American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice

Detalhes bibliográficos
Autor(a) principal: Silva, Marcelo E.
Data de Publicação: 1987
Outros Autores: Evangelista, Elizio A., Nicoli, Jacques R., Bambirra, Eduardo A., Vieira, Enio C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/28532
Resumo: Germfree (GF) and conventional (CV) CFW (LOB) mice and Wistar and Sprague-Dawley rats were infected with Trypanosoma cruzi. The disease was more severe in the GF than in the CV animals as revealed by: (1) an earlier and more intense parasitemia; (2) a more precocious mortality; (3) a twice enlarged spleen: (4) a more intense cell and tissue parasitism; (5) visceral signs of cardiac failure.
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spelling American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice Tripanosomíase americana (doença de Chagas) em ratos e camundongos convencionais e isentos de germes Chagas' diseaseTrypanosomiasisGermfree ratsGermfree mice Germfree (GF) and conventional (CV) CFW (LOB) mice and Wistar and Sprague-Dawley rats were infected with Trypanosoma cruzi. The disease was more severe in the GF than in the CV animals as revealed by: (1) an earlier and more intense parasitemia; (2) a more precocious mortality; (3) a twice enlarged spleen: (4) a more intense cell and tissue parasitism; (5) visceral signs of cardiac failure. Camundongos CFW (LOB) e ratos Wistar e Sprague-Dawley isentos de germes (GF) e convencionais (CV) foram infectados com Trypanosoma cruzi. A doença foi mais grave nos animais GF do que nos CV, o que foi demonstrado por: (1) uma parasitemia mais precoce e mais intensa: (2) uma mortalidade mais precoce: (3) baço duas vezes maior; (4) um parasitismo celular e tissular mais intenso; (5) sinais viscerais de insuficiência cardíaca. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1987-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/28532Revista do Instituto de Medicina Tropical de São Paulo; Vol. 29 No. 5 (1987); 284-288 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 29 Núm. 5 (1987); 284-288 Revista do Instituto de Medicina Tropical de São Paulo; v. 29 n. 5 (1987); 284-288 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/28532/30385Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessSilva, Marcelo E.Evangelista, Elizio A.Nicoli, Jacques R.Bambirra, Eduardo A.Vieira, Enio C.2012-07-02T00:58:19Zoai:revistas.usp.br:article/28532Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:50:15.872344Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice
Tripanosomíase americana (doença de Chagas) em ratos e camundongos convencionais e isentos de germes
title American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice
spellingShingle American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice
Silva, Marcelo E.
Chagas' disease
Trypanosomiasis
Germfree rats
Germfree mice
title_short American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice
title_full American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice
title_fullStr American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice
title_full_unstemmed American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice
title_sort American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice
author Silva, Marcelo E.
author_facet Silva, Marcelo E.
Evangelista, Elizio A.
Nicoli, Jacques R.
Bambirra, Eduardo A.
Vieira, Enio C.
author_role author
author2 Evangelista, Elizio A.
Nicoli, Jacques R.
Bambirra, Eduardo A.
Vieira, Enio C.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silva, Marcelo E.
Evangelista, Elizio A.
Nicoli, Jacques R.
Bambirra, Eduardo A.
Vieira, Enio C.
dc.subject.por.fl_str_mv Chagas' disease
Trypanosomiasis
Germfree rats
Germfree mice
topic Chagas' disease
Trypanosomiasis
Germfree rats
Germfree mice
description Germfree (GF) and conventional (CV) CFW (LOB) mice and Wistar and Sprague-Dawley rats were infected with Trypanosoma cruzi. The disease was more severe in the GF than in the CV animals as revealed by: (1) an earlier and more intense parasitemia; (2) a more precocious mortality; (3) a twice enlarged spleen: (4) a more intense cell and tissue parasitism; (5) visceral signs of cardiac failure.
publishDate 1987
dc.date.none.fl_str_mv 1987-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/28532
url https://www.revistas.usp.br/rimtsp/article/view/28532
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/28532/30385
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 29 No. 5 (1987); 284-288
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 29 Núm. 5 (1987); 284-288
Revista do Instituto de Medicina Tropical de São Paulo; v. 29 n. 5 (1987); 284-288
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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