Investigação sobre a passagem transplacentária de microfilárias de Wuchereria bancrofti em recém-nascidos de mães microfilarêmicas

• Autor(a) principal: Pires, Maria Luiza
• Data de Publicação: 1991
• Outros Autores: Santos Ferreira, Rita, Araújo, Sérgio, Albuquerque, Roberta, Remigio Neto, José, Simões da Silva, Adeildo, Dreyer, Gerusa
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
• Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/28799
• topic: Wuchereria bancrofti; Microfilaremia; Passagem transplacentária; Leite materno

The occurrence of circulating Wuchereria bancrofti microfilariae was investigated in 304 pregnant women from the "Unidade Mista Pof. Barros Lima" and "Hospital das Clinicas/UF-PE". The filtration technique was employed to detect microfilaraemia during pregnancy, and 13 women were found to be positive (4.2%). The investigation of microfilariae in the cord blood of their children was negative (6/13), and also in venous blood samples colected up to 72 hours after birth and with 6 months of life. Milk samples from these mothers also had no microfilariae. The authors suggest that the occurrence of placentary lesions may be a possible factor involved in the transplacental transfer of microfilariae, and that in utero exposure to microfilariae and/or filarial antigens may influence the response to a filarial infection acquired later, thus being important a clinical and laboratorial follow-up of children exposed previously to filarial antigens during early periods of human development.