The circumovat precipitin test as a control of cure in children with chronic schistosomiasis mansoni
Autor(a) principal: | |
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Data de Publicação: | 1983 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/196336 |
Resumo: | Seventy nine children in the 6-14 age group, with chronic schistosomiasis man- soni were selected for this stud,y. Sixty seven (850/o) with positive circumoval pre- cipitin test (COPT) were divided in two groups: 86 children (Group l) were treat_ ed with oxamniquine (20 mg/kg in a singre orar dose) and 31 children (Group 2) were given placebo under the same conditions. Follow-up was mantained for 1.0 months with monthly quantitative stool examinations and the absence of fecal eggs from the first month onwards was considered as a successful treatment. COPT was repeated on the tenth month. In Group L, 6gVo were cured. Group P showed no cures. rn the 28 Group I patients considered cured, copr was negative in20 (87%). Negative reactions were also found in BZo/o of the Group p children, after 10 months. These false negative reactions occurred in patients with a smaller stool egg count. The Authors conclude that copr shows a high positivity ratio in the diagnosis of chronic schistosomiasis mansoni, with negative reactions post cure in the majority of cases. However, a significant number of false negative results does rlot allow the isolated use of COPT in the control of cure of schistosomiasis mansoni. |
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The circumovat precipitin test as a control of cure in children with chronic schistosomiasis mansoniSeventy nine children in the 6-14 age group, with chronic schistosomiasis man- soni were selected for this stud,y. Sixty seven (850/o) with positive circumoval pre- cipitin test (COPT) were divided in two groups: 86 children (Group l) were treat_ ed with oxamniquine (20 mg/kg in a singre orar dose) and 31 children (Group 2) were given placebo under the same conditions. Follow-up was mantained for 1.0 months with monthly quantitative stool examinations and the absence of fecal eggs from the first month onwards was considered as a successful treatment. COPT was repeated on the tenth month. In Group L, 6gVo were cured. Group P showed no cures. rn the 28 Group I patients considered cured, copr was negative in20 (87%). Negative reactions were also found in BZo/o of the Group p children, after 10 months. These false negative reactions occurred in patients with a smaller stool egg count. The Authors conclude that copr shows a high positivity ratio in the diagnosis of chronic schistosomiasis mansoni, with negative reactions post cure in the majority of cases. However, a significant number of false negative results does rlot allow the isolated use of COPT in the control of cure of schistosomiasis mansoni.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1983-04-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/196336Revista do Instituto de Medicina Tropical de São Paulo; Vol. 25 No. 1 (1983); 37-41Revista do Instituto de Medicina Tropical de São Paulo; Vol. 25 Núm. 1 (1983); 37-41Revista do Instituto de Medicina Tropical de São Paulo; v. 25 n. 1 (1983); 37-411678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/196336/180969Copyright (c) 2022 José Roberto Lambertucci, Rômulo Teixeira de Mello, Énio Roberto Pietra Pedroso, Dirceu B. Greco, Manoel O. C. Rochahttps://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessLambertucci, José Roberto Mello, Rômulo Teixeira de Pedroso, Énio Roberto Pietra Greco, Dirceu B. Rocha, Manoel O. C. 2022-04-05T17:00:36Zoai:revistas.usp.br:article/196336Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:53:02.824248Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
The circumovat precipitin test as a control of cure in children with chronic schistosomiasis mansoni |
title |
The circumovat precipitin test as a control of cure in children with chronic schistosomiasis mansoni |
spellingShingle |
The circumovat precipitin test as a control of cure in children with chronic schistosomiasis mansoni Lambertucci, José Roberto |
title_short |
The circumovat precipitin test as a control of cure in children with chronic schistosomiasis mansoni |
title_full |
The circumovat precipitin test as a control of cure in children with chronic schistosomiasis mansoni |
title_fullStr |
The circumovat precipitin test as a control of cure in children with chronic schistosomiasis mansoni |
title_full_unstemmed |
The circumovat precipitin test as a control of cure in children with chronic schistosomiasis mansoni |
title_sort |
The circumovat precipitin test as a control of cure in children with chronic schistosomiasis mansoni |
author |
Lambertucci, José Roberto |
author_facet |
Lambertucci, José Roberto Mello, Rômulo Teixeira de Pedroso, Énio Roberto Pietra Greco, Dirceu B. Rocha, Manoel O. C. |
author_role |
author |
author2 |
Mello, Rômulo Teixeira de Pedroso, Énio Roberto Pietra Greco, Dirceu B. Rocha, Manoel O. C. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Lambertucci, José Roberto Mello, Rômulo Teixeira de Pedroso, Énio Roberto Pietra Greco, Dirceu B. Rocha, Manoel O. C. |
description |
Seventy nine children in the 6-14 age group, with chronic schistosomiasis man- soni were selected for this stud,y. Sixty seven (850/o) with positive circumoval pre- cipitin test (COPT) were divided in two groups: 86 children (Group l) were treat_ ed with oxamniquine (20 mg/kg in a singre orar dose) and 31 children (Group 2) were given placebo under the same conditions. Follow-up was mantained for 1.0 months with monthly quantitative stool examinations and the absence of fecal eggs from the first month onwards was considered as a successful treatment. COPT was repeated on the tenth month. In Group L, 6gVo were cured. Group P showed no cures. rn the 28 Group I patients considered cured, copr was negative in20 (87%). Negative reactions were also found in BZo/o of the Group p children, after 10 months. These false negative reactions occurred in patients with a smaller stool egg count. The Authors conclude that copr shows a high positivity ratio in the diagnosis of chronic schistosomiasis mansoni, with negative reactions post cure in the majority of cases. However, a significant number of false negative results does rlot allow the isolated use of COPT in the control of cure of schistosomiasis mansoni. |
publishDate |
1983 |
dc.date.none.fl_str_mv |
1983-04-05 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/196336 |
url |
https://www.revistas.usp.br/rimtsp/article/view/196336 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/196336/180969 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 25 No. 1 (1983); 37-41 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 25 Núm. 1 (1983); 37-41 Revista do Instituto de Medicina Tropical de São Paulo; v. 25 n. 1 (1983); 37-41 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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1798951653792022528 |