Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Hansenologia Internationalis (Online) |
Texto Completo: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/36302 |
Resumo: | The treatment of leprosy is not limited to the cure of patient with leprosy bacilli, considering that the possible physical disabilities leprosy-induced are one of the most stigmatizing factors. With the changing of arrangement in the multi-drug therapy, from 24 to 12 doses, the need to get a better knowledge of how these patients have been behaving, when the drugs are out, regarding physical disabilities and (side effects reactions) outbreaks reaction. This is a cross-sectional study, to verify the degreesof physical disabilities in hands and feet, after high drug therapy from 1998 to 2000 being reevaluated in 2005. We evaluated 60 patients where 30 patients were treated with 12 doses and 30 patients were treated with 24 doses of three reference leprosy treatment centers in Plano Piloto - Brasilia. The presence of disabilities is related to the number of outbreaks reaction (side effects reactions).The Patients that were treated with 12 doses tended to produce more post-treatment reactions (10%), while those treated with 24 doses had a higher rate of reactions during treatment. Concerning the degrees of disability there was a significant worsening of the patients in both groups, in the second evaluation. There is a need for a greater control of post-discharge patients because the majority of further damage from leprosy reactions occurs when the drug therapy is out where the disabilities can appear. It is suggested that the patients’ monitoring becomes monthly to evaluate the development of reaction episodes and to prevent the development of the same degree of disability. |
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Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DFEstudo comparativo do índice de incapacidades em pacientes tratados com 24 e 12 doses de poliquimioterapia padrão – OMS, pacientes atendidos no plano piloto de Brasília – DFhanseníaseincapacidades físicaspoliquimioterapialeprosyphysical disabilitiesmulti-drug treatmentThe treatment of leprosy is not limited to the cure of patient with leprosy bacilli, considering that the possible physical disabilities leprosy-induced are one of the most stigmatizing factors. With the changing of arrangement in the multi-drug therapy, from 24 to 12 doses, the need to get a better knowledge of how these patients have been behaving, when the drugs are out, regarding physical disabilities and (side effects reactions) outbreaks reaction. This is a cross-sectional study, to verify the degreesof physical disabilities in hands and feet, after high drug therapy from 1998 to 2000 being reevaluated in 2005. We evaluated 60 patients where 30 patients were treated with 12 doses and 30 patients were treated with 24 doses of three reference leprosy treatment centers in Plano Piloto - Brasilia. The presence of disabilities is related to the number of outbreaks reaction (side effects reactions).The Patients that were treated with 12 doses tended to produce more post-treatment reactions (10%), while those treated with 24 doses had a higher rate of reactions during treatment. Concerning the degrees of disability there was a significant worsening of the patients in both groups, in the second evaluation. There is a need for a greater control of post-discharge patients because the majority of further damage from leprosy reactions occurs when the drug therapy is out where the disabilities can appear. It is suggested that the patients’ monitoring becomes monthly to evaluate the development of reaction episodes and to prevent the development of the same degree of disability.O tratamento da hanseníase não se limita apenas à cura bacilífera do doente, considerando que as incapacidades físicas que a doença pode gerar são um dos fatores mais estigmatizantes. Com a mudança do esquema terapêutico de poliquimioterapia de 24 para 12 doses, surgiu a necessidade de conhecer melhor como esses pacientes vêm se comportando, após a alta medicamentosa, em relação a incapacidades físicas e surtos reacionais. Trata-se de um estudo transversal, objetivando verificar graus de incapacidades físicas em mãos e pés, após alta terapêutica nos anos de 1998 a 2000 sendo reavaliados no ano de 2005. Foram avaliados 60 pacientes onde 30 pacientes tratados com 12 doses e 30 pacientes tratados com 24 doses de três centros de referência no tratamento da Hanseníase, no plano piloto de Brasília. A presença de incapacidades físicas está relacionada à quantidade de surtos reacionais. Os pacientes tratados com 12 doses tiveram tendência maior a apresentar reações pós-tratamento (10%), enquanto os tratados com 24 doses apresentaram um índice maior de reações durante o tratamento. Quanto ao grau de incapacidade, foi significativa a piora dos pacientes dos dois grupos, na segunda avaliação. Existe a necessidade de um controle maior deste pacientes pós-alta, pois a maioria das reações ocorre após a alta terapêutica onde podem surgir as incapacidades. Sugere-se que o acompanhamento dos pacientes seja mensalmente para avaliar as evoluções dos episódios reacionais e impedir evolução do grau de incapacidade dos mesmos.