Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF

Detalhes bibliográficos
Autor(a) principal: Escarabel, Claudia Maria
Data de Publicação: 2007
Outros Autores: Alvarez, Rosicler Rocha Aiza, Carvalho, Gustavo Azevedo, Moreira, Demóstenes
Tipo de documento: Artigo
Idioma: por
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/36302
Resumo: The treatment of leprosy is not limited to the cure of patient with leprosy bacilli, considering that the possible physical disabilities leprosy-induced are one of the most stigmatizing factors. With the changing of arrangement in the multi-drug therapy, from 24 to 12 doses, the need to get a better knowledge of how these patients have been behaving, when the drugs are out, regarding physical disabilities and (side effects reactions) outbreaks reaction. This is a cross-sectional study, to verify the degreesof physical disabilities in hands and feet, after high drug therapy from 1998 to 2000 being reevaluated in 2005. We evaluated 60 patients where 30 patients were treated with 12 doses and 30 patients were treated with 24 doses of three reference leprosy treatment centers in Plano Piloto - Brasilia. The presence of disabilities is related to the number of outbreaks reaction (side effects reactions).The Patients that were treated with 12 doses tended to produce more post-treatment reactions (10%), while those treated with 24 doses had a higher rate of reactions during treatment. Concerning the degrees of disability there was a significant worsening of the patients in both groups, in the second evaluation. There is a need for a greater control of post-discharge patients because the majority of further damage from leprosy reactions occurs when the drug therapy is out where the disabilities can appear. It is suggested that the patients’ monitoring becomes monthly to evaluate the development of reaction episodes and to prevent the development of the same degree of disability.
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spelling Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DFEstudo comparativo do índice de incapacidades em pacientes tratados com 24 e 12 doses de poliquimioterapia padrão – OMS, pacientes atendidos no plano piloto de Brasília – DFhanseníaseincapacidades físicaspoliquimioterapialeprosyphysical disabilitiesmulti-drug treatmentThe treatment of leprosy is not limited to the cure of patient with leprosy bacilli, considering that the possible physical disabilities leprosy-induced are one of the most stigmatizing factors. With the changing of arrangement in the multi-drug therapy, from 24 to 12 doses, the need to get a better knowledge of how these patients have been behaving, when the drugs are out, regarding physical disabilities and (side effects reactions) outbreaks reaction. This is a cross-sectional study, to verify the degreesof physical disabilities in hands and feet, after high drug therapy from 1998 to 2000 being reevaluated in 2005. We evaluated 60 patients where 30 patients were treated with 12 doses and 30 patients were treated with 24 doses of three reference leprosy treatment centers in Plano Piloto - Brasilia. The presence of disabilities is related to the number of outbreaks reaction (side effects reactions).The Patients that were treated with 12 doses tended to produce more post-treatment reactions (10%), while those treated with 24 doses had a higher rate of reactions during treatment. Concerning the degrees of disability there was a significant worsening of the patients in both groups, in the second evaluation. There is a need for a greater control of post-discharge patients because the majority of further damage from leprosy reactions occurs when the drug therapy is out where the disabilities can appear. It is suggested that the patients’ monitoring becomes monthly to evaluate the development of reaction episodes and to prevent the development of the same degree of disability.O tratamento da hanseníase não se limita apenas à cura bacilífera do doente, considerando que as incapacidades físicas que a doença pode gerar são um dos fatores mais estigmatizantes. Com a mudança do esquema terapêutico de poliquimioterapia de 24 para 12 doses, surgiu a necessidade de conhecer melhor como esses pacientes vêm se comportando, após a alta medicamentosa, em relação a incapacidades físicas e surtos reacionais. Trata-se de um estudo transversal, objetivando verificar graus de incapacidades físicas em mãos e pés, após alta terapêutica nos anos de 1998 a 2000 sendo reavaliados no ano de 2005. Foram avaliados 60 pacientes onde 30 pacientes tratados com 12 doses e 30 pacientes tratados com 24 doses de três centros de referência no tratamento da Hanseníase, no plano piloto de Brasília. A presença de incapacidades físicas está relacionada à quantidade de surtos reacionais. Os pacientes tratados com 12 doses tiveram tendência maior a apresentar reações pós-tratamento (10%), enquanto os tratados com 24 doses apresentaram um índice maior de reações durante o tratamento. Quanto ao grau de incapacidade, foi significativa a piora dos pacientes dos dois grupos, na segunda avaliação. Existe a necessidade de um controle maior deste pacientes pós-alta, pois a maioria das reações ocorre após a alta terapêutica onde podem surgir as incapacidades. Sugere-se que o acompanhamento dos pacientes seja mensalmente para avaliar as evoluções dos episódios reacionais e impedir evolução do grau de incapacidade dos mesmos.