Feo-hifomicose subcutânea por Exophiala jeanselmei: registro de três casos em transplantados renais

• Autor(a) principal: Sabbaga, Emil
• Data de Publicação: 1994
• Outros Autores: Tedesco-Marchesi, Leontina Margarido, Lacaz, Carlos da Silva, Cucé, Luiz Carlos, Salebian, Alberto, Heins-Vaccari, Elisabeth Maria, Sotto, Miriam Nacagami, Valente, Neusa Yuriko Sakai, Porto, Edward, Levy Neto, Maurício
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
• Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/29144
• topic: Feo-hifornicose; Feo-hifornicose subcutânea; Exophiala jeanselmei; Transplantados renais

We report three cases of subcutaneous phaeohy-phomycosis due to Exophiala jeanselmei (Langeron) McGinnis et Padhye 1977, in kidney transplant patients. Exophiala jeanselmei is a dematious fungus having also ability to rarely procedure eumycetoma (black grains). According to KWON-CHUNG & BENNETT (1992)27 such fungus is antigenically very heterogeneous, since so far three serotypes have been identified; each serotype including subgroups. Subcutaneous phaeohyphomycosis is becoming more and more frequent in kidney transplant patients submitted to an immunosupressive treatment. As Exophiala jeanselmei has already been isolated from the environment it becomes difficult to explain the pathogenicity of these cases by a reactivation of quiescent processes. The authors suggest an occasional fungistatic action of cyclosporine A upon Exophiala jeanselmei. A review of the literature was carried out with the report mainly of cases published in Brazil.