Evaluation of the resistance to Schistosoma mansoni infection in Nectomys squamipes (Rodentia: Cricetidae), a natural host of infection in Brazil

Detalhes bibliográficos
Autor(a) principal: Maldonado Jr., Arnaldo
Data de Publicação: 1994
Outros Autores: Machado e Silva, José Roberto, Rodrigues e Silva, Rosângela, Lenzi, Henrique Leonel, Rey, Luis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/29153
Resumo: The development of resistance in three stages throughout an active infection (pre-ovular, acute and initial chronic stages) was studied, comparing the total number of adult worms recovered from the reinfected group and the control groups. It was shown that Nectomys squamipes was unable to develop resistance in the tested conditions and, on the other hand, reinfection in the pre-ovular period of the parasite led the rodent to present the phenomenonacilitation, with reduction of natural resistance and an increase in the parasite load. These results suggest the existence of other forms of immunity diverse from the concomitant immunity in the host-parasite relationship, according to the employed model.
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spelling Evaluation of the resistance to Schistosoma mansoni infection in Nectomys squamipes (Rodentia: Cricetidae), a natural host of infection in Brazil Avaliação da resistencia na infecção por Schistosoma mansoni em Nectomys squamipes (Rodentia: Cricetidae) um hospedeiro natural da infecção no Brasil Nectomys squamipesReinfectionImmunityWild rodentExperimental schistosomiasisSchistosoma mansoni The development of resistance in three stages throughout an active infection (pre-ovular, acute and initial chronic stages) was studied, comparing the total number of adult worms recovered from the reinfected group and the control groups. It was shown that Nectomys squamipes was unable to develop resistance in the tested conditions and, on the other hand, reinfection in the pre-ovular period of the parasite led the rodent to present the phenomenonacilitation, with reduction of natural resistance and an increase in the parasite load. These results suggest the existence of other forms of immunity diverse from the concomitant immunity in the host-parasite relationship, according to the employed model. O desenvolvimento de resistência em três fases do transcurso de uma infecção ativa (fase pré-ovular, aguda e crônica inicial) foi estudada comparando-se o número total de vermes adultos recuperados no grupo reinfectado e o somatório dos grupos controles. Demonstrou-se que o N. squamipes não foi capaz de desenvolver resistência nas condições testadas e que ao contrário, a reinfecção no período pré-ovular do parasito levou o roedor a apresentar o fenômeno de facilitação, com redução da resistência natural e aumento da carga parasitária. Esses resultados sugerem a existência de outras formas de imunidade, distintas da imunidade concomitante, segundo o modelo empregado. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1994-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/29153Revista do Instituto de Medicina Tropical de São Paulo; Vol. 36 No. 3 (1994); 193-198 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 36 Núm. 3 (1994); 193-198 Revista do Instituto de Medicina Tropical de São Paulo; v. 36 n. 3 (1994); 193-198 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/29153/31010Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessMaldonado Jr., ArnaldoMachado e Silva, José RobertoRodrigues e Silva, RosângelaLenzi, Henrique LeonelRey, Luis2012-07-02T01:37:35Zoai:revistas.usp.br:article/29153Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:50:54.329070Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Evaluation of the resistance to Schistosoma mansoni infection in Nectomys squamipes (Rodentia: Cricetidae), a natural host of infection in Brazil
Avaliação da resistencia na infecção por Schistosoma mansoni em Nectomys squamipes (Rodentia: Cricetidae) um hospedeiro natural da infecção no Brasil
title Evaluation of the resistance to Schistosoma mansoni infection in Nectomys squamipes (Rodentia: Cricetidae), a natural host of infection in Brazil
spellingShingle Evaluation of the resistance to Schistosoma mansoni infection in Nectomys squamipes (Rodentia: Cricetidae), a natural host of infection in Brazil
Maldonado Jr., Arnaldo
Nectomys squamipes
Reinfection
Immunity
Wild rodent
Experimental schistosomiasis
Schistosoma mansoni
title_short Evaluation of the resistance to Schistosoma mansoni infection in Nectomys squamipes (Rodentia: Cricetidae), a natural host of infection in Brazil
title_full Evaluation of the resistance to Schistosoma mansoni infection in Nectomys squamipes (Rodentia: Cricetidae), a natural host of infection in Brazil
title_fullStr Evaluation of the resistance to Schistosoma mansoni infection in Nectomys squamipes (Rodentia: Cricetidae), a natural host of infection in Brazil
title_full_unstemmed Evaluation of the resistance to Schistosoma mansoni infection in Nectomys squamipes (Rodentia: Cricetidae), a natural host of infection in Brazil
title_sort Evaluation of the resistance to Schistosoma mansoni infection in Nectomys squamipes (Rodentia: Cricetidae), a natural host of infection in Brazil
author Maldonado Jr., Arnaldo
author_facet Maldonado Jr., Arnaldo
Machado e Silva, José Roberto
Rodrigues e Silva, Rosângela
Lenzi, Henrique Leonel
Rey, Luis
author_role author
author2 Machado e Silva, José Roberto
Rodrigues e Silva, Rosângela
Lenzi, Henrique Leonel
Rey, Luis
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Maldonado Jr., Arnaldo
Machado e Silva, José Roberto
Rodrigues e Silva, Rosângela
Lenzi, Henrique Leonel
Rey, Luis
dc.subject.por.fl_str_mv Nectomys squamipes
Reinfection
Immunity
Wild rodent
Experimental schistosomiasis
Schistosoma mansoni
topic Nectomys squamipes
Reinfection
Immunity
Wild rodent
Experimental schistosomiasis
Schistosoma mansoni
description The development of resistance in three stages throughout an active infection (pre-ovular, acute and initial chronic stages) was studied, comparing the total number of adult worms recovered from the reinfected group and the control groups. It was shown that Nectomys squamipes was unable to develop resistance in the tested conditions and, on the other hand, reinfection in the pre-ovular period of the parasite led the rodent to present the phenomenonacilitation, with reduction of natural resistance and an increase in the parasite load. These results suggest the existence of other forms of immunity diverse from the concomitant immunity in the host-parasite relationship, according to the employed model.
publishDate 1994
dc.date.none.fl_str_mv 1994-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29153
url https://www.revistas.usp.br/rimtsp/article/view/29153
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29153/31010
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 36 No. 3 (1994); 193-198
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 36 Núm. 3 (1994); 193-198
Revista do Instituto de Medicina Tropical de São Paulo; v. 36 n. 3 (1994); 193-198
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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