Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis
Autor(a) principal: | |
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Data de Publicação: | 1993 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/29059 |
Resumo: | Total serum IgE, and Strongyloides - specific IgG and IgA antibodies were studied in 27 patients with parasitologically proven strongyloidiasis. Clinical manifestations in this case series were investigated by a restrospective study of the patient's records. Total serum IgE levels were elevated (greater than 250 IU/ml) in 59% of the patients (mean concentration = 1364 IU/ml). Parasite - specific IgG and IgA antibodies were detected by ELISA in the serum of 23 (85.2%) and 21 (77.8%) patients, respectively. Elevated serum IgE and clinical manifestations were not useful indexes of the presence of strongyloidiasis. On the other hand, our results support the view that serologic tests, particularly ELISA for detecting Strongyloides - specific IgG antibodies, can be usefully exploited for diagnostic purposes in strongyloidiasis. |
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Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis IgE sérica total e anticorpos IgG e IgA anti: S. stercoralis na estrongiloidíase humana Strongyloides stercoralisStrongyloidiasisImmunodiagnosis Total serum IgE, and Strongyloides - specific IgG and IgA antibodies were studied in 27 patients with parasitologically proven strongyloidiasis. Clinical manifestations in this case series were investigated by a restrospective study of the patient's records. Total serum IgE levels were elevated (greater than 250 IU/ml) in 59% of the patients (mean concentration = 1364 IU/ml). Parasite - specific IgG and IgA antibodies were detected by ELISA in the serum of 23 (85.2%) and 21 (77.8%) patients, respectively. Elevated serum IgE and clinical manifestations were not useful indexes of the presence of strongyloidiasis. On the other hand, our results support the view that serologic tests, particularly ELISA for detecting Strongyloides - specific IgG antibodies, can be usefully exploited for diagnostic purposes in strongyloidiasis. Níveis de IgE sérica total e anticorpos específicos IgG e IgA anti - Strongyloides stercoralis foram pesquisados, através de técnicas imunoenzimáticas, em 27 pacientes com estrongiloidíase comprovada por métodos parasitológicos. Manifestações clínicas nesta série de casos foram investigadas pelo estudo retrospectivo dos prontuarios dos pacientes. Os níveis de IgE sérica foram elevados (maior do que 250 UI/ml) em 59% dos pacientes (concentração média = 1364 UI/ml). Anticorpos específicos IgG e IgA anti - S. stercoralis foram detectados, respectivamente, em 23 (85.2%) e 21 (77.8%) pacientes. No presente estudo, níveis elevados de IgE sérica e manifestações clínicas apresentadas pelos pacientes não contribuíram significativamente para o diagnóstico de estrongiloidíase. Por outro lado, os resultados deste trabalho corroboram o ponto de vista que as técnicas sorológicas para a detecção de anticorpos específicos anti-S. stercoralis, particularmente as técnicas imunoenzimáticas para a detecção de anticorpos específicos da classe IgG, podem ser de grande utilidade para o diagnóstico da estrongiloidíase. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1993-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/29059Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 No. 4 (1993); 361-365 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 Núm. 4 (1993); 361-365 Revista do Instituto de Medicina Tropical de São Paulo; v. 35 n. 4 (1993); 361-365 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/29059/30916Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessRossi, Cláudio L.Takahashi, Emilia E. H.Partel, Cláudia D.Teodoro, Lívia G.V.L.Silva, Luiz J. da2012-07-02T01:35:50Zoai:revistas.usp.br:article/29059Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:50:49.104100Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis IgE sérica total e anticorpos IgG e IgA anti: S. stercoralis na estrongiloidíase humana |
title |
Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis |
spellingShingle |
Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis Rossi, Cláudio L. Strongyloides stercoralis Strongyloidiasis Immunodiagnosis |
title_short |
Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis |
title_full |
Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis |
title_fullStr |
Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis |
title_full_unstemmed |
Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis |
title_sort |
Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis |
author |
Rossi, Cláudio L. |
author_facet |
Rossi, Cláudio L. Takahashi, Emilia E. H. Partel, Cláudia D. Teodoro, Lívia G.V.L. Silva, Luiz J. da |
author_role |
author |
author2 |
Takahashi, Emilia E. H. Partel, Cláudia D. Teodoro, Lívia G.V.L. Silva, Luiz J. da |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Rossi, Cláudio L. Takahashi, Emilia E. H. Partel, Cláudia D. Teodoro, Lívia G.V.L. Silva, Luiz J. da |
dc.subject.por.fl_str_mv |
Strongyloides stercoralis Strongyloidiasis Immunodiagnosis |
topic |
Strongyloides stercoralis Strongyloidiasis Immunodiagnosis |
description |
Total serum IgE, and Strongyloides - specific IgG and IgA antibodies were studied in 27 patients with parasitologically proven strongyloidiasis. Clinical manifestations in this case series were investigated by a restrospective study of the patient's records. Total serum IgE levels were elevated (greater than 250 IU/ml) in 59% of the patients (mean concentration = 1364 IU/ml). Parasite - specific IgG and IgA antibodies were detected by ELISA in the serum of 23 (85.2%) and 21 (77.8%) patients, respectively. Elevated serum IgE and clinical manifestations were not useful indexes of the presence of strongyloidiasis. On the other hand, our results support the view that serologic tests, particularly ELISA for detecting Strongyloides - specific IgG antibodies, can be usefully exploited for diagnostic purposes in strongyloidiasis. |
publishDate |
1993 |
dc.date.none.fl_str_mv |
1993-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/29059 |
url |
https://www.revistas.usp.br/rimtsp/article/view/29059 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/29059/30916 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 No. 4 (1993); 361-365 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 Núm. 4 (1993); 361-365 Revista do Instituto de Medicina Tropical de São Paulo; v. 35 n. 4 (1993); 361-365 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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1798951640493981696 |