Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?

Detalhes bibliográficos
Autor(a) principal: Santos, Ana Carolina Etrusco Zaroni
Data de Publicação: 2020
Outros Autores: Sztajnbok, Jaques, Duarte-Neto, Amaro Nunes, Sousa , Amanda Freire Tamburini, Lopes, Alessandra Geisler Daud, Barrientos, Anna Carlota Mott
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/176687
Resumo: Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to disseminated tuberculosis with extensive intestinal involvement characterized by massive intestinal bleeding and hemorrhagic shock. The severity of the intestinal involvement precluded the exclusive use of oral anti-tuberculosis drugs and the patient was successfully treated with a combination of injectable and oral anti-tuberculosis agents. We discuss the importance of a regimen with injectable drugs for treating severe forms of tuberculosis in which the intestinal involvement impaired the use of oral drugs.
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spelling Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?Gastrintestinal tuberculosisBleedingPediatricInjectable antituberculous drugsDisseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to disseminated tuberculosis with extensive intestinal involvement characterized by massive intestinal bleeding and hemorrhagic shock. The severity of the intestinal involvement precluded the exclusive use of oral anti-tuberculosis drugs and the patient was successfully treated with a combination of injectable and oral anti-tuberculosis agents. We discuss the importance of a regimen with injectable drugs for treating severe forms of tuberculosis in which the intestinal involvement impaired the use of oral drugs.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2020-10-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/xmlhttps://www.revistas.usp.br/rimtsp/article/view/17668710.1590/S1678-9946202062078Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e78Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e78Revista do Instituto de Medicina Tropical de São Paulo; v. 62 (2020); e781678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/176687/164039https://www.revistas.usp.br/rimtsp/article/view/176687/164040Copyright (c) 2020 Revista do Instituto de Medicina Tropical de São Paulohttp://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessSantos, Ana Carolina Etrusco Zaroni Sztajnbok, Jaques Duarte-Neto, Amaro Nunes Sousa , Amanda Freire Tamburini Lopes, Alessandra Geisler Daud Barrientos, Anna Carlota Mott 2020-10-26T17:39:25Zoai:revistas.usp.br:article/176687Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:53.725541Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?
title Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?
spellingShingle Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?
Santos, Ana Carolina Etrusco Zaroni
Gastrintestinal tuberculosis
Bleeding
Pediatric
Injectable antituberculous drugs
title_short Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?
title_full Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?
title_fullStr Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?
title_full_unstemmed Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?
title_sort Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?
author Santos, Ana Carolina Etrusco Zaroni
author_facet Santos, Ana Carolina Etrusco Zaroni
Sztajnbok, Jaques
Duarte-Neto, Amaro Nunes
Sousa , Amanda Freire Tamburini
Lopes, Alessandra Geisler Daud
Barrientos, Anna Carlota Mott
author_role author
author2 Sztajnbok, Jaques
Duarte-Neto, Amaro Nunes
Sousa , Amanda Freire Tamburini
Lopes, Alessandra Geisler Daud
Barrientos, Anna Carlota Mott
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Santos, Ana Carolina Etrusco Zaroni
Sztajnbok, Jaques
Duarte-Neto, Amaro Nunes
Sousa , Amanda Freire Tamburini
Lopes, Alessandra Geisler Daud
Barrientos, Anna Carlota Mott
dc.subject.por.fl_str_mv Gastrintestinal tuberculosis
Bleeding
Pediatric
Injectable antituberculous drugs
topic Gastrintestinal tuberculosis
Bleeding
Pediatric
Injectable antituberculous drugs
description Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to disseminated tuberculosis with extensive intestinal involvement characterized by massive intestinal bleeding and hemorrhagic shock. The severity of the intestinal involvement precluded the exclusive use of oral anti-tuberculosis drugs and the patient was successfully treated with a combination of injectable and oral anti-tuberculosis agents. We discuss the importance of a regimen with injectable drugs for treating severe forms of tuberculosis in which the intestinal involvement impaired the use of oral drugs.
publishDate 2020
dc.date.none.fl_str_mv 2020-10-26
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/176687
10.1590/S1678-9946202062078
url https://www.revistas.usp.br/rimtsp/article/view/176687
identifier_str_mv 10.1590/S1678-9946202062078
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/176687/164039
https://www.revistas.usp.br/rimtsp/article/view/176687/164040
dc.rights.driver.fl_str_mv Copyright (c) 2020 Revista do Instituto de Medicina Tropical de São Paulo
http://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Revista do Instituto de Medicina Tropical de São Paulo
http://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/xml
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e78
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e78
Revista do Instituto de Medicina Tropical de São Paulo; v. 62 (2020); e78
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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