Reação de tipo pseudo-exacerbação e carcinoma bronquiolar dos pulmões
Autor(a) principal: | |
---|---|
Data de Publicação: | 1982 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Hansenologia Internationalis (Online) |
Texto Completo: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/36130 |
Resumo: | An elderly man with Hansen's disease during a period of twenty years and previously considered as an inactive Virchowian case, presented in the last four years of his life two episodes of reversal reaction (pseudo-exacerbation), the last one at the time of a hospital internation for severe respiratory symptoms. During this internation a diagnosis of bronchiolar carcinoma was made and seven months later the patient died due to progressive respiratory insufficiency. The paper discusses the problems involved in making a differential diagnosis between this particular form of carcinoma and other diseases with similar clinical and X-ray characteristics, as well as the difficulties involved in arriving at the diagnosis of bronchiolar carcinoma only by the means of an evaluation of a single lung biopsy. In relation to the reversal reaction episodes, two different interpretations are contrasted: one being the possibility that these reactions can result as consequences of bacillary growth which can occur in any phase of the infections course in borderline patients due to irregular treatment or drug resistance. The paper also analyses the possible relations between the last reactional episode and secondary immunological changes brought about by the lung tumor. |
id |
ILSL-1_730504d4bedc46e99319a6fd4913ea8a |
---|---|
oai_identifier_str |
oai:ojs.periodicos.saude.sp.gov.br:article/36130 |
network_acronym_str |
ILSL-1 |
network_name_str |
Hansenologia Internationalis (Online) |
repository_id_str |
|
spelling |
Reação de tipo pseudo-exacerbação e carcinoma bronquiolar dos pulmõesHanseníase dimorfaHanseníase virchowianaReação de pseudoexacerbaçãoCarcinoma bronquiolarPulmãoDimorphous hanseniasisVirchowian hanseniasisReversal reactionBronchiolar carcinomaLungAn elderly man with Hansen's disease during a period of twenty years and previously considered as an inactive Virchowian case, presented in the last four years of his life two episodes of reversal reaction (pseudo-exacerbation), the last one at the time of a hospital internation for severe respiratory symptoms. During this internation a diagnosis of bronchiolar carcinoma was made and seven months later the patient died due to progressive respiratory insufficiency. The paper discusses the problems involved in making a differential diagnosis between this particular form of carcinoma and other diseases with similar clinical and X-ray characteristics, as well as the difficulties involved in arriving at the diagnosis of bronchiolar carcinoma only by the means of an evaluation of a single lung biopsy. In relation to the reversal reaction episodes, two different interpretations are contrasted: one being the possibility that these reactions can result as consequences of bacillary growth which can occur in any phase of the infections course in borderline patients due to irregular treatment or drug resistance. The paper also analyses the possible relations between the last reactional episode and secondary immunological changes brought about by the lung tumor.Um paciente, portador de infecção hansênica há 20 anos, e considerado como virchowiano inativado, apresentou nos últimos 4 anos de vida, dois surtos de reação de pseudo-exacerbação (reação reversa), o último deles coincidindo com internação onde foi diagnosticado um carcinoma bronquiolar dos pulmões, cujo agravamento ocasionou o óbito. Discutem-se as dificuldades do diagnóstico clínico diferencial deste tipo de carcinoma pulmonar com outras patologias com características clínicas e evolutivas semelhantes, bem como a dificuldade de se chegar a este diagnóstico apenas pela análise de uma biopsia pulmonar. Em relação às reações de pseudo-exacerbação, duas interpretações são postas em confronto, e é salientada a hipótese destas reações se desenvolverem como resposta a surtos de proliferação bacilar que podem ocorrer em pacientes dimorfos em qualquer fase da evolução da infecção, devido a tratamento inadequado ou resistência medicamentosa. Também analisa-se a eventual relação do último surto reacional com alterações da imunidade celular secundárias ao desenvolvimento da neoplasia pulmonar.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1982-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3613010.47878/hi.1982.v7.36130Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 7 No. 2 (1982); 95-104Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 7 n. 2 (1982); 95-1041982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/36130/34441https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFLEURY, R. N.OLIVEIRA, Marlene deCÂMARA, Isabel C. P.URA, Somei2023-11-23T15:24:57Zoai:ojs.periodicos.saude.sp.gov.br:article/36130Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-11-23T15:24:57Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false |
