Infecção por citomegalovírus em creche do município de São Paulo
Autor(a) principal: | |
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Data de Publicação: | 1996 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/29356 |
Resumo: | The prevalence of antibodies against cytomegalovirus (CMV) and the incidence of CMV infection were tested in 98 children aged 5 to 36 months who attended the day-care center of a University hospital in São Paulo. At the beginning of the study the overall prevalence of anti-CMV IgG antibodies was 44% (43/98). Saliva and/or urine samples were obtained from 38 of the 43 children that were seropositive at the beginning of the study for isolation of the virus, and 52.6% of these children were found to excrete CMV in one of the two materials. Among the 37 children that were initially seronegative from whom it was possible to obtain a new blood sample 6 to 12 months later, 22 (59.5%) presented seroconversion. The rate of viral excretion through urine or saliva from the children that seroconverted was 50%. These results indicate that CMV infection is frequent and occurs early among the children who attend this day-care center. However, controlled studies using molecular epidemiology techniques are needed to define more precisely the role of day-care centers in CMV dissemination. |
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Infecção por citomegalovírus em creche do município de São Paulo Cytomegalovirus infection in a day-care center in the municipality of São Paulo CytomegalovirusDay-Care centerEpidemiology The prevalence of antibodies against cytomegalovirus (CMV) and the incidence of CMV infection were tested in 98 children aged 5 to 36 months who attended the day-care center of a University hospital in São Paulo. At the beginning of the study the overall prevalence of anti-CMV IgG antibodies was 44% (43/98). Saliva and/or urine samples were obtained from 38 of the 43 children that were seropositive at the beginning of the study for isolation of the virus, and 52.6% of these children were found to excrete CMV in one of the two materials. Among the 37 children that were initially seronegative from whom it was possible to obtain a new blood sample 6 to 12 months later, 22 (59.5%) presented seroconversion. The rate of viral excretion through urine or saliva from the children that seroconverted was 50%. These results indicate that CMV infection is frequent and occurs early among the children who attend this day-care center. However, controlled studies using molecular epidemiology techniques are needed to define more precisely the role of day-care centers in CMV dissemination. A prevalência de anticorpos e a incidência de infecção por citomegalovírus (CMV) foram estudadas em 98 crianças de 5 a 36 meses de idade que freqüentavam a creche de um hospital universitário em São Paulo. No início do estudo, a prevalência geral de anticorpos para o CMV foi de 44% (43/98). Obteve-se para o isolamento viral, amostras de saliva e/ou urina de 36 das 43 crianças que eram soropositivas, constatando-se que 55,6% das mesmas estavam excretando CMV em um dos materiais. Das 37 crianças inicialmente soronegativas, das quais foi possível obter nova amostra de sangue 6 a 12 meses após, 22 (59,5%) apresentaram soroconversão. A taxa de excreção viral na urina ou saliva nas crianças que soroconverteram foi de 52,4%. Estes resultados indicam que a infecção por CMV foi freqüente e ocorreu precocemente nas crianças que freqüentavam esta creche. Contudo, estudos controlados usando técnicas de epidemiologia molecular são necessários para definir mais precisamente o papel da creche na disseminação do CMV. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1996-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/29356Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 No. 3 (1996); 165-169 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 Núm. 3 (1996); 165-169 Revista do Instituto de Medicina Tropical de São Paulo; v. 38 n. 3 (1996); 165-169 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/29356/31213Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessMello, Ana L. R. deFerreira, Elizabeth C.Vilas Boas, Lucy S.Pannuti, Claudio S.2012-07-02T01:43:25Zoai:revistas.usp.br:article/29356Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:06.287520Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Infecção por citomegalovírus em creche do município de São Paulo Cytomegalovirus infection in a day-care center in the municipality of São Paulo |
title |
Infecção por citomegalovírus em creche do município de São Paulo |
spellingShingle |
Infecção por citomegalovírus em creche do município de São Paulo Mello, Ana L. R. de Cytomegalovirus Day-Care center Epidemiology |
title_short |
Infecção por citomegalovírus em creche do município de São Paulo |
title_full |
Infecção por citomegalovírus em creche do município de São Paulo |
title_fullStr |
Infecção por citomegalovírus em creche do município de São Paulo |
title_full_unstemmed |
Infecção por citomegalovírus em creche do município de São Paulo |
title_sort |
Infecção por citomegalovírus em creche do município de São Paulo |
author |
Mello, Ana L. R. de |
author_facet |
Mello, Ana L. R. de Ferreira, Elizabeth C. Vilas Boas, Lucy S. Pannuti, Claudio S. |
author_role |
author |
author2 |
Ferreira, Elizabeth C. Vilas Boas, Lucy S. Pannuti, Claudio S. |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Mello, Ana L. R. de Ferreira, Elizabeth C. Vilas Boas, Lucy S. Pannuti, Claudio S. |
dc.subject.por.fl_str_mv |
Cytomegalovirus Day-Care center Epidemiology |
topic |
Cytomegalovirus Day-Care center Epidemiology |
description |
The prevalence of antibodies against cytomegalovirus (CMV) and the incidence of CMV infection were tested in 98 children aged 5 to 36 months who attended the day-care center of a University hospital in São Paulo. At the beginning of the study the overall prevalence of anti-CMV IgG antibodies was 44% (43/98). Saliva and/or urine samples were obtained from 38 of the 43 children that were seropositive at the beginning of the study for isolation of the virus, and 52.6% of these children were found to excrete CMV in one of the two materials. Among the 37 children that were initially seronegative from whom it was possible to obtain a new blood sample 6 to 12 months later, 22 (59.5%) presented seroconversion. The rate of viral excretion through urine or saliva from the children that seroconverted was 50%. These results indicate that CMV infection is frequent and occurs early among the children who attend this day-care center. However, controlled studies using molecular epidemiology techniques are needed to define more precisely the role of day-care centers in CMV dissemination. |
publishDate |
1996 |
dc.date.none.fl_str_mv |
1996-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/29356 |
url |
https://www.revistas.usp.br/rimtsp/article/view/29356 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/29356/31213 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 No. 3 (1996); 165-169 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 Núm. 3 (1996); 165-169 Revista do Instituto de Medicina Tropical de São Paulo; v. 38 n. 3 (1996); 165-169 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
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