Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature review
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/210783 |
Resumo: | Acid-fast bacteria can be implicated in skin and soft tissue infections. Diagnostic identification can be challenging or not feasible by routine laboratory techniques, especially if there is no access to the Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) technology. Here, we present two cases of skin and soft tissue infections caused by two different acid-fast bacteria, Nocardia brasiliensis and Mycobacterium marinum. They both grew on Löwenstein–Jensen medium, Sabouraud agar medium and blood agar medium. Both bacteria appeared acid-fast by Ziehl–Neelsen stain and Gram-positive by Gram stain. The identification was performed by MALDI-TOF MS and gene analysis. N. brasiliensis and nontuberculous mycobacterium M. marinum represent rare pathogens that cause severe skin and soft tissue infections. Failure to identify the causative agent and subsequent inappropriate or inadequate treatment may lead to severe complications or even disseminated disease, especially in immunocompromised individuals. |
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Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature reviewNocardia brasiliensisMycobacterium marinumZiehl–Neelsen stainAcid-fast bacteriaSkin and soft tissue infectionsMALDI-TOF MSAcid-fast bacteria can be implicated in skin and soft tissue infections. Diagnostic identification can be challenging or not feasible by routine laboratory techniques, especially if there is no access to the Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) technology. Here, we present two cases of skin and soft tissue infections caused by two different acid-fast bacteria, Nocardia brasiliensis and Mycobacterium marinum. They both grew on Löwenstein–Jensen medium, Sabouraud agar medium and blood agar medium. Both bacteria appeared acid-fast by Ziehl–Neelsen stain and Gram-positive by Gram stain. The identification was performed by MALDI-TOF MS and gene analysis. N. brasiliensis and nontuberculous mycobacterium M. marinum represent rare pathogens that cause severe skin and soft tissue infections. Failure to identify the causative agent and subsequent inappropriate or inadequate treatment may lead to severe complications or even disseminated disease, especially in immunocompromised individuals.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2023-04-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/21078310.1590/S1678-9946202365029Revista do Instituto de Medicina Tropical de São Paulo; Vol. 65 (2023); e29Revista do Instituto de Medicina Tropical de São Paulo; v. 65 (2023); e29Revista do Instituto de Medicina Tropical de São Paulo; Vol. 65 (2023); e291678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/210783/193229Copyright (c) 2023 Anastasia Spiliopoulou, Georgia Kyriakou, Sophia Georgiou, Alexandra Lekkou, Lydia Leonidou, Maria Militsopoulou, Eleni Papadogeorgaki, Myrto Christofidou, Fevronia Kolonitsiou, Fotini Paliogiannihttps://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessSpiliopoulou, Anastasia Kyriakou, Georgia Georgiou, Sophia Lekkou, Alexandra Leonidou, Lydia Militsopoulou, Maria Papadogeorgaki, Eleni Christofidou, Myrto Kolonitsiou, Fevronia Paliogianni, Fotini 2023-04-20T14:35:03Zoai:revistas.usp.br:article/210783Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2023-04-20T14:35:03Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)false |
dc.title.none.fl_str_mv |
Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature review |
title |
Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature review |
spellingShingle |
Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature review Spiliopoulou, Anastasia Nocardia brasiliensis Mycobacterium marinum Ziehl–Neelsen stain Acid-fast bacteria Skin and soft tissue infections MALDI-TOF MS |
title_short |
Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature review |
title_full |
Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature review |
title_fullStr |
Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature review |
title_full_unstemmed |
Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature review |
title_sort |
Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature review |
author |
Spiliopoulou, Anastasia |
author_facet |
Spiliopoulou, Anastasia Kyriakou, Georgia Georgiou, Sophia Lekkou, Alexandra Leonidou, Lydia Militsopoulou, Maria Papadogeorgaki, Eleni Christofidou, Myrto Kolonitsiou, Fevronia Paliogianni, Fotini |
author_role |
author |
author2 |
Kyriakou, Georgia Georgiou, Sophia Lekkou, Alexandra Leonidou, Lydia Militsopoulou, Maria Papadogeorgaki, Eleni Christofidou, Myrto Kolonitsiou, Fevronia Paliogianni, Fotini |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Spiliopoulou, Anastasia Kyriakou, Georgia Georgiou, Sophia Lekkou, Alexandra Leonidou, Lydia Militsopoulou, Maria Papadogeorgaki, Eleni Christofidou, Myrto Kolonitsiou, Fevronia Paliogianni, Fotini |
dc.subject.por.fl_str_mv |
Nocardia brasiliensis Mycobacterium marinum Ziehl–Neelsen stain Acid-fast bacteria Skin and soft tissue infections MALDI-TOF MS |
topic |
Nocardia brasiliensis Mycobacterium marinum Ziehl–Neelsen stain Acid-fast bacteria Skin and soft tissue infections MALDI-TOF MS |
description |
Acid-fast bacteria can be implicated in skin and soft tissue infections. Diagnostic identification can be challenging or not feasible by routine laboratory techniques, especially if there is no access to the Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) technology. Here, we present two cases of skin and soft tissue infections caused by two different acid-fast bacteria, Nocardia brasiliensis and Mycobacterium marinum. They both grew on Löwenstein–Jensen medium, Sabouraud agar medium and blood agar medium. Both bacteria appeared acid-fast by Ziehl–Neelsen stain and Gram-positive by Gram stain. The identification was performed by MALDI-TOF MS and gene analysis. N. brasiliensis and nontuberculous mycobacterium M. marinum represent rare pathogens that cause severe skin and soft tissue infections. Failure to identify the causative agent and subsequent inappropriate or inadequate treatment may lead to severe complications or even disseminated disease, especially in immunocompromised individuals. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-04-19 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/210783 10.1590/S1678-9946202365029 |
url |
https://www.revistas.usp.br/rimtsp/article/view/210783 |
identifier_str_mv |
10.1590/S1678-9946202365029 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/210783/193229 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 65 (2023); e29 Revista do Instituto de Medicina Tropical de São Paulo; v. 65 (2023); e29 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 65 (2023); e29 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
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1798951636578598912 |