Schistosoma mansoni: quantitative aspects of the evolution of gamma-irradiated cercariae at the skin, lungs, and portal system, in mice

Detalhes bibliográficos
Autor(a) principal: Cardoso, Gileno de Sá
Data de Publicação: 1989
Outros Autores: Coelho, Paulo Marcos Zech
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/28682
Resumo: The migration of Schistosoma mansoni (LE and SJ strains) has been studied in eight groups of outbred Swiss albino mice (Mus musculus), which were previously infected with ca 450 cercariae, transcutaneously. The infection of mice was performed with non irradiated cercariae (control groups), or with gamma-irradiated cercariae, at the schedule of 3, 20 and 40 Krad. Regarding the skin, a progressive decrease was detected for the recovery rates, related to the time of infection. As far as the lungs and portal system are concerned, a significant inverse correlation was observed between the total recovery rate and the irradiation dosages. The dose of 20 Krad practically hinders the migration of the parasites (in both strains) from the lungs to the portal system, whereas the dose of 40 Krad prevents the migration of most of the parasites from the skin to the lungs.
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spelling Schistosoma mansoni: quantitative aspects of the evolution of gamma-irradiated cercariae at the skin, lungs, and portal system, in mice Schistosoma mansoni: aspectos quantitativos da evolução de cercarias irradiadas a nível da pele, pulmões e sistema porta, em camundongos Schistosoma mansoniIrradiação de cercariasEvolução de vermes irradiados The migration of Schistosoma mansoni (LE and SJ strains) has been studied in eight groups of outbred Swiss albino mice (Mus musculus), which were previously infected with ca 450 cercariae, transcutaneously. The infection of mice was performed with non irradiated cercariae (control groups), or with gamma-irradiated cercariae, at the schedule of 3, 20 and 40 Krad. Regarding the skin, a progressive decrease was detected for the recovery rates, related to the time of infection. As far as the lungs and portal system are concerned, a significant inverse correlation was observed between the total recovery rate and the irradiation dosages. The dose of 20 Krad practically hinders the migration of the parasites (in both strains) from the lungs to the portal system, whereas the dose of 40 Krad prevents the migration of most of the parasites from the skin to the lungs. Foi estudada a migração do Schistosoma mansoni (cepas LE e SJ) em oito grupos de camundongos albinos (Mus musculus) não isogênicos, infectados transcutaneamente com cerca de 450 cercarias não irradiadas (grupos controles) e irradiadas com 3 Krad, 20 Krad e 40 Krad de radiação gama proveniente de cobalto-60, Na pele, observou-se uma diminuição progressiva das taxas de recuperação em função do tempo e, nos pulmões e sistema porta, verificou-se uma relação inversa significativa entre as taxas de recuperação total e as doses de irradiação. A dose de 20 Krad praticamente impede a migração dos parasites, de ambas as cepas, dos pulmões até o sistema porta, enquanto a de 40 Krad praticamente impede a migração dos mesmos da pele para os pulmões. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1989-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/28682Revista do Instituto de Medicina Tropical de São Paulo; Vol. 31 No. 5 (1989); 313-321 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 31 Núm. 5 (1989); 313-321 Revista do Instituto de Medicina Tropical de São Paulo; v. 31 n. 5 (1989); 313-321 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTporhttps://www.revistas.usp.br/rimtsp/article/view/28682/30535Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessCardoso, Gileno de SáCoelho, Paulo Marcos Zech2012-07-02T01:11:03Zoai:revistas.usp.br:article/28682Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:50:25.858014Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Schistosoma mansoni: quantitative aspects of the evolution of gamma-irradiated cercariae at the skin, lungs, and portal system, in mice
Schistosoma mansoni: aspectos quantitativos da evolução de cercarias irradiadas a nível da pele, pulmões e sistema porta, em camundongos
title Schistosoma mansoni: quantitative aspects of the evolution of gamma-irradiated cercariae at the skin, lungs, and portal system, in mice
spellingShingle Schistosoma mansoni: quantitative aspects of the evolution of gamma-irradiated cercariae at the skin, lungs, and portal system, in mice
Cardoso, Gileno de Sá
Schistosoma mansoni
Irradiação de cercarias
Evolução de vermes irradiados
title_short Schistosoma mansoni: quantitative aspects of the evolution of gamma-irradiated cercariae at the skin, lungs, and portal system, in mice
title_full Schistosoma mansoni: quantitative aspects of the evolution of gamma-irradiated cercariae at the skin, lungs, and portal system, in mice
title_fullStr Schistosoma mansoni: quantitative aspects of the evolution of gamma-irradiated cercariae at the skin, lungs, and portal system, in mice
title_full_unstemmed Schistosoma mansoni: quantitative aspects of the evolution of gamma-irradiated cercariae at the skin, lungs, and portal system, in mice
title_sort Schistosoma mansoni: quantitative aspects of the evolution of gamma-irradiated cercariae at the skin, lungs, and portal system, in mice
author Cardoso, Gileno de Sá
author_facet Cardoso, Gileno de Sá
Coelho, Paulo Marcos Zech
author_role author
author2 Coelho, Paulo Marcos Zech
author2_role author
dc.contributor.author.fl_str_mv Cardoso, Gileno de Sá
Coelho, Paulo Marcos Zech
dc.subject.por.fl_str_mv Schistosoma mansoni
Irradiação de cercarias
Evolução de vermes irradiados
topic Schistosoma mansoni
Irradiação de cercarias
Evolução de vermes irradiados
description The migration of Schistosoma mansoni (LE and SJ strains) has been studied in eight groups of outbred Swiss albino mice (Mus musculus), which were previously infected with ca 450 cercariae, transcutaneously. The infection of mice was performed with non irradiated cercariae (control groups), or with gamma-irradiated cercariae, at the schedule of 3, 20 and 40 Krad. Regarding the skin, a progressive decrease was detected for the recovery rates, related to the time of infection. As far as the lungs and portal system are concerned, a significant inverse correlation was observed between the total recovery rate and the irradiation dosages. The dose of 20 Krad practically hinders the migration of the parasites (in both strains) from the lungs to the portal system, whereas the dose of 40 Krad prevents the migration of most of the parasites from the skin to the lungs.
publishDate 1989
dc.date.none.fl_str_mv 1989-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/28682
url https://www.revistas.usp.br/rimtsp/article/view/28682
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/28682/30535
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 31 No. 5 (1989); 313-321
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 31 Núm. 5 (1989); 313-321
Revista do Instituto de Medicina Tropical de São Paulo; v. 31 n. 5 (1989); 313-321
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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