Atividade antifúngica de nanopartículas de prata obtidas por síntese verde

Detalhes bibliográficos
Autor(a) principal: MALLMANN, Eduardo José J.
Data de Publicação: 2015
Outros Autores: CUNHA, Francisco Afrânio, CASTRO, Bruno N.M.F., MACIEL, Auberson Martins, MENEZES, Everardo Albuquerque, FECHINE, Pierre Basílio Almeida
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/100972
Resumo: Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.
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spelling Atividade antifúngica de nanopartículas de prata obtidas por síntese verde ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment. Nanopartículas de Prata (AgNPs) são estruturas metálicas em escala nanométrica. AgNPs apresentam atividades antimicrobianas contra fungos e bactérias; no entanto, a síntese de AgNPs pode gerar resíduos tóxicos e devido a isso novas rotas utilizando compostos atóxicos têm sido buscadas. O objetivo desse estudo foi sintetizar AgNPs utilizando a ribose como agente redutor e dodecil sulfato de sódio (SDS) como estabilizante e avaliar a atividade antifúngica dessas partículas contra C. albicans e C. tropicalis. Foram sintetizadas nanopartículas estáveis com 12,5 ± 0,2 nm (média ± DP) que apresentaram elevada atividade contra Candida spp. e podem representar boa alternativa no tratamento de infecções fúngicas. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2015-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/100972Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 No. 2 (2015); 165-167Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 Núm. 2 (2015); 165-167Revista do Instituto de Medicina Tropical de São Paulo; v. 57 n. 2 (2015); 165-1671678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/100972/99636Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessMALLMANN, Eduardo José J. CUNHA, Francisco Afrânio CASTRO, Bruno N.M.F. MACIEL, Auberson Martins MENEZES, Everardo Albuquerque FECHINE, Pierre Basílio Almeida 2015-07-28T11:57:31Zoai:revistas.usp.br:article/100972Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:30.850740Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Atividade antifúngica de nanopartículas de prata obtidas por síntese verde
ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS
title Atividade antifúngica de nanopartículas de prata obtidas por síntese verde
spellingShingle Atividade antifúngica de nanopartículas de prata obtidas por síntese verde
MALLMANN, Eduardo José J.
title_short Atividade antifúngica de nanopartículas de prata obtidas por síntese verde
title_full Atividade antifúngica de nanopartículas de prata obtidas por síntese verde
title_fullStr Atividade antifúngica de nanopartículas de prata obtidas por síntese verde
title_full_unstemmed Atividade antifúngica de nanopartículas de prata obtidas por síntese verde
title_sort Atividade antifúngica de nanopartículas de prata obtidas por síntese verde
author MALLMANN, Eduardo José J.
author_facet MALLMANN, Eduardo José J.
CUNHA, Francisco Afrânio
CASTRO, Bruno N.M.F.
MACIEL, Auberson Martins
MENEZES, Everardo Albuquerque
FECHINE, Pierre Basílio Almeida
author_role author
author2 CUNHA, Francisco Afrânio
CASTRO, Bruno N.M.F.
MACIEL, Auberson Martins
MENEZES, Everardo Albuquerque
FECHINE, Pierre Basílio Almeida
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv MALLMANN, Eduardo José J.
CUNHA, Francisco Afrânio
CASTRO, Bruno N.M.F.
MACIEL, Auberson Martins
MENEZES, Everardo Albuquerque
FECHINE, Pierre Basílio Almeida
description Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.
publishDate 2015
dc.date.none.fl_str_mv 2015-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/100972
url https://www.revistas.usp.br/rimtsp/article/view/100972
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/100972/99636
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 No. 2 (2015); 165-167
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 Núm. 2 (2015); 165-167
Revista do Instituto de Medicina Tropical de São Paulo; v. 57 n. 2 (2015); 165-167
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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