Orbital tuberculosis diagnosed by immunohistochemistry: case reports
Autor(a) principal: | |
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Data de Publicação: | 2004 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/30847 |
Resumo: | PURPOSE: To describe three cases of orbital tuberculosis, with their clinical characteristics and respective diagnostic procedures, showing the importance of histopathology for the correct diagnosis. PATIENTS AND METHODS: Three patients diagnosed and treated for orbital tuberculosis, in the "Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo" during the years of 1999 and 2001. RESULTS: All of the patients were female and referred a chronic evolution of swelling of one eyelid associated or not with other symptoms. They had not HIV infection. Two of them had positive epidemiology for tuberculosis. However, the search for systemic evidence of the disease and staining for bacilli (Ziehl-Neelsen method) were negative in all three patients. In all the cases, only the biopsy with immunohistochemical analysis could confirm the diagnosis. COMMENTS: Orbital involvement is a rare ocular manifestation of tuberculosis. Even in a tertiary hospital, few cases, if any, are diagnosed per year. However, the global incidence and prevalence of M. tuberculosis infections is not under control yet, and it has been a serious public health problem. Thus, one must be aware of the possibility of tuberculosis among the orbital diseases. |
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Orbital tuberculosis diagnosed by immunohistochemistry: case reports Tuberculose orbitária diagnosticada por imunohistoquímica TuberculosisOrbitDiagnosisImmunochemistry PURPOSE: To describe three cases of orbital tuberculosis, with their clinical characteristics and respective diagnostic procedures, showing the importance of histopathology for the correct diagnosis. PATIENTS AND METHODS: Three patients diagnosed and treated for orbital tuberculosis, in the "Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo" during the years of 1999 and 2001. RESULTS: All of the patients were female and referred a chronic evolution of swelling of one eyelid associated or not with other symptoms. They had not HIV infection. Two of them had positive epidemiology for tuberculosis. However, the search for systemic evidence of the disease and staining for bacilli (Ziehl-Neelsen method) were negative in all three patients. In all the cases, only the biopsy with immunohistochemical analysis could confirm the diagnosis. COMMENTS: Orbital involvement is a rare ocular manifestation of tuberculosis. Even in a tertiary hospital, few cases, if any, are diagnosed per year. However, the global incidence and prevalence of M. tuberculosis infections is not under control yet, and it has been a serious public health problem. Thus, one must be aware of the possibility of tuberculosis among the orbital diseases. OBJETIVO: Este estudo descreve 3 casos de tuberculose orbitária, com suas características clínicas, procedimentos diagnósticos, mostrando a importância da histopatologia para o diagnóstico correto. PACIENTES E MÉTODOS: Descrição de 3 casos de pacientes com tuberculose orbitária diagnosticada e tratada no Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo entre os anos 1999 e 2001 RESULTADOS: Todos os casos apresentaram-se como massa orbitária de evolução lenta e progressiva em pacientes de sexo feminino, sem doença pulmonar concomitante evidente. Duas tinham epidemiologia positiva para tuberculose. A pesquisa de bacilo álcool ácido resistente (BAAR), pelo método de Ziehl-Neelsen, entretanto, havia sido negativa em todos os casos. O diagnóstico etiológico nos três pacientes foi realizado pela identificação imunohistoquímica de bacilos tuberculínicos intracitoplasmáticos. COMENTÁRIOS: Baseando-se na elevada prevalência da tuberculose nos países em desenvovimento, associada ao aumento de sua incidência na última década, torna-se necessário considerá-la no diagnóstico diferencial das massas orbitárias em nosso meio. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2004-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/30847Revista do Instituto de Medicina Tropical de São Paulo; Vol. 46 No. 5 (2004); 291-294 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 46 Núm. 5 (2004); 291-294 Revista do Instituto de Medicina Tropical de São Paulo; v. 46 n. 5 (2004); 291-294 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/30847/32731Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessOliveira, Bráulio F.T.Takay, Fernanda C.Shida, Tatiana M.Santo, Ruth M.Souza Jr., Abelardo C.Matayoshi, Suzana2012-07-07T18:30:48Zoai:revistas.usp.br:article/30847Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:35.374882Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Orbital tuberculosis diagnosed by immunohistochemistry: case reports Tuberculose orbitária diagnosticada por imunohistoquímica |
title |
Orbital tuberculosis diagnosed by immunohistochemistry: case reports |
spellingShingle |
Orbital tuberculosis diagnosed by immunohistochemistry: case reports Oliveira, Bráulio F.T. Tuberculosis Orbit Diagnosis Immunochemistry |
title_short |
Orbital tuberculosis diagnosed by immunohistochemistry: case reports |
title_full |
Orbital tuberculosis diagnosed by immunohistochemistry: case reports |
title_fullStr |
Orbital tuberculosis diagnosed by immunohistochemistry: case reports |
title_full_unstemmed |
Orbital tuberculosis diagnosed by immunohistochemistry: case reports |
title_sort |
Orbital tuberculosis diagnosed by immunohistochemistry: case reports |
author |
Oliveira, Bráulio F.T. |
author_facet |
Oliveira, Bráulio F.T. Takay, Fernanda C. Shida, Tatiana M. Santo, Ruth M. Souza Jr., Abelardo C. Matayoshi, Suzana |
author_role |
author |
author2 |
Takay, Fernanda C. Shida, Tatiana M. Santo, Ruth M. Souza Jr., Abelardo C. Matayoshi, Suzana |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira, Bráulio F.T. Takay, Fernanda C. Shida, Tatiana M. Santo, Ruth M. Souza Jr., Abelardo C. Matayoshi, Suzana |
dc.subject.por.fl_str_mv |
Tuberculosis Orbit Diagnosis Immunochemistry |
topic |
Tuberculosis Orbit Diagnosis Immunochemistry |
description |
PURPOSE: To describe three cases of orbital tuberculosis, with their clinical characteristics and respective diagnostic procedures, showing the importance of histopathology for the correct diagnosis. PATIENTS AND METHODS: Three patients diagnosed and treated for orbital tuberculosis, in the "Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo" during the years of 1999 and 2001. RESULTS: All of the patients were female and referred a chronic evolution of swelling of one eyelid associated or not with other symptoms. They had not HIV infection. Two of them had positive epidemiology for tuberculosis. However, the search for systemic evidence of the disease and staining for bacilli (Ziehl-Neelsen method) were negative in all three patients. In all the cases, only the biopsy with immunohistochemical analysis could confirm the diagnosis. COMMENTS: Orbital involvement is a rare ocular manifestation of tuberculosis. Even in a tertiary hospital, few cases, if any, are diagnosed per year. However, the global incidence and prevalence of M. tuberculosis infections is not under control yet, and it has been a serious public health problem. Thus, one must be aware of the possibility of tuberculosis among the orbital diseases. |
publishDate |
2004 |
dc.date.none.fl_str_mv |
2004-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/30847 |
url |
https://www.revistas.usp.br/rimtsp/article/view/30847 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/30847/32731 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 46 No. 5 (2004); 291-294 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 46 Núm. 5 (2004); 291-294 Revista do Instituto de Medicina Tropical de São Paulo; v. 46 n. 5 (2004); 291-294 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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