Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis

Detalhes bibliográficos
Autor(a) principal: Rossi, Cláudio L.
Data de Publicação: 1993
Outros Autores: Takahashi, Emilia E. H., Partel, Cláudia D., Teodoro, Lívia G.V.L., Silva, Luiz J. da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/29059
Resumo: Total serum IgE, and Strongyloides - specific IgG and IgA antibodies were studied in 27 patients with parasitologically proven strongyloidiasis. Clinical manifestations in this case series were investigated by a restrospective study of the patient's records. Total serum IgE levels were elevated (greater than 250 IU/ml) in 59% of the patients (mean concentration = 1364 IU/ml). Parasite - specific IgG and IgA antibodies were detected by ELISA in the serum of 23 (85.2%) and 21 (77.8%) patients, respectively. Elevated serum IgE and clinical manifestations were not useful indexes of the presence of strongyloidiasis. On the other hand, our results support the view that serologic tests, particularly ELISA for detecting Strongyloides - specific IgG antibodies, can be usefully exploited for diagnostic purposes in strongyloidiasis.
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spelling Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis IgE sérica total e anticorpos IgG e IgA anti: S. stercoralis na estrongiloidíase humana Strongyloides stercoralisStrongyloidiasisImmunodiagnosis Total serum IgE, and Strongyloides - specific IgG and IgA antibodies were studied in 27 patients with parasitologically proven strongyloidiasis. Clinical manifestations in this case series were investigated by a restrospective study of the patient's records. Total serum IgE levels were elevated (greater than 250 IU/ml) in 59% of the patients (mean concentration = 1364 IU/ml). Parasite - specific IgG and IgA antibodies were detected by ELISA in the serum of 23 (85.2%) and 21 (77.8%) patients, respectively. Elevated serum IgE and clinical manifestations were not useful indexes of the presence of strongyloidiasis. On the other hand, our results support the view that serologic tests, particularly ELISA for detecting Strongyloides - specific IgG antibodies, can be usefully exploited for diagnostic purposes in strongyloidiasis. Níveis de IgE sérica total e anticorpos específicos IgG e IgA anti - Strongyloides stercoralis foram pesquisados, através de técnicas imunoenzimáticas, em 27 pacientes com estrongiloidíase comprovada por métodos parasitológicos. Manifestações clínicas nesta série de casos foram investigadas pelo estudo retrospectivo dos prontuarios dos pacientes. Os níveis de IgE sérica foram elevados (maior do que 250 UI/ml) em 59% dos pacientes (concentração média = 1364 UI/ml). Anticorpos específicos IgG e IgA anti - S. stercoralis foram detectados, respectivamente, em 23 (85.2%) e 21 (77.8%) pacientes. No presente estudo, níveis elevados de IgE sérica e manifestações clínicas apresentadas pelos pacientes não contribuíram significativamente para o diagnóstico de estrongiloidíase. Por outro lado, os resultados deste trabalho corroboram o ponto de vista que as técnicas sorológicas para a detecção de anticorpos específicos anti-S. stercoralis, particularmente as técnicas imunoenzimáticas para a detecção de anticorpos específicos da classe IgG, podem ser de grande utilidade para o diagnóstico da estrongiloidíase. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1993-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/29059Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 No. 4 (1993); 361-365 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 Núm. 4 (1993); 361-365 Revista do Instituto de Medicina Tropical de São Paulo; v. 35 n. 4 (1993); 361-365 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/29059/30916Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessRossi, Cláudio L.Takahashi, Emilia E. H.Partel, Cláudia D.Teodoro, Lívia G.V.L.Silva, Luiz J. da2012-07-02T01:35:50Zoai:revistas.usp.br:article/29059Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:50:49.104100Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
IgE sérica total e anticorpos IgG e IgA anti: S. stercoralis na estrongiloidíase humana
title Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
spellingShingle Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
Rossi, Cláudio L.
Strongyloides stercoralis
Strongyloidiasis
Immunodiagnosis
title_short Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
title_full Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
title_fullStr Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
title_full_unstemmed Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
title_sort Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
author Rossi, Cláudio L.
author_facet Rossi, Cláudio L.
Takahashi, Emilia E. H.
Partel, Cláudia D.
Teodoro, Lívia G.V.L.
Silva, Luiz J. da
author_role author
author2 Takahashi, Emilia E. H.
Partel, Cláudia D.
Teodoro, Lívia G.V.L.
Silva, Luiz J. da
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Rossi, Cláudio L.
Takahashi, Emilia E. H.
Partel, Cláudia D.
Teodoro, Lívia G.V.L.
Silva, Luiz J. da
dc.subject.por.fl_str_mv Strongyloides stercoralis
Strongyloidiasis
Immunodiagnosis
topic Strongyloides stercoralis
Strongyloidiasis
Immunodiagnosis
description Total serum IgE, and Strongyloides - specific IgG and IgA antibodies were studied in 27 patients with parasitologically proven strongyloidiasis. Clinical manifestations in this case series were investigated by a restrospective study of the patient's records. Total serum IgE levels were elevated (greater than 250 IU/ml) in 59% of the patients (mean concentration = 1364 IU/ml). Parasite - specific IgG and IgA antibodies were detected by ELISA in the serum of 23 (85.2%) and 21 (77.8%) patients, respectively. Elevated serum IgE and clinical manifestations were not useful indexes of the presence of strongyloidiasis. On the other hand, our results support the view that serologic tests, particularly ELISA for detecting Strongyloides - specific IgG antibodies, can be usefully exploited for diagnostic purposes in strongyloidiasis.
publishDate 1993
dc.date.none.fl_str_mv 1993-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29059
url https://www.revistas.usp.br/rimtsp/article/view/29059
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29059/30916
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 No. 4 (1993); 361-365
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 Núm. 4 (1993); 361-365
Revista do Instituto de Medicina Tropical de São Paulo; v. 35 n. 4 (1993); 361-365
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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