Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/224305 |
Resumo: | Maternal and child health remains an enduring global challenge, having occupied a prominent position on international agendas since the dawn of the 21st century. During pregnancy, syphilis emerges as the second most prevalent cause of stillbirth on a global scale, potentially leading to a range of adverse outcomes. This study aimed to describe the clinical and epidemiological profile of cases of gestational and congenital syphilis and the hospital care provided for newborns in Campo Grande municipality, Mato Grosso do Sul State, Brazil, from 2013 to 2018. This is a cross-sectional study based on data from Brazilian Notifiable Diseases Surveillance System (SINAN) and hospital medical records. Chi-square or Fisher’s exact test and logistic regression analysis were used to assess the associations and relationships between the child’s clinical outcome at birth and the mother’s clinical-obstetric and epidemiological characteristics. Cumulative detection rate of gestational syphilis was 174.3 cases per 1,000 live births and cumulative incidence of congenital syphilis was 47.7 cases per 1,000 live births. Alcoholism, prenatal care, number of prenatal visits, maternal treatment regimen, and timing of maternal diagnosis were associated with child’s clinical outcome at birth and considered in the regression model. Prenatal visits showed a protective effect against the signs and symptoms of congenital syphilis (odds ratio = 0.37; 95% confidence interval = 0.17−0.77). Medical assistance was considered inadequate in 62.3% of cases. Prenatal consultations should be encouraged among pregnant women. There is a need for better education of health personnel on the treatment and diagnosis of syphilis. |
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Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional studyGestational syphilisCongenital syphilisVertical transmissionPrenatal careMaternal and child health remains an enduring global challenge, having occupied a prominent position on international agendas since the dawn of the 21st century. During pregnancy, syphilis emerges as the second most prevalent cause of stillbirth on a global scale, potentially leading to a range of adverse outcomes. This study aimed to describe the clinical and epidemiological profile of cases of gestational and congenital syphilis and the hospital care provided for newborns in Campo Grande municipality, Mato Grosso do Sul State, Brazil, from 2013 to 2018. This is a cross-sectional study based on data from Brazilian Notifiable Diseases Surveillance System (SINAN) and hospital medical records. Chi-square or Fisher’s exact test and logistic regression analysis were used to assess the associations and relationships between the child’s clinical outcome at birth and the mother’s clinical-obstetric and epidemiological characteristics. Cumulative detection rate of gestational syphilis was 174.3 cases per 1,000 live births and cumulative incidence of congenital syphilis was 47.7 cases per 1,000 live births. Alcoholism, prenatal care, number of prenatal visits, maternal treatment regimen, and timing of maternal diagnosis were associated with child’s clinical outcome at birth and considered in the regression model. Prenatal visits showed a protective effect against the signs and symptoms of congenital syphilis (odds ratio = 0.37; 95% confidence interval = 0.17−0.77). Medical assistance was considered inadequate in 62.3% of cases. Prenatal consultations should be encouraged among pregnant women. There is a need for better education of health personnel on the treatment and diagnosis of syphilis.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2024-04-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/22430510.1590/Revista do Instituto de Medicina Tropical de São Paulo; Vol. 66 (2024); e21Revista do Instituto de Medicina Tropical de São Paulo; v. 66 (2024); e21Revista do Instituto de Medicina Tropical de São Paulo; Vol. 66 (2024); e211678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/224305/203908Copyright (c) 2024 Cássia de Paula Pires, Lisany Krug Mareto, Márcio José de Medeiros, Everton Falcão de Oliveirahttps://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessPires, Cássia de PaulaMareto, Lisany KrugMedeiros, Márcio José deOliveira, Everton Falcão de2024-05-06T14:04:52Zoai:revistas.usp.br:article/224305Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2024-05-06T14:04:52Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)false |
dc.title.none.fl_str_mv |
Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study |
title |
Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study |
spellingShingle |
Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study Pires, Cássia de Paula Gestational syphilis Congenital syphilis Vertical transmission Prenatal care |
title_short |
Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study |
title_full |
Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study |
title_fullStr |
Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study |
title_full_unstemmed |
Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study |
title_sort |
Associated factors, incidence, and management of gestational and congenital syphilis in a Brazilian state capital: a cross-sectional study |
author |
Pires, Cássia de Paula |
author_facet |
Pires, Cássia de Paula Mareto, Lisany Krug Medeiros, Márcio José de Oliveira, Everton Falcão de |
author_role |
author |
author2 |
Mareto, Lisany Krug Medeiros, Márcio José de Oliveira, Everton Falcão de |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Pires, Cássia de Paula Mareto, Lisany Krug Medeiros, Márcio José de Oliveira, Everton Falcão de |
dc.subject.por.fl_str_mv |
Gestational syphilis Congenital syphilis Vertical transmission Prenatal care |
topic |
Gestational syphilis Congenital syphilis Vertical transmission Prenatal care |
description |
Maternal and child health remains an enduring global challenge, having occupied a prominent position on international agendas since the dawn of the 21st century. During pregnancy, syphilis emerges as the second most prevalent cause of stillbirth on a global scale, potentially leading to a range of adverse outcomes. This study aimed to describe the clinical and epidemiological profile of cases of gestational and congenital syphilis and the hospital care provided for newborns in Campo Grande municipality, Mato Grosso do Sul State, Brazil, from 2013 to 2018. This is a cross-sectional study based on data from Brazilian Notifiable Diseases Surveillance System (SINAN) and hospital medical records. Chi-square or Fisher’s exact test and logistic regression analysis were used to assess the associations and relationships between the child’s clinical outcome at birth and the mother’s clinical-obstetric and epidemiological characteristics. Cumulative detection rate of gestational syphilis was 174.3 cases per 1,000 live births and cumulative incidence of congenital syphilis was 47.7 cases per 1,000 live births. Alcoholism, prenatal care, number of prenatal visits, maternal treatment regimen, and timing of maternal diagnosis were associated with child’s clinical outcome at birth and considered in the regression model. Prenatal visits showed a protective effect against the signs and symptoms of congenital syphilis (odds ratio = 0.37; 95% confidence interval = 0.17−0.77). Medical assistance was considered inadequate in 62.3% of cases. Prenatal consultations should be encouraged among pregnant women. There is a need for better education of health personnel on the treatment and diagnosis of syphilis. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-04-25 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/224305 10.1590/ |
url |
https://www.revistas.usp.br/rimtsp/article/view/224305 |
identifier_str_mv |
10.1590/ |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/224305/203908 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 66 (2024); e21 Revista do Instituto de Medicina Tropical de São Paulo; v. 66 (2024); e21 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 66 (2024); e21 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
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Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
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||revimtsp@usp.br |
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