Suspected vertical transmission of Chagas disease caused by DTU TcIV in an infection probably transmitted orally, during anoutbreak in the Brazilian Amazo

• Autor(a) principal: Freitas , Vera Lúcia Teixeira de
• Data de Publicação: 2021
• Outros Autores: Esper , Helena Rangel, Nakanishi, Erika Shimoda, Piotto, Mariana Ramos, Assy, João Guilherme Pontes Lima, Berreta , Olívia Campos Pinheiro Berreta, Said, Renato do Carmo, Segurado , Aluisio Augusto Cotrim Segurado, Carvalho, Noemia Barbosa Carvalho, França, Francisco Oscar de Siqueira, Lopes , Marta Heloísa
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
• Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/188979
• topic: Acute Chagas disease; Child. Diagnosis; Trypanosoma cruzi; DTUs; Vertical transmission; Oral outbreak

This study describes difficulties in the monitoring of a child born during an oral outbreak of Chagas disease, in which there are several indications that the transmission occurred through the congenital route: 1. the mother was in the third trimester of pregnancy when she was infected; 2. She presented high parasitemia at the time of delivery; 3. In both, the mother and her daughter, T. cruzi was classified as DTU TcIV. The parasites were not found in the blood at birth and the infection was detected only three months later in an asymptomatic infant. As the mother and her child live in a highly endemic area, vector transmission could not be excluded during this period.