Seroepidemiology of toxoplasmosis in women of childbearing age from a marginal community of Maracaibo, Venezuela

Detalhes bibliográficos
Autor(a) principal: Diaz-Suárez, Odelis
Data de Publicação: 2009
Outros Autores: Estevez, Jesus
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/31237
Resumo: The aim of this study was to determine the prevalence of anti-T. gondii total and IgM antibodies in women of childbearing age. One hundred serum samples of women were studied with age range from 11 to 45 years old. Samples were chosen by random. The determination of total antibodies was carried out through the indirect hemagglutination technique and IgM antibodies by ELISA's technique. The statistical analysis was carried out through the Chi square and the Spearman correlation tests. The theoretical estimated incidence of congenital toxoplasmosis was calculated, according to the annual increment of antibody prevalence among the age groups. The overall prevalence of toxoplasmosis was 33%, while only six individuals (18.2%) were positive to IgM. The highest prevalence was observed in the 11-35 year-old age group. The theoretical estimated incidence was 1.5 for 100 pregnancies in women of 21-25 year-old group; it decreased until 0.1% in the 41-45 year-old age group. The findings show a high prevalence of toxoplasmosis in this community with a high infection risk in women of the studied age group and the high cat population observed, suggesting that the transmission way by contaminated soils may play a main role in the spreading of toxoplasmosis in this community.
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spelling Seroepidemiology of toxoplasmosis in women of childbearing age from a marginal community of Maracaibo, Venezuela Soroepidemiologia da toxoplasmose em mulheres em idade fértil em comunidade marginal de Maracaibo, Venezuela ToxoplasmosisSeroprevalenceWomenAgeMarginal The aim of this study was to determine the prevalence of anti-T. gondii total and IgM antibodies in women of childbearing age. One hundred serum samples of women were studied with age range from 11 to 45 years old. Samples were chosen by random. The determination of total antibodies was carried out through the indirect hemagglutination technique and IgM antibodies by ELISA's technique. The statistical analysis was carried out through the Chi square and the Spearman correlation tests. The theoretical estimated incidence of congenital toxoplasmosis was calculated, according to the annual increment of antibody prevalence among the age groups. The overall prevalence of toxoplasmosis was 33%, while only six individuals (18.2%) were positive to IgM. The highest prevalence was observed in the 11-35 year-old age group. The theoretical estimated incidence was 1.5 for 100 pregnancies in women of 21-25 year-old group; it decreased until 0.1% in the 41-45 year-old age group. The findings show a high prevalence of toxoplasmosis in this community with a high infection risk in women of the studied age group and the high cat population observed, suggesting that the transmission way by contaminated soils may play a main role in the spreading of toxoplasmosis in this community. A finalidade do presente estudo foi determinar a prevalência de anticorpos totais e IgM anti-Toxoplasma gondii, em mulheres em idade fértil. Estudaram-se 100 amostras de soro de mulheres com idade entre 11 e 45 anos. Amostras foram escolhidas ao acaso. A determinação de anticorpos totais foi realizada com a técnica de hemaglutinação indireta e a determinação de anticorpos IgM, pela técnica de ELISA. A análise estatística foi realizada usando a prova do Chi quadrado e a correlação de Spearman. A incidência teórica estimada da toxoplasmose congênita foi calculada de acordo com o incremento anual da prevalência de anticorpos entre os diversos grupos de acordo com a idade. A prevalência geral de toxoplasmose foi de 33%, enquanto somente seis pacientes (l8,2%) foram positivos para IgM. A prevalência maior foi observada no grupo de 11-35 anos de idade. A incidência teórica estimada foi de 1,5 por 100 mulheres grávidas no grupo de 21-25 anos de idade; diminuiu até 0,1% no grupo de 41-45 anos de idade. Os resultados obtidos refletem alta prevalência de toxoplasmose nesta comunidade, além de alto risco de infecção nas mulheres no grupo de idade estudado, sugerindo-se que a transmissão através de fezes de gato, pode ter papel preponderante. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2009-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/31237Revista do Instituto de Medicina Tropical de São Paulo; Vol. 51 No. 1 (2009); 13-17 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 51 Núm. 1 (2009); 13-17 Revista do Instituto de Medicina Tropical de São Paulo; v. 51 n. 1 (2009); 13-17 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/31237/33121Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessDiaz-Suárez, OdelisEstevez, Jesus2012-07-07T19:19:56Zoai:revistas.usp.br:article/31237Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:55.181663Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Seroepidemiology of toxoplasmosis in women of childbearing age from a marginal community of Maracaibo, Venezuela
Soroepidemiologia da toxoplasmose em mulheres em idade fértil em comunidade marginal de Maracaibo, Venezuela
title Seroepidemiology of toxoplasmosis in women of childbearing age from a marginal community of Maracaibo, Venezuela
spellingShingle Seroepidemiology of toxoplasmosis in women of childbearing age from a marginal community of Maracaibo, Venezuela
Diaz-Suárez, Odelis
Toxoplasmosis
Seroprevalence
Women
Age
Marginal
title_short Seroepidemiology of toxoplasmosis in women of childbearing age from a marginal community of Maracaibo, Venezuela
title_full Seroepidemiology of toxoplasmosis in women of childbearing age from a marginal community of Maracaibo, Venezuela
title_fullStr Seroepidemiology of toxoplasmosis in women of childbearing age from a marginal community of Maracaibo, Venezuela
title_full_unstemmed Seroepidemiology of toxoplasmosis in women of childbearing age from a marginal community of Maracaibo, Venezuela
title_sort Seroepidemiology of toxoplasmosis in women of childbearing age from a marginal community of Maracaibo, Venezuela
author Diaz-Suárez, Odelis
author_facet Diaz-Suárez, Odelis
Estevez, Jesus
author_role author
author2 Estevez, Jesus
author2_role author
dc.contributor.author.fl_str_mv Diaz-Suárez, Odelis
Estevez, Jesus
dc.subject.por.fl_str_mv Toxoplasmosis
Seroprevalence
Women
Age
Marginal
topic Toxoplasmosis
Seroprevalence
Women
Age
Marginal
description The aim of this study was to determine the prevalence of anti-T. gondii total and IgM antibodies in women of childbearing age. One hundred serum samples of women were studied with age range from 11 to 45 years old. Samples were chosen by random. The determination of total antibodies was carried out through the indirect hemagglutination technique and IgM antibodies by ELISA's technique. The statistical analysis was carried out through the Chi square and the Spearman correlation tests. The theoretical estimated incidence of congenital toxoplasmosis was calculated, according to the annual increment of antibody prevalence among the age groups. The overall prevalence of toxoplasmosis was 33%, while only six individuals (18.2%) were positive to IgM. The highest prevalence was observed in the 11-35 year-old age group. The theoretical estimated incidence was 1.5 for 100 pregnancies in women of 21-25 year-old group; it decreased until 0.1% in the 41-45 year-old age group. The findings show a high prevalence of toxoplasmosis in this community with a high infection risk in women of the studied age group and the high cat population observed, suggesting that the transmission way by contaminated soils may play a main role in the spreading of toxoplasmosis in this community.
publishDate 2009
dc.date.none.fl_str_mv 2009-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/31237
url https://www.revistas.usp.br/rimtsp/article/view/31237
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/31237/33121
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 51 No. 1 (2009); 13-17
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 51 Núm. 1 (2009); 13-17
Revista do Instituto de Medicina Tropical de São Paulo; v. 51 n. 1 (2009); 13-17
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
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reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
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