A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/112737 |
Resumo: | Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In this study, we estimated the number of possible leptospirosis cases among dengue-like cases that were reported during 2008, 2010, and 2012 in the city of Fortaleza, northeast Brazil. Patients were evaluated for dengue and leptospirosis using immunoenzymatic tests for IgM antibodies that were specific to each pathogen. Among the suspected cases of dengue that resulted as negative in laboratory tests, 10.8% (2008), 19.2% (2010), and 30.8% (2012) were confirmed to be leptospirosis. Considering the cases reported by the surveillance authority as dengue that were subsequently discarded based on the laboratory test results, we estimate that the number of actual leptospirosis cases may be 26 to 49 times higher than those diagnosed and reported by the Health Services. Furthermore, we believe that approximately 20% of dengue-like cases may be leptospirosis cases in areas where the two diseases are endemic. |
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A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? Uma nova possibilidade de vigilância: identificamos todos os casos de leptospirose? Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In this study, we estimated the number of possible leptospirosis cases among dengue-like cases that were reported during 2008, 2010, and 2012 in the city of Fortaleza, northeast Brazil. Patients were evaluated for dengue and leptospirosis using immunoenzymatic tests for IgM antibodies that were specific to each pathogen. Among the suspected cases of dengue that resulted as negative in laboratory tests, 10.8% (2008), 19.2% (2010), and 30.8% (2012) were confirmed to be leptospirosis. Considering the cases reported by the surveillance authority as dengue that were subsequently discarded based on the laboratory test results, we estimate that the number of actual leptospirosis cases may be 26 to 49 times higher than those diagnosed and reported by the Health Services. Furthermore, we believe that approximately 20% of dengue-like cases may be leptospirosis cases in areas where the two diseases are endemic. A leptospirose é doença febril tipicamente subestimada em todo o mundo, principalmente em áreas que a dengue se apresenta de forma endêmica. Desta forma, há limitações importantes na compreensão do número de casos de leptospirose nessas áreas, o que proporciona maior subnotificação. Neste estudo, apresentamos estimativa de possíveis casos de leptospirose a partir de casos de dengue-símile na cidade de Fortaleza, nordeste do Brasil, durante os anos de 2008, 2010 e 2012. Os pacientes foram investigados para dengue e leptospirose utilizando testes imunoezimáticos para detecção do anticorpo, da classe IgM, específicos para cada patologia. Entre os casos suspeitos de dengue, mas que não apresentaram resultado laboratorial positivo, 10,8%; 19,2% e 30,8% foram confirmados como leptospirose nos anos de 2008, 2010 e 2012; respectivamente. Considerando os casos notificados pela vigilância de dengue e que foram, posteriormente, descartados, baseados nos resultados dos testes laboratoriais, estimamos que o número atual de casos de leptospirose pode ser de 26 a 49 vezes mais do que o detectado e notificado pelos serviços de saúde. Além disso, acreditamos que aproximadamente 20% dos casos de dengue-símile podem ser de leptospirose, em áreas onde as duas doenças ocorram de forma endêmica. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2015-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/112737Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 No. 5 (2015); 443-446Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 Núm. 5 (2015); 443-446Revista do Instituto de Medicina Tropical de São Paulo; v. 57 n. 5 (2015); 443-4461678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/112737/110660Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessFONTES, Raissa MatosCAVALCANTI, Luciano Pamplona de GóesOLIVEIRA, Augusto César AragãoBEZERRA, Laiane Fernanda de MeloGOMES, Almira Maria MonteiroCOLARES, Jeová Keny BaimaLIMA, Danielle Malta2016-03-23T16:28:46Zoai:revistas.usp.br:article/112737Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:35.265648Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? Uma nova possibilidade de vigilância: identificamos todos os casos de leptospirose? |
title |
A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
spellingShingle |
A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? FONTES, Raissa Matos |
title_short |
A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
title_full |
A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
title_fullStr |
A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
title_full_unstemmed |
A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
title_sort |
A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? |
author |
FONTES, Raissa Matos |
author_facet |
FONTES, Raissa Matos CAVALCANTI, Luciano Pamplona de Góes OLIVEIRA, Augusto César Aragão BEZERRA, Laiane Fernanda de Melo GOMES, Almira Maria Monteiro COLARES, Jeová Keny Baima LIMA, Danielle Malta |
author_role |
author |
author2 |
CAVALCANTI, Luciano Pamplona de Góes OLIVEIRA, Augusto César Aragão BEZERRA, Laiane Fernanda de Melo GOMES, Almira Maria Monteiro COLARES, Jeová Keny Baima LIMA, Danielle Malta |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
FONTES, Raissa Matos CAVALCANTI, Luciano Pamplona de Góes OLIVEIRA, Augusto César Aragão BEZERRA, Laiane Fernanda de Melo GOMES, Almira Maria Monteiro COLARES, Jeová Keny Baima LIMA, Danielle Malta |
description |
Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In this study, we estimated the number of possible leptospirosis cases among dengue-like cases that were reported during 2008, 2010, and 2012 in the city of Fortaleza, northeast Brazil. Patients were evaluated for dengue and leptospirosis using immunoenzymatic tests for IgM antibodies that were specific to each pathogen. Among the suspected cases of dengue that resulted as negative in laboratory tests, 10.8% (2008), 19.2% (2010), and 30.8% (2012) were confirmed to be leptospirosis. Considering the cases reported by the surveillance authority as dengue that were subsequently discarded based on the laboratory test results, we estimate that the number of actual leptospirosis cases may be 26 to 49 times higher than those diagnosed and reported by the Health Services. Furthermore, we believe that approximately 20% of dengue-like cases may be leptospirosis cases in areas where the two diseases are endemic. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/112737 |
url |
https://www.revistas.usp.br/rimtsp/article/view/112737 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/112737/110660 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 No. 5 (2015); 443-446 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 Núm. 5 (2015); 443-446 Revista do Instituto de Medicina Tropical de São Paulo; v. 57 n. 5 (2015); 443-446 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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1798951651278585856 |