affected by the classic neuritisprior and post-treatment, and correlate the inability degree of this patient with the clinical form at entrance and outcome. Medical records from 158 selected subjects with multibacilar leprosy from the center of reference in sanitary dermatology dr. Marcelo cândia, in marituba, pará, brazil were accessed to evaluate the baciloscopic and neurological exam. . Fifth two percent of the patients were in the range of 15 to 54 years, 80.4% Were male, 80% reach outcome for cure, and 84% were new cases. The predominant clinical form was dimorfa, comprising 68% of the cases. The virchowian form (mhv) was present in the majority of subjects with degree ii of incapacity, the presence of degree zero of incapacity was statistically significant in the dimorfa form (mhd), whose subjects displayed around 2.69 Fold more chance of evolving with neuritis symptoms than mhv. The most affected peripheric nerves at the moment and during the diagnosis were: tibia posterior, ulnar, fibula, and the to median nerve. In conclusion, mhv is at greater potential to develop degree ii of incapacity, whereas mhd barriers more frequently evolve to neuritis, and there is no difference among the nervous trunks affected in regard to the bacterious index.O mycobacterium leprae (bacilo de hansen) possui propriedades imunogênicas especiais, responsáveis pelo alto poder incapacitante da hanseníase. Objetivou-se estudar o perfil clínico-epidemiológico de pacientes hansenianos multibacilares, de acordo com a classificação de madri, correlacionar o índice baciloscópico com o número de troncos afetados pela neurite franca no início e término do tratamento, correlacionar o grau de incapacidade com a forma clínica, à entrada e à saída desses pacientes. Selecionaram-se 158 prontuários de pacientes diagnosticados com hanseníase multibacilar, avaliados pelo exame baciloscópico e neurológico. O estudo foi realizado no centro de referência em dermatologiasanitária dr. Marcelo cândia, em marituba, pará, brasil. Desses pacientes, 52% estavam na faixa etáriade 15 a 54 anos, 80,4% eram do sexo masculino, 80% tiveram alta por cura e 84% eram casos novos. A forma clínica predominante foi a dimorfa, com 68% dos casos. A forma virchowiana (mhv) apresentou maior número de pacientes com grau de incapacidade ii. A presença de incapacidade grau zero foi estatisticamente significante na forma dimorfa (mhd), que possui aproximadamente 2,69 vezes maior probabilidade de evoluir para neurite que a mhv. Os nervos periféricos mais afetados foram: o tibialposterior, o ulnar, o fibular e o mediano. Conclui-se que a forma virchowiana tem maior potencial de produção de incapacidades tipo ii, enquanto que os portadores de mhd evoluem mais vezes para neurite; e que não há diferença no acometimento de troncos nervosos em relação ao índice baciloscópico.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo2008-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3623710.47878/hi.2008.v33.36237Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 33 No. 2 (2008); 9-16Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 33 n. 2 (2008); 9-161982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/36237/34539https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCunha, Maria Heliana Chaves Monteiro daMacedo, Geraldo Mariano Moraes deBatista, Keila de Nazaré MadureiraXavier, Marilia BrasilNeto, Simone de SáNascimento, Francisca Souza do Nascimento e2023-02-17T18:21:54Zoai:ojs.periodicos.saude.sp.gov.br:article/36237Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-02-17T18:21:54Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false |
dc.title.none.fl_str_mv |
Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon Avaliação clínico-epidemiológica em pacientes multibacilares em uma unidade de referência de hansenologia da amazônia |
title |
Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon |
spellingShingle |
Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon Cunha, Maria Heliana Chaves Monteiro da hanseníase multibacilar neurites clássicas troncos nervosos afetados grau de incapacidade multibacillar leprosy classic neuritis affected nerve trunks inability degree |
title_short |
Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon |
title_full |
Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon |
title_fullStr |
Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon |
title_full_unstemmed |
Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon |
title_sort |
Clinical and epidemiologycal evaluation of multibacillary patients from a reference center for leprosy in the brazilian amazon |
author |
Cunha, Maria Heliana Chaves Monteiro da |
author_facet |
Cunha, Maria Heliana Chaves Monteiro da Macedo, Geraldo Mariano Moraes de Batista, Keila de Nazaré Madureira Xavier, Marilia Brasil Neto, Simone de Sá Nascimento, Francisca Souza do Nascimento e |
author_role |
author |
author2 |
Macedo, Geraldo Mariano Moraes de Batista, Keila de Nazaré Madureira Xavier, Marilia Brasil Neto, Simone de Sá Nascimento, Francisca Souza do Nascimento e |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Cunha, Maria Heliana Chaves Monteiro da Macedo, Geraldo Mariano Moraes de Batista, Keila de Nazaré Madureira Xavier, Marilia Brasil Neto, Simone de Sá Nascimento, Francisca Souza do Nascimento e |
dc.subject.por.fl_str_mv |
hanseníase multibacilar neurites clássicas troncos nervosos afetados grau de incapacidade multibacillar leprosy classic neuritis affected nerve trunks inability degree |
topic |
hanseníase multibacilar neurites clássicas troncos nervosos afetados grau de incapacidade multibacillar leprosy classic neuritis affected nerve trunks inability degree |
description |
Mycobacterium leprae (hansen’s baccillus) displays special immunogenic properties responsible by thehigh incapacitating power of leprae. The aims of this study were to determine the clinical-epidemic profileof multibacillar leprosum patients according to madri’s classification, correlate the baciloscopic index with the amount of nerve trunks affected by the classic neuritisprior and post-treatment, and correlate the inability degree of this patient with the clinical form at entrance and outcome. Medical records from 158 selected subjects with multibacilar leprosy from the center of reference in sanitary dermatology dr. Marcelo cândia, in marituba, pará, brazil were accessed to evaluate the baciloscopic and neurological exam. . Fifth two percent of the patients were in the range of 15 to 54 years, 80.4% Were male, 80% reach outcome for cure, and 84% were new cases. The predominant clinical form was dimorfa, comprising 68% of the cases. The virchowian form (mhv) was present in the majority of subjects with degree ii of incapacity, the presence of degree zero of incapacity was statistically significant in the dimorfa form (mhd), whose subjects displayed around 2.69 Fold more chance of evolving with neuritis symptoms than mhv. The most affected peripheric nerves at the moment and during the diagnosis were: tibia posterior, ulnar, fibula, and the to median nerve. In conclusion, mhv is at greater potential to develop degree ii of incapacity, whereas mhd barriers more frequently evolve to neuritis, and there is no difference among the nervous trunks affected in regard to the bacterious index. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-11-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36237 10.47878/hi.2008.v33.36237 |
url |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36237 |
identifier_str_mv |
10.47878/hi.2008.v33.36237 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36237/34539 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
dc.source.none.fl_str_mv |
Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 33 No. 2 (2008); 9-16 Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 33 n. 2 (2008); 9-16 1982-5161 reponame:Hansenologia Internationalis (Online) instname:Instituto Lauro de Souza Lima (ILSL) instacron:ILSL |
instname_str |
Instituto Lauro de Souza Lima (ILSL) |
instacron_str |
ILSL |
institution |
ILSL |
reponame_str |
Hansenologia Internationalis (Online) |
collection |
Hansenologia Internationalis (Online) |
repository.name.fl_str_mv |
Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL) |
repository.mail.fl_str_mv |
hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br |
_version_ |
1796797580981567489 |