Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study

Detalhes bibliográficos
Autor(a) principal: Pires, Cássia de Paula
Data de Publicação: 2024
Outros Autores: Mareto, Lisany Krug, Medeiros, Márcio José de, Oliveira, Everton Falcão de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/224305
Resumo: Maternal and child health remains an enduring global challenge, having occupied a prominent position on international agendas since the dawn of the 21st century. During pregnancy, syphilis emerges as the second most prevalent cause of stillbirth on a global scale, potentially leading to a range of adverse outcomes. This study aimed to describe the clinical and epidemiological profile of cases of gestational and congenital syphilis and the hospital care provided for newborns in Campo Grande municipality, Mato Grosso do Sul State, Brazil, from 2013 to 2018. This is a cross-sectional study based on data from Brazilian Notifiable Diseases Surveillance System (SINAN) and hospital medical records. Chi-square or Fisher’s exact test and logistic regression analysis were used to assess the associations and relationships between the child’s clinical outcome at birth and the mother’s clinical-obstetric and epidemiological characteristics. Cumulative detection rate of gestational syphilis was 174.3 cases per 1,000 live births and cumulative incidence of congenital syphilis was 47.7 cases per 1,000 live births. Alcoholism, prenatal care, number of prenatal visits, maternal treatment regimen, and timing of maternal diagnosis were associated with child’s clinical outcome at birth and considered in the regression model. Prenatal visits showed a protective effect against the signs and symptoms of congenital syphilis (odds ratio = 0.37; 95% confidence interval = 0.17−0.77). Medical assistance was considered inadequate in 62.3% of cases. Prenatal consultations should be encouraged among pregnant women. There is a need for better education of health personnel on the treatment and diagnosis of syphilis.
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spelling Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional studyGestational syphilisCongenital syphilisVertical transmissionPrenatal careMaternal and child health remains an enduring global challenge, having occupied a prominent position on international agendas since the dawn of the 21st century. During pregnancy, syphilis emerges as the second most prevalent cause of stillbirth on a global scale, potentially leading to a range of adverse outcomes. This study aimed to describe the clinical and epidemiological profile of cases of gestational and congenital syphilis and the hospital care provided for newborns in Campo Grande municipality, Mato Grosso do Sul State, Brazil, from 2013 to 2018. This is a cross-sectional study based on data from Brazilian Notifiable Diseases Surveillance System (SINAN) and hospital medical records. Chi-square or Fisher’s exact test and logistic regression analysis were used to assess the associations and relationships between the child’s clinical outcome at birth and the mother’s clinical-obstetric and epidemiological characteristics. Cumulative detection rate of gestational syphilis was 174.3 cases per 1,000 live births and cumulative incidence of congenital syphilis was 47.7 cases per 1,000 live births. Alcoholism, prenatal care, number of prenatal visits, maternal treatment regimen, and timing of maternal diagnosis were associated with child’s clinical outcome at birth and considered in the regression model. Prenatal visits showed a protective effect against the signs and symptoms of congenital syphilis (odds ratio = 0.37; 95% confidence interval = 0.17−0.77). Medical assistance was considered inadequate in 62.3% of cases. Prenatal consultations should be encouraged among pregnant women. There is a need for better education of health personnel on the treatment and diagnosis of syphilis.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2024-04-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/22430510.1590/Revista do Instituto de Medicina Tropical de São Paulo; Vol. 66 (2024); e21Revista do Instituto de Medicina Tropical de São Paulo; v. 66 (2024); e21Revista do Instituto de Medicina Tropical de São Paulo; Vol. 66 (2024); e211678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/224305/203908Copyright (c) 2024 Cássia de Paula Pires, Lisany Krug Mareto, Márcio José de Medeiros, Everton Falcão de Oliveirahttps://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessPires, Cássia de PaulaMareto, Lisany KrugMedeiros, Márcio José deOliveira, Everton Falcão de2024-05-06T14:04:52Zoai:revistas.usp.br:article/224305Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2024-05-06T14:04:52Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)false
dc.title.none.fl_str_mv Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study
title Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study
spellingShingle Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study
Pires, Cássia de Paula
Gestational syphilis
Congenital syphilis
Vertical transmission
Prenatal care
title_short Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study
title_full Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study
title_fullStr Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study
title_full_unstemmed Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study
title_sort Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study
author Pires, Cássia de Paula
author_facet Pires, Cássia de Paula
Mareto, Lisany Krug
Medeiros, Márcio José de
Oliveira, Everton Falcão de
author_role author
author2 Mareto, Lisany Krug
Medeiros, Márcio José de
Oliveira, Everton Falcão de
author2_role author
author
author
dc.contributor.author.fl_str_mv Pires, Cássia de Paula
Mareto, Lisany Krug
Medeiros, Márcio José de
Oliveira, Everton Falcão de
dc.subject.por.fl_str_mv Gestational syphilis
Congenital syphilis
Vertical transmission
Prenatal care
topic Gestational syphilis
Congenital syphilis
Vertical transmission
Prenatal care
description Maternal and child health remains an enduring global challenge, having occupied a prominent position on international agendas since the dawn of the 21st century. During pregnancy, syphilis emerges as the second most prevalent cause of stillbirth on a global scale, potentially leading to a range of adverse outcomes. This study aimed to describe the clinical and epidemiological profile of cases of gestational and congenital syphilis and the hospital care provided for newborns in Campo Grande municipality, Mato Grosso do Sul State, Brazil, from 2013 to 2018. This is a cross-sectional study based on data from Brazilian Notifiable Diseases Surveillance System (SINAN) and hospital medical records. Chi-square or Fisher’s exact test and logistic regression analysis were used to assess the associations and relationships between the child’s clinical outcome at birth and the mother’s clinical-obstetric and epidemiological characteristics. Cumulative detection rate of gestational syphilis was 174.3 cases per 1,000 live births and cumulative incidence of congenital syphilis was 47.7 cases per 1,000 live births. Alcoholism, prenatal care, number of prenatal visits, maternal treatment regimen, and timing of maternal diagnosis were associated with child’s clinical outcome at birth and considered in the regression model. Prenatal visits showed a protective effect against the signs and symptoms of congenital syphilis (odds ratio = 0.37; 95% confidence interval = 0.17−0.77). Medical assistance was considered inadequate in 62.3% of cases. Prenatal consultations should be encouraged among pregnant women. There is a need for better education of health personnel on the treatment and diagnosis of syphilis.
publishDate 2024
dc.date.none.fl_str_mv 2024-04-25
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dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/224305
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/224305/203908
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by-nc/4.0
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rights_invalid_str_mv https://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 66 (2024); e21
Revista do Instituto de Medicina Tropical de São Paulo; v. 66 (2024); e21
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 66 (2024); e21
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
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reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
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