Alteração auditiva em pacientes com tuberculose no nordeste do Brasil

Detalhes bibliográficos
Autor(a) principal: Lima, Maria Luiza Lopes Timóteo de
Data de Publicação: 2006
Outros Autores: Lessa, Fábio, Aguiar-Santos, Ana Maria, Medeiros, Zulma
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/30980
Resumo: The aim of this paper is to describe the auditory profile of subjects who were given streptomycin treatment for tuberculosis in the years 2000 and 2001, in Recife, Northeast Brazil. The Injury Notification Database at the Municipal Department of Health was consulted and 78 individuals who had been on streptomycin during the period under study were selected. Forty-two individuals were excluded, of whom five were over 59 years of age and two were under 18 years. Nineteen turned out to be deceased, 13 could not be found, two were serving prison terms and one refused to participate. As a result, only 36 subjects participated in the study. These 36 individuals were interviewed and underwent meatoscopy and audiometry. The mean age of the group under study was 38.8 years old and males predominated (79.4%). Twenty-seven patients (75%) showed hearing impairment, the bilateral sensorineural type (63.9%) being the most frequent, mainly affecting the high frequencies over 4000 Hz. In the light of findings showing a high percentage of hearing impairment complaints among users of streptomycin, this issue seems to warrant an in-depth investigation, as does the implementation of an auditory follow-up routine for patients undergoing such chemotherapy for tuberculosis.
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spelling Alteração auditiva em pacientes com tuberculose no nordeste do Brasil Hearing impairment in patients with tuberculosis from Northeast Brazil TuberculosisHearing impairmentOtotoxicity The aim of this paper is to describe the auditory profile of subjects who were given streptomycin treatment for tuberculosis in the years 2000 and 2001, in Recife, Northeast Brazil. The Injury Notification Database at the Municipal Department of Health was consulted and 78 individuals who had been on streptomycin during the period under study were selected. Forty-two individuals were excluded, of whom five were over 59 years of age and two were under 18 years. Nineteen turned out to be deceased, 13 could not be found, two were serving prison terms and one refused to participate. As a result, only 36 subjects participated in the study. These 36 individuals were interviewed and underwent meatoscopy and audiometry. The mean age of the group under study was 38.8 years old and males predominated (79.4%). Twenty-seven patients (75%) showed hearing impairment, the bilateral sensorineural type (63.9%) being the most frequent, mainly affecting the high frequencies over 4000 Hz. In the light of findings showing a high percentage of hearing impairment complaints among users of streptomycin, this issue seems to warrant an in-depth investigation, as does the implementation of an auditory follow-up routine for patients undergoing such chemotherapy for tuberculosis. Este trabalho teve por objetivo descrever o perfil auditivo de pessoas que realizaram tratamento para tuberculose com estreptomicina em Recife nos anos de 2000 e 2001. Para tal foi utilizado o banco de dados do Sistema de Informação de Agravos de Notificação, fornecido pela Secretária de Saúde deste município, sendo selecionadas 78 pessoas que usaram a droga no período em estudo. Do total de pacientes selecionados sete eram menores de 18 anos ou maiores de 58 anos, 19 haviam falecido, 13 não foram localizados, dois eram presidiários, um negou-se a participar, restando, pois 36 indivíduos que puderam ser submetidos a uma entrevista, a meatoscopia e a audiometria. No grupo estudado predominou o sexo masculino (79,4%) e a média das idades era de 38,8 anos. Dos 36 pacientes, 27 (75,0%) apresentaram alteração auditiva, sendo a mais freqüente a sensório-neural bilateral (63,9%), com predomínio de freqüências agudas, a partir de 4000 Hz. Os achados com elevados percentuais de alteração auditiva entre os usuários de estreptomicina, apontam para a necessidade de aprofundamento deste tema em outros estudos, e também sugerem a necessidade de estruturação de um sistema de monitoramento auditivo para a população de pacientes submetidos a esse quimioterápico no tratamento para tuberculose. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2006-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/30980Revista do Instituto de Medicina Tropical de São Paulo; Vol. 48 No. 2 (2006); 99-102 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 48 Núm. 2 (2006); 99-102 Revista do Instituto de Medicina Tropical de São Paulo; v. 48 n. 2 (2006); 99-102 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/30980/32864Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessLima, Maria Luiza Lopes Timóteo deLessa, FábioAguiar-Santos, Ana MariaMedeiros, Zulma2012-07-07T18:52:35Zoai:revistas.usp.br:article/30980Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:41.834395Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
Hearing impairment in patients with tuberculosis from Northeast Brazil
title Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
spellingShingle Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
Lima, Maria Luiza Lopes Timóteo de
Tuberculosis
Hearing impairment
Ototoxicity
title_short Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
title_full Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
title_fullStr Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
title_full_unstemmed Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
title_sort Alteração auditiva em pacientes com tuberculose no nordeste do Brasil
author Lima, Maria Luiza Lopes Timóteo de
author_facet Lima, Maria Luiza Lopes Timóteo de
Lessa, Fábio
Aguiar-Santos, Ana Maria
Medeiros, Zulma
author_role author
author2 Lessa, Fábio
Aguiar-Santos, Ana Maria
Medeiros, Zulma
author2_role author
author
author
dc.contributor.author.fl_str_mv Lima, Maria Luiza Lopes Timóteo de
Lessa, Fábio
Aguiar-Santos, Ana Maria
Medeiros, Zulma
dc.subject.por.fl_str_mv Tuberculosis
Hearing impairment
Ototoxicity
topic Tuberculosis
Hearing impairment
Ototoxicity
description The aim of this paper is to describe the auditory profile of subjects who were given streptomycin treatment for tuberculosis in the years 2000 and 2001, in Recife, Northeast Brazil. The Injury Notification Database at the Municipal Department of Health was consulted and 78 individuals who had been on streptomycin during the period under study were selected. Forty-two individuals were excluded, of whom five were over 59 years of age and two were under 18 years. Nineteen turned out to be deceased, 13 could not be found, two were serving prison terms and one refused to participate. As a result, only 36 subjects participated in the study. These 36 individuals were interviewed and underwent meatoscopy and audiometry. The mean age of the group under study was 38.8 years old and males predominated (79.4%). Twenty-seven patients (75%) showed hearing impairment, the bilateral sensorineural type (63.9%) being the most frequent, mainly affecting the high frequencies over 4000 Hz. In the light of findings showing a high percentage of hearing impairment complaints among users of streptomycin, this issue seems to warrant an in-depth investigation, as does the implementation of an auditory follow-up routine for patients undergoing such chemotherapy for tuberculosis.
publishDate 2006
dc.date.none.fl_str_mv 2006-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/30980
url https://www.revistas.usp.br/rimtsp/article/view/30980
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/30980/32864
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 48 No. 2 (2006); 99-102
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 48 Núm. 2 (2006); 99-102
Revista do Instituto de Medicina Tropical de São Paulo; v. 48 n. 2 (2006); 99-102
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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