CLINICAL, EPIDEMIOLOGICAL AND IMMUNOLOGICAL STUDY TO AMERICAN TEGUMENTARY LEISHMANIASIS IN A DERMATOLOGY REFERENCE CENTER

• Autor(a) principal: Brito, Fernanda Freitas de
• Data de Publicação: 2015
• Outros Autores: Pinto, Ana Cecilia Versiane Duarte, Cavalcante, Maria Lopes Lamenha Lins, Silva, Gardênia Viana da, Wachholz, Patrick Alexander, Nascimento, Dejair Caitano do
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Hansenologia Internationalis (Online)
• Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35004
• topic: Leishmaniose; Epidemiologia; Diagnóstico; Imunofluorescencia indireta; Reação de Montenegro; Leishmaniasis; Epidemiology; Diagnosis; Fluorescent Antibody Technique; Montenegro skin test

Introduction: American cutaneous leishmaniasis (ACL) is an infectious disease caused by protozoa of the genus Leishmania. World leishmaniasis is an important endemic disease and public healthproblem in developing countries. Methods: We conducted a retrospective, descriptive and analytical cross-sectional study of 34 patients diagnosed with ACL. Statistical analysis was performed using the nonparametric Spearman’s test. Results: The gender involved was male (68%) and female (32%); the age range of 1 to 92 years old. The most common clinical manifestations were localized cutaneous form (79.5%) and the ulcers (56%).The face was main affected area (44%) and the minor time from onset of symptoms to consultation was 10 months (68%) of patients. Montenegro skin test (MST) was performed in 29 patients, being positive in (89.6%) and the indirect immunofluorescence (IIF) in only 16 patients, being positive in 13. The age and the duration of the disease were significantly associated with MST. Conclusions: It was not observed the IFI association with the patient’s age and disease duration. The treatment was in most cases, meglumine antimoniate (71%), followed Pentamidine (17%). The results demonstrated that the serological tests constitute an auxiliary tool and the correlations with clinical and histopathologicalfindings are essential.