Nephrotic syndrome associated with hepatointestinal schistosomiasis

• Autor(a) principal: Abensur, H.
• Data de Publicação: 1992
• Outros Autores: Nussenzveig, I., Saldanha, L.B., Petalozzi, M.S.C., Barros, M.T., Marcondes, M., Barros, R.T.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
• Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/28933
• topic: Schistosoma mansoni; Schistosomal associated nephropathy; Nephrotic syndrome; Hepatointestinal schistosomiasis

Schistosomal nephropathy has long been related to the hepatosplenic form of schistosomiasis. In the last few years, 24 patients with hepatointestinal schistosomiasis and the nephrotic syndrome were studied. Aiming at evaluating a possible etiologic participation of schistosomiasis in the development of the nephropathy, this group was comparatively studied with a group of 37 patients with idiopathic nephrotic syndrome. Both groups had a different distribution of the histologic lesions. In the group with schistosomiasis there was a statistically significant prevalence of proliferative mesangial glomerulonephritis (33.3%), whereas in the control group there was prevalence of membranous glomerulonephritis (32.4%). On immunofluorescence, IgM was positive in 94.4% of the patients with schistosomiasis versus 55.0% in the control group (p