COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Saúde Materno Infantil (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292021000100299 |
Resumo: | Abstract Objectives: to describe epidemiological characteristics and deaths in children with cancer and COVID-19 at a reference hospital in Recife, Brazil. Methods: cohort involving children under the age of 19 underwent cancer treatment during April to July 2020. During the pandemic, real-time reverse transcriptase polymerase chain reaction assay (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS -CoV-2) in nasal / oropharyngeal swab were collected in symptomatic patients or before hospitalization. Those with detectable results were included in this cohort study. The outcomes were delayed on cancer treatment and death. Descriptive analysis was performed and presented in preliminary results. Results: 48 children participated in the cohort, mostly with hematological neoplasms (66.6%.),69% were male, median age was 5.5 years. The most frequent symptoms were fever (58.3%) and coughing (27.7%);72.9% required hospitalization, 20% had support in ICU and 10.5% on invasive ventilatory assistance.66.6% of the patients had their oncological treatment postponed, 16.6% died within 60 days after confirmation of SARS-CoV-2 infection. Conclusions: COVID-19 led a delay in the oncological treatment for children with cancer and a higher mortality frequency when compared to the historical series of the service. It would be important to analyze the risk factors to determine the survival impact. |
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Revista Brasileira de Saúde Materno Infantil (Online) |
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COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deathsCOVID-19ChildMortalityNeoplasmsCoronavirus infectionsAbstract Objectives: to describe epidemiological characteristics and deaths in children with cancer and COVID-19 at a reference hospital in Recife, Brazil. Methods: cohort involving children under the age of 19 underwent cancer treatment during April to July 2020. During the pandemic, real-time reverse transcriptase polymerase chain reaction assay (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS -CoV-2) in nasal / oropharyngeal swab were collected in symptomatic patients or before hospitalization. Those with detectable results were included in this cohort study. The outcomes were delayed on cancer treatment and death. Descriptive analysis was performed and presented in preliminary results. Results: 48 children participated in the cohort, mostly with hematological neoplasms (66.6%.),69% were male, median age was 5.5 years. The most frequent symptoms were fever (58.3%) and coughing (27.7%);72.9% required hospitalization, 20% had support in ICU and 10.5% on invasive ventilatory assistance.66.6% of the patients had their oncological treatment postponed, 16.6% died within 60 days after confirmation of SARS-CoV-2 infection. Conclusions: COVID-19 led a delay in the oncological treatment for children with cancer and a higher mortality frequency when compared to the historical series of the service. It would be important to analyze the risk factors to determine the survival impact.Instituto de Medicina Integral Prof. Fernando Figueira2021-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292021000100299Revista Brasileira de Saúde Materno Infantil v.21 suppl.1 2021reponame:Revista Brasileira de Saúde Materno Infantil (Online)instname:Instituto de Medicina Integral Prof. Fernando Figueira (IMIPFF)instacron:IMIPFF10.1590/1806-9304202100s100017info:eu-repo/semantics/openAccessLima,Ana Luiza Magalhães de AndradeBorborema,Maria do Céu DinizMatos,Ana Paula RodriguesOliveira,Kaline Maria Maciel deMello,Maria Júlia GonçalvesLins,Mecneide Mendeseng2021-02-19T00:00:00Zoai:scielo:S1519-38292021000100299Revistahttp://www.scielo.br/rbsmihttps://old.scielo.br/oai/scielo-oai.php||revista@imip.org.br1806-93041519-3829opendoar:2021-02-19T00:00Revista Brasileira de Saúde Materno Infantil (Online) - Instituto de Medicina Integral Prof. Fernando Figueira (IMIPFF)false |
dc.title.none.fl_str_mv |
COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths |
title |
COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths |
spellingShingle |
COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths Lima,Ana Luiza Magalhães de Andrade COVID-19 Child Mortality Neoplasms Coronavirus infections |
title_short |
COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths |
title_full |
COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths |
title_fullStr |
COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths |
title_full_unstemmed |
COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths |
title_sort |
COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths |
author |
Lima,Ana Luiza Magalhães de Andrade |
author_facet |
Lima,Ana Luiza Magalhães de Andrade Borborema,Maria do Céu Diniz Matos,Ana Paula Rodrigues Oliveira,Kaline Maria Maciel de Mello,Maria Júlia Gonçalves Lins,Mecneide Mendes |
author_role |
author |
author2 |
Borborema,Maria do Céu Diniz Matos,Ana Paula Rodrigues Oliveira,Kaline Maria Maciel de Mello,Maria Júlia Gonçalves Lins,Mecneide Mendes |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Lima,Ana Luiza Magalhães de Andrade Borborema,Maria do Céu Diniz Matos,Ana Paula Rodrigues Oliveira,Kaline Maria Maciel de Mello,Maria Júlia Gonçalves Lins,Mecneide Mendes |
dc.subject.por.fl_str_mv |
COVID-19 Child Mortality Neoplasms Coronavirus infections |
topic |
COVID-19 Child Mortality Neoplasms Coronavirus infections |
description |
Abstract Objectives: to describe epidemiological characteristics and deaths in children with cancer and COVID-19 at a reference hospital in Recife, Brazil. Methods: cohort involving children under the age of 19 underwent cancer treatment during April to July 2020. During the pandemic, real-time reverse transcriptase polymerase chain reaction assay (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS -CoV-2) in nasal / oropharyngeal swab were collected in symptomatic patients or before hospitalization. Those with detectable results were included in this cohort study. The outcomes were delayed on cancer treatment and death. Descriptive analysis was performed and presented in preliminary results. Results: 48 children participated in the cohort, mostly with hematological neoplasms (66.6%.),69% were male, median age was 5.5 years. The most frequent symptoms were fever (58.3%) and coughing (27.7%);72.9% required hospitalization, 20% had support in ICU and 10.5% on invasive ventilatory assistance.66.6% of the patients had their oncological treatment postponed, 16.6% died within 60 days after confirmation of SARS-CoV-2 infection. Conclusions: COVID-19 led a delay in the oncological treatment for children with cancer and a higher mortality frequency when compared to the historical series of the service. It would be important to analyze the risk factors to determine the survival impact. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292021000100299 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292021000100299 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1806-9304202100s100017 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Medicina Integral Prof. Fernando Figueira |
publisher.none.fl_str_mv |
Instituto de Medicina Integral Prof. Fernando Figueira |
dc.source.none.fl_str_mv |
Revista Brasileira de Saúde Materno Infantil v.21 suppl.1 2021 reponame:Revista Brasileira de Saúde Materno Infantil (Online) instname:Instituto de Medicina Integral Prof. Fernando Figueira (IMIPFF) instacron:IMIPFF |
instname_str |
Instituto de Medicina Integral Prof. Fernando Figueira (IMIPFF) |
instacron_str |
IMIPFF |
institution |
IMIPFF |
reponame_str |
Revista Brasileira de Saúde Materno Infantil (Online) |
collection |
Revista Brasileira de Saúde Materno Infantil (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Saúde Materno Infantil (Online) - Instituto de Medicina Integral Prof. Fernando Figueira (IMIPFF) |
repository.mail.fl_str_mv |
||revista@imip.org.br |
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1752129930698686464 |