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo2007-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3630210.47878/hi.2007.v32.36302Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 32 No. 2 (2007); 163-174Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 32 n. 2 (2007); 163-1741982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/36302/34589https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessEscarabel, Claudia MariaAlvarez, Rosicler Rocha AizaCarvalho, Gustavo AzevedoMoreira, Demóstenes2023-02-17T18:43:11Zoai:ojs.periodicos.saude.sp.gov.br:article/36302Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-02-17T18:43:11Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false |
dc.title.none.fl_str_mv |
Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF Estudo comparativo do índice de incapacidades em pacientes tratados com 24 e 12 doses de poliquimioterapia padrão – OMS, pacientes atendidos no plano piloto de Brasília – DF |
title |
Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF |
spellingShingle |
Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF Escarabel, Claudia Maria hanseníase incapacidades físicas poliquimioterapia leprosy physical disabilities multi-drug treatment |
title_short |
Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF |
title_full |
Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF |
title_fullStr |
Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF |
title_full_unstemmed |
Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF |
title_sort |
Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF |
author |
Escarabel, Claudia Maria |
author_facet |
Escarabel, Claudia Maria Alvarez, Rosicler Rocha Aiza Carvalho, Gustavo Azevedo Moreira, Demóstenes |
author_role |
author |
author2 |
Alvarez, Rosicler Rocha Aiza Carvalho, Gustavo Azevedo Moreira, Demóstenes |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Escarabel, Claudia Maria Alvarez, Rosicler Rocha Aiza Carvalho, Gustavo Azevedo Moreira, Demóstenes |
dc.subject.por.fl_str_mv |
hanseníase incapacidades físicas poliquimioterapia leprosy physical disabilities multi-drug treatment |
topic |
hanseníase incapacidades físicas poliquimioterapia leprosy physical disabilities multi-drug treatment |
description |
The treatment of leprosy is not limited to the cure of patient with leprosy bacilli, considering that the possible physical disabilities leprosy-induced are one of the most stigmatizing factors. With the changing of arrangement in the multi-drug therapy, from 24 to 12 doses, the need to get a better knowledge of how these patients have been behaving, when the drugs are out, regarding physical disabilities and (side effects reactions) outbreaks reaction. This is a cross-sectional study, to verify the degreesof physical disabilities in hands and feet, after high drug therapy from 1998 to 2000 being reevaluated in 2005. We evaluated 60 patients where 30 patients were treated with 12 doses and 30 patients were treated with 24 doses of three reference leprosy treatment centers in Plano Piloto - Brasilia. The presence of disabilities is related to the number of outbreaks reaction (side effects reactions).The Patients that were treated with 12 doses tended to produce more post-treatment reactions (10%), while those treated with 24 doses had a higher rate of reactions during treatment. Concerning the degrees of disability there was a significant worsening of the patients in both groups, in the second evaluation. There is a need for a greater control of post-discharge patients because the majority of further damage from leprosy reactions occurs when the drug therapy is out where the disabilities can appear. It is suggested that the patients’ monitoring becomes monthly to evaluate the development of reaction episodes and to prevent the development of the same degree of disability. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-11-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36302 10.47878/hi.2007.v32.36302 |
url |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36302 |
identifier_str_mv |
10.47878/hi.2007.v32.36302 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/36302/34589 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
dc.source.none.fl_str_mv |
Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 32 No. 2 (2007); 163-174 Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 32 n. 2 (2007); 163-174 1982-5161 reponame:Hansenologia Internationalis (Online) instname:Instituto Lauro de Souza Lima (ILSL) instacron:ILSL |
instname_str |
Instituto Lauro de Souza Lima (ILSL) |
instacron_str |
ILSL |
institution |
ILSL |
reponame_str |
Hansenologia Internationalis (Online) |
collection |
Hansenologia Internationalis (Online) |
repository.name.fl_str_mv |
Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL) |
repository.mail.fl_str_mv |
hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br |
_version_ |
1796797581018267648 |