dc.title.none.fl_str_mv |
Reação de tipo pseudo-exacerbação e carcinoma bronquiolar dos pulmões |
title |
Reação de tipo pseudo-exacerbação e carcinoma bronquiolar dos pulmões |
spellingShingle |
Reação de tipo pseudo-exacerbação e carcinoma bronquiolar dos pulmões FLEURY, R. N. Hanseníase dimorfa Hanseníase virchowiana Reação de pseudoexacerbação Carcinoma bronquiolar Pulmão Dimorphous hanseniasis Virchowian hanseniasis Reversal reaction Bronchiolar carcinoma Lung |
title_short |
Reação de tipo pseudo-exacerbação e carcinoma bronquiolar dos pulmões |
title_full |
Reação de tipo pseudo-exacerbação e carcinoma bronquiolar dos pulmões |
title_fullStr |
Reação de tipo pseudo-exacerbação e carcinoma bronquiolar dos pulmões |
title_full_unstemmed |
Reação de tipo pseudo-exacerbação e carcinoma bronquiolar dos pulmões |
title_sort |
Reação de tipo pseudo-exacerbação e carcinoma bronquiolar dos pulmões |
author |
FLEURY, R. N. |
author_facet |
FLEURY, R. N. OLIVEIRA, Marlene de CÂMARA, Isabel C. P. URA, Somei |
author_role |
author |
author2 |
OLIVEIRA, Marlene de CÂMARA, Isabel C. P. URA, Somei |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
FLEURY, R. N. OLIVEIRA, Marlene de CÂMARA, Isabel C. P. URA, Somei |
dc.subject.por.fl_str_mv |
Hanseníase dimorfa Hanseníase virchowiana Reação de pseudoexacerbação Carcinoma bronquiolar Pulmão Dimorphous hanseniasis Virchowian hanseniasis Reversal reaction Bronchiolar carcinoma Lung |
topic |
Hanseníase dimorfa Hanseníase virchowiana Reação de pseudoexacerbação Carcinoma bronquiolar Pulmão Dimorphous hanseniasis Virchowian hanseniasis Reversal reaction Bronchiolar carcinoma Lung |
description |
An elderly man with Hansen's disease during a period of twenty years and previously considered as an inactive Virchowian case, presented in the last four years of his life two episodes of reversal reaction (pseudo-exacerbation), the last one at the time of a hospital internation for severe respiratory symptoms. During this internation a diagnosis of bronchiolar carcinoma was made and seven months later the patient died due to progressive respiratory insufficiency. The paper discusses the problems involved in making a differential diagnosis between this particular form of carcinoma and other diseases with similar clinical and X-ray characteristics, as well as the difficulties involved in arriving at the diagnosis of bronchiolar carcinoma only by the means of an evaluation of a single lung biopsy. In relation to the reversal reaction episodes, two different interpretations are contrasted: one being the possibility that these reactions can result as consequences of bacillary growth which can occur in any phase of the infections course in borderline patients due to irregular treatment or drug resistance. The paper also analyses the possible relations between the last reactional episode and secondary immunological changes brought about by the lung tumor. |
publishDate |
1982 |
dc.date.none.fl_str_mv |
1982-11-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36130 10.47878/hi.1982.v7.36130 |
url |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36130 |
identifier_str_mv |
10.47878/hi.1982.v7.36130 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36130/34441 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
dc.source.none.fl_str_mv |
Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 7 No. 2 (1982); 95-104 Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 7 n. 2 (1982); 95-104 1982-5161 reponame:Hansenologia Internationalis (Online) instname:Instituto Lauro de Souza Lima (ILSL) instacron:ILSL |
instname_str |
Instituto Lauro de Souza Lima (ILSL) |
instacron_str |
ILSL |
institution |
ILSL |
reponame_str |
Hansenologia Internationalis (Online) |
collection |
Hansenologia Internationalis (Online) |
repository.name.fl_str_mv |
Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL) |
repository.mail.fl_str_mv |
hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br |
_version_ |
1796797580562137088 |