A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?

Detalhes bibliográficos
Autor(a) principal: FONTES, Raissa Matos
Data de Publicação: 2015
Outros Autores: CAVALCANTI, Luciano Pamplona de Góes, OLIVEIRA, Augusto César Aragão, BEZERRA, Laiane Fernanda de Melo, GOMES, Almira Maria Monteiro, COLARES, Jeová Keny Baima, LIMA, Danielle Malta
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/112737
Resumo: Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In this study, we estimated the number of possible leptospirosis cases among dengue-like cases that were reported during 2008, 2010, and 2012 in the city of Fortaleza, northeast Brazil. Patients were evaluated for dengue and leptospirosis using immunoenzymatic tests for IgM antibodies that were specific to each pathogen. Among the suspected cases of dengue that resulted as negative in laboratory tests, 10.8% (2008), 19.2% (2010), and 30.8% (2012) were confirmed to be leptospirosis. Considering the cases reported by the surveillance authority as dengue that were subsequently discarded based on the laboratory test results, we estimate that the number of actual leptospirosis cases may be 26 to 49 times higher than those diagnosed and reported by the Health Services. Furthermore, we believe that approximately 20% of dengue-like cases may be leptospirosis cases in areas where the two diseases are endemic.
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spelling A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS? Uma nova possibilidade de vigilância: identificamos todos os casos de leptospirose? Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In this study, we estimated the number of possible leptospirosis cases among dengue-like cases that were reported during 2008, 2010, and 2012 in the city of Fortaleza, northeast Brazil. Patients were evaluated for dengue and leptospirosis using immunoenzymatic tests for IgM antibodies that were specific to each pathogen. Among the suspected cases of dengue that resulted as negative in laboratory tests, 10.8% (2008), 19.2% (2010), and 30.8% (2012) were confirmed to be leptospirosis. Considering the cases reported by the surveillance authority as dengue that were subsequently discarded based on the laboratory test results, we estimate that the number of actual leptospirosis cases may be 26 to 49 times higher than those diagnosed and reported by the Health Services. Furthermore, we believe that approximately 20% of dengue-like cases may be leptospirosis cases in areas where the two diseases are endemic. A leptospirose é doença febril tipicamente subestimada em todo o mundo, principalmente em áreas que a dengue se apresenta de forma endêmica. Desta forma, há limitações importantes na compreensão do número de casos de leptospirose nessas áreas, o que proporciona maior subnotificação. Neste estudo, apresentamos estimativa de possíveis casos de leptospirose a partir de casos de dengue-símile na cidade de Fortaleza, nordeste do Brasil, durante os anos de 2008, 2010 e 2012. Os pacientes foram investigados para dengue e leptospirose utilizando testes imunoezimáticos para detecção do anticorpo, da classe IgM, específicos para cada patologia. Entre os casos suspeitos de dengue, mas que não apresentaram resultado laboratorial positivo, 10,8%; 19,2% e 30,8% foram confirmados como leptospirose nos anos de 2008, 2010 e 2012; respectivamente. Considerando os casos notificados pela vigilância de dengue e que foram, posteriormente, descartados, baseados nos resultados dos testes laboratoriais, estimamos que o número atual de casos de leptospirose pode ser de 26 a 49 vezes mais do que o detectado e notificado pelos serviços de saúde. Além disso, acreditamos que aproximadamente 20% dos casos de dengue-símile podem ser de leptospirose, em áreas onde as duas doenças ocorram de forma endêmica. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2015-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/112737Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 No. 5 (2015); 443-446Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 Núm. 5 (2015); 443-446Revista do Instituto de Medicina Tropical de São Paulo; v. 57 n. 5 (2015); 443-4461678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/112737/110660Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessFONTES, Raissa MatosCAVALCANTI, Luciano Pamplona de GóesOLIVEIRA, Augusto César AragãoBEZERRA, Laiane Fernanda de MeloGOMES, Almira Maria MonteiroCOLARES, Jeová Keny BaimaLIMA, Danielle Malta2016-03-23T16:28:46Zoai:revistas.usp.br:article/112737Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:35.265648Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
Uma nova possibilidade de vigilância: identificamos todos os casos de leptospirose?
title A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
spellingShingle A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
FONTES, Raissa Matos
title_short A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
title_full A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
title_fullStr A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
title_full_unstemmed A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
title_sort A NEW POSSIBILITY FOR SURVEILLANCE: DO WE IDENTIFY ALL CASES OF LEPTOSPIROSIS?
author FONTES, Raissa Matos
author_facet FONTES, Raissa Matos
CAVALCANTI, Luciano Pamplona de Góes
OLIVEIRA, Augusto César Aragão
BEZERRA, Laiane Fernanda de Melo
GOMES, Almira Maria Monteiro
COLARES, Jeová Keny Baima
LIMA, Danielle Malta
author_role author
author2 CAVALCANTI, Luciano Pamplona de Góes
OLIVEIRA, Augusto César Aragão
BEZERRA, Laiane Fernanda de Melo
GOMES, Almira Maria Monteiro
COLARES, Jeová Keny Baima
LIMA, Danielle Malta
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv FONTES, Raissa Matos
CAVALCANTI, Luciano Pamplona de Góes
OLIVEIRA, Augusto César Aragão
BEZERRA, Laiane Fernanda de Melo
GOMES, Almira Maria Monteiro
COLARES, Jeová Keny Baima
LIMA, Danielle Malta
description Leptospirosis is a febrile disease with a typically underestimated global incidence, especially in regions where dengue is endemic. Therefore, it is difficult to accurately determine the number of leptospirosis cases in these areas, which contributes to significant under-reporting this disease. In this study, we estimated the number of possible leptospirosis cases among dengue-like cases that were reported during 2008, 2010, and 2012 in the city of Fortaleza, northeast Brazil. