Pasteurization of human milk to prevent transmission of Chagas disease

Detalhes bibliográficos
Autor(a) principal: FERREIRA, Cláudio Santos
Data de Publicação: 2001
Outros Autores: MARTINHO, Prazeres Conceição, AMATO NETO, Vicente, CRUZ, Roseana Rodrigues Bressane
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/30513
Resumo: Although admittedly transmission of Trypanosoma cruzi infection through breastfeeding is a rare event, it involves serious risks. To test the effectiveness of pasteurization in preventing this mode of infection, three sets of samples of human milk were tested: a - contaminated with T. cruzi and pasteurized; b - contaminated with T. cruzi and non-pasteurized; c - non-contaminated and pasteurized. Samples from all sets were orally and intraperitoneally administered to 90 BALB/c mice. The animals inoculated with contaminated, non-pasteurized samples, got the infection. Controls and the animals inoculated with contaminated and pasteurized milk were not infected. The hypothesis was accepted that pasteurization inactivates T. cruzi trypomastigotes.
id IMT-1_651ed0d231d008cad009ae48f1410e03
oai_identifier_str oai:revistas.usp.br:article/30513
network_acronym_str IMT-1
network_name_str Revista do Instituto de Medicina Tropical de São Paulo
repository_id_str
spelling Pasteurization of human milk to prevent transmission of Chagas disease Pasteurização de leite humano para evitar a transmissão da doença de Chagas Trypanosoma cruziPasteurization of human milkMilk banks Although admittedly transmission of Trypanosoma cruzi infection through breastfeeding is a rare event, it involves serious risks. To test the effectiveness of pasteurization in preventing this mode of infection, three sets of samples of human milk were tested: a - contaminated with T. cruzi and pasteurized; b - contaminated with T. cruzi and non-pasteurized; c - non-contaminated and pasteurized. Samples from all sets were orally and intraperitoneally administered to 90 BALB/c mice. The animals inoculated with contaminated, non-pasteurized samples, got the infection. Controls and the animals inoculated with contaminated and pasteurized milk were not infected. The hypothesis was accepted that pasteurization inactivates T. cruzi trypomastigotes. A amamentação é modo alternativo de transmitir-se a doença de Chagas. Embora admitida como evento raro, a infecção por esta via é preocupante. Para evitá-la é sugerida a pasteurização. Separaram-se para o ensaio três conjuntos de amostras de leite humano: a - contaminadas por Trypanosoma cruzi e pasteurizadas; b - contaminadas por T. cruzi e não pasteurizadas; c - não contaminadas e pasteurizadas. Frações dos três conjuntos foram inoculadas por vias oral e intraperitoneal em 90 camundongos BALB/c. Os animais inoculados com leite contaminado e não pasteurizado infectaram-se. Os controles e os inoculados com leite contaminado e pasteurizado não se infectaram. Aceitou-se a hipótese de a pasteurização ter inativado as formas tripomastigotas de T. cruzi em suspensão no leite. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2001-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/30513Revista do Instituto de Medicina Tropical de São Paulo; Vol. 43 No. 3 (2001); 161-162 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 43 Núm. 3 (2001); 161-162 Revista do Instituto de Medicina Tropical de São Paulo; v. 43 n. 3 (2001); 161-162 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/30513/32397Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessFERREIRA, Cláudio SantosMARTINHO, Prazeres ConceiçãoAMATO NETO, VicenteCRUZ, Roseana Rodrigues Bressane2012-07-07T13:33:51Zoai:revistas.usp.br:article/30513Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:17.882421Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Pasteurization of human milk to prevent transmission of Chagas disease
Pasteurização de leite humano para evitar a transmissão da doença de Chagas
title Pasteurization of human milk to prevent transmission of Chagas disease
spellingShingle Pasteurization of human milk to prevent transmission of Chagas disease
FERREIRA, Cláudio Santos
Trypanosoma cruzi
Pasteurization of human milk
Milk banks
title_short Pasteurization of human milk to prevent transmission of Chagas disease
title_full Pasteurization of human milk to prevent transmission of Chagas disease
title_fullStr Pasteurization of human milk to prevent transmission of Chagas disease
title_full_unstemmed Pasteurization of human milk to prevent transmission of Chagas disease
title_sort Pasteurization of human milk to prevent transmission of Chagas disease
author FERREIRA, Cláudio Santos
author_facet FERREIRA, Cláudio Santos
MARTINHO, Prazeres Conceição
AMATO NETO, Vicente
CRUZ, Roseana Rodrigues Bressane
author_role author
author2 MARTINHO, Prazeres Conceição
AMATO NETO, Vicente
CRUZ, Roseana Rodrigues Bressane
author2_role author
author
author
dc.contributor.author.fl_str_mv FERREIRA, Cláudio Santos
MARTINHO, Prazeres Conceição
AMATO NETO, Vicente
CRUZ, Roseana Rodrigues Bressane
dc.subject.por.fl_str_mv Trypanosoma cruzi
Pasteurization of human milk
Milk banks
topic Trypanosoma cruzi
Pasteurization of human milk
Milk banks
description Although admittedly transmission of Trypanosoma cruzi infection through breastfeeding is a rare event, it involves serious risks. To test the effectiveness of pasteurization in preventing this mode of infection, three sets of samples of human milk were tested: a - contaminated with T. cruzi and pasteurized; b - contaminated with T. cruzi and non-pasteurized; c - non-contaminated and pasteurized. Samples from all sets were orally and intraperitoneally administered to 90 BALB/c mice. The animals inoculated with contaminated, non-pasteurized samples, got the infection. Controls and the animals inoculated with contaminated and pasteurized milk were not infected. The hypothesis was accepted that pasteurization inactivates T. cruzi trypomastigotes.
publishDate 2001
dc.date.none.fl_str_mv 2001-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/30513
url https://www.revistas.usp.br/rimtsp/article/view/30513
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/30513/32397
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 43 No. 3 (2001); 161-162
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 43 Núm. 3 (2001); 161-162
Revista do Instituto de Medicina Tropical de São Paulo; v. 43 n. 3 (2001); 161-162
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
_version_ 1798951642916192256

Registros relacionados