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo2007-11-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3630210.47878/hi.2007.v32.36302Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 32 No. 2 (2007); 163-174Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 32 n. 2 (2007); 163-1741982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLporhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/36302/34589https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessEscarabel, Claudia MariaAlvarez, Rosicler Rocha AizaCarvalho, Gustavo AzevedoMoreira, Demóstenes2023-02-17T18:43:11Zoai:ojs.periodicos.saude.sp.gov.br:article/36302Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2023-02-17T18:43:11Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF
Estudo comparativo do índice de incapacidades em pacientes tratados com 24 e 12 doses de poliquimioterapia padrão – OMS, pacientes atendidos no plano piloto de Brasília – DF
title Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF
spellingShingle Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF
Escarabel, Claudia Maria
hanseníase
incapacidades físicas
poliquimioterapia
leprosy
physical disabilities
multi-drug treatment
title_short Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF
title_full Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF
title_fullStr Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF
title_full_unstemmed Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF
title_sort Compartive study of the disability grade in treated patients with 12 and 24 doses of multidrugtherapy/WHO – patients attended in Brasília - DF
author Escarabel, Claudia Maria
author_facet Escarabel, Claudia Maria
Alvarez, Rosicler Rocha Aiza
Carvalho, Gustavo Azevedo
Moreira, Demóstenes
author_role author
author2 Alvarez, Rosicler Rocha Aiza
Carvalho, Gustavo Azevedo
Moreira, Demóstenes
author2_role author
author
author
dc.contributor.author.fl_str_mv Escarabel, Claudia Maria
Alvarez, Rosicler Rocha Aiza
Carvalho, Gustavo Azevedo
Moreira, Demóstenes
dc.subject.por.fl_str_mv hanseníase
incapacidades físicas
poliquimioterapia
leprosy
physical disabilities
multi-drug treatment
topic hanseníase
incapacidades físicas
poliquimioterapia
leprosy
physical disabilities
multi-drug treatment
description The treatment of leprosy is not limited to the cure of patient with leprosy bacilli, considering that the possible physical disabilities leprosy-induced are one of the most stigmatizing factors. With the changing of arrangement in the multi-drug therapy, from 24 to 12 doses, the need to get a better knowledge of how these patients have been behaving, when the drugs are out, regarding physical disabilities and (side effects reactions) outbreaks reaction. This is a cross-sectional study, to verify the degreesof physical disabilities in hands and feet, after high drug therapy from 1998 to 2000 being reevaluated in 2005. We evaluated 60 patients where 30 patients were treated with 12 doses and 30 patients were treated with 24 doses of three reference leprosy treatment centers in Plano Piloto - Brasilia. The presence of disabilities is related to the number of outbreaks reaction (side effects reactions).The Patients that were treated with 12 doses tended to produce more post-treatment reactions (10%), while those treated with 24 doses had a higher rate of reactions during treatment. Concerning the degrees of disability there was a significant worsening of the patients in both groups, in the second evaluation. There is a need for a greater control of post-discharge patients because the majority of further damage from leprosy reactions occurs when the drug therapy is out where the disabilities can appear. It is suggested that the patients’ monitoring becomes monthly to evaluate the development of reaction episodes and to prevent the development of the same degree of disability.
publishDate 2007
dc.date.none.fl_str_mv 2007-11-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36302
10.47878/hi.2007.v32.36302
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/36302
identifier_str_mv 10.47878/hi.2007.v32.36302
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/36302/34589
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 32 No. 2 (2007); 163-174
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 32 n. 2 (2007); 163-174
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
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