COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths

Detalhes bibliográficos
Autor(a) principal: Lima,Ana Luiza Magalhães de Andrade
Data de Publicação: 2021
Outros Autores: Borborema,Maria do Céu Diniz, Matos,Ana Paula Rodrigues, Oliveira,Kaline Maria Maciel de, Mello,Maria Júlia Gonçalves, Lins,Mecneide Mendes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Saúde Materno Infantil (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292021000100299
Resumo: Abstract Objectives: to describe epidemiological characteristics and deaths in children with cancer and COVID-19 at a reference hospital in Recife, Brazil. Methods: cohort involving children under the age of 19 underwent cancer treatment during April to July 2020. During the pandemic, real-time reverse transcriptase polymerase chain reaction assay (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS -CoV-2) in nasal / oropharyngeal swab were collected in symptomatic patients or before hospitalization. Those with detectable results were included in this cohort study. The outcomes were delayed on cancer treatment and death. Descriptive analysis was performed and presented in preliminary results. Results: 48 children participated in the cohort, mostly with hematological neoplasms (66.6%.),69% were male, median age was 5.5 years. The most frequent symptoms were fever (58.3%) and coughing (27.7%);72.9% required hospitalization, 20% had support in ICU and 10.5% on invasive ventilatory assistance.66.6% of the patients had their oncological treatment postponed, 16.6% died within 60 days after confirmation of SARS-CoV-2 infection. Conclusions: COVID-19 led a delay in the oncological treatment for children with cancer and a higher mortality frequency when compared to the historical series of the service. It would be important to analyze the risk factors to determine the survival impact.
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spelling COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deathsCOVID-19ChildMortalityNeoplasmsCoronavirus infectionsAbstract Objectives: to describe epidemiological characteristics and deaths in children with cancer and COVID-19 at a reference hospital in Recife, Brazil. Methods: cohort involving children under the age of 19 underwent cancer treatment during April to July 2020. During the pandemic, real-time reverse transcriptase polymerase chain reaction assay (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS -CoV-2) in nasal / oropharyngeal swab were collected in symptomatic patients or before hospitalization. Those with detectable results were included in this cohort study. The outcomes were delayed on cancer treatment and death. Descriptive analysis was performed and presented in preliminary results. Results: 48 children participated in the cohort, mostly with hematological neoplasms (66.6%.),69% were male, median age was 5.5 years. The most frequent symptoms were fever (58.3%) and coughing (27.7%);72.9% required hospitalization, 20% had support in ICU and 10.5% on invasive ventilatory assistance.66.6% of the patients had their oncological treatment postponed, 16.6% died within 60 days after confirmation of SARS-CoV-2 infection. Conclusions: COVID-19 led a delay in the oncological treatment for children with cancer and a higher mortality frequency when compared to the historical series of the service. It would be important to analyze the risk factors to determine the survival impact.Instituto de Medicina Integral Prof. Fernando Figueira2021-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292021000100299Revista Brasileira de Saúde Materno Infantil v.21 suppl.1 2021reponame:Revista Brasileira de Saúde Materno Infantil (Online)instname:Instituto de Medicina Integral Prof. Fernando Figueira (IMIPFF)instacron:IMIPFF10.1590/1806-9304202100s100017info:eu-repo/semantics/openAccessLima,Ana Luiza Magalhães de AndradeBorborema,Maria do Céu DinizMatos,Ana Paula RodriguesOliveira,Kaline Maria Maciel deMello,Maria Júlia GonçalvesLins,Mecneide Mendeseng2021-02-19T00:00:00Zoai:scielo:S1519-38292021000100299Revistahttp://www.scielo.br/rbsmihttps://old.scielo.br/oai/scielo-oai.php||revista@imip.org.br1806-93041519-3829opendoar:2021-02-19T00:00Revista Brasileira de Saúde Materno Infantil (Online) - Instituto de Medicina Integral Prof. Fernando Figueira (IMIPFF)false
dc.title.none.fl_str_mv COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths
title COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths
spellingShingle COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths
Lima,Ana Luiza Magalhães de Andrade
COVID-19
Child
Mortality
Neoplasms
Coronavirus infections
title_short COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths
title_full COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths
title_fullStr COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths
title_full_unstemmed COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths
title_sort COVID-19 cohort on children with cancer: delay in treatment and increased frequency of deaths
author Lima,Ana Luiza Magalhães de Andrade
author_facet Lima,Ana Luiza Magalhães de Andrade
Borborema,Maria do Céu Diniz
Matos,Ana Paula Rodrigues
Oliveira,Kaline Maria Maciel de
Mello,Maria Júlia Gonçalves
Lins,Mecneide Mendes
author_role author
author2 Borborema,Maria do Céu Diniz
Matos,Ana Paula Rodrigues
Oliveira,Kaline Maria Maciel de
Mello,Maria Júlia Gonçalves
Lins,Mecneide Mendes
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Lima,Ana Luiza Magalhães de Andrade
Borborema,Maria do Céu Diniz
Matos,Ana Paula Rodrigues
Oliveira,Kaline Maria Maciel de
Mello,Maria Júlia Gonçalves
Lins,Mecneide Mendes
dc.subject.por.fl_str_mv COVID-19
Child
Mortality
Neoplasms
Coronavirus infections
topic COVID-19
Child
Mortality
Neoplasms
Coronavirus infections
description Abstract Objectives: to describe epidemiological characteristics and deaths in children with cancer and COVID-19 at a reference hospital in Recife, Brazil. Methods: cohort involving children under the age of 19 underwent cancer treatment during April to July 2020. During the pandemic, real-time reverse transcriptase polymerase chain reaction assay (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS -CoV-2) in nasal / oropharyngeal swab were collected in symptomatic patients or before hospitalization. Those with detectable results were included in this cohort study. The outcomes were delayed on cancer treatment and death. Descriptive analysis was performed and presented in preliminary results. Results: 48 children participated in the cohort, mostly with hematological neoplasms (66.6%.),69% were male, median age was 5.5 years. The most frequent symptoms were fever (58.3%) and coughing (27.7%);72.9% required hospitalization, 20% had support in ICU and 10.5% on invasive ventilatory assistance.66.6% of the patients had their oncological treatment postponed, 16.6% died within 60 days after confirmation of SARS-CoV-2 infection. Conclusions: COVID-19 led a delay in the oncological treatment for children with cancer and a higher mortality frequency when compared to the historical series of the service. It would be important to analyze the risk factors to determine the survival impact.
publishDate 2021
dc.date.none.fl_str_mv 2021-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292021000100299
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-38292021000100299
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1806-9304202100s100017
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto de Medicina Integral Prof. Fernando Figueira
publisher.none.fl_str_mv Instituto de Medicina Integral Prof. Fernando Figueira
dc.source.none.fl_str_mv Revista Brasileira de Saúde Materno Infantil v.21 suppl.1 2021
reponame:Revista Brasileira de Saúde Materno Infantil (Online)
instname:Instituto de Medicina Integral Prof. Fernando Figueira (IMIPFF)
instacron:IMIPFF
instname_str Instituto de Medicina Integral Prof. Fernando Figueira (IMIPFF)
instacron_str IMIPFF
institution IMIPFF
reponame_str Revista Brasileira de Saúde Materno Infantil (Online)
collection Revista Brasileira de Saúde Materno Infantil (Online)
repository.name.fl_str_mv Revista Brasileira de Saúde Materno Infantil (Online) - Instituto de Medicina Integral Prof. Fernando Figueira (IMIPFF)
repository.mail.fl_str_mv ||revista@imip.org.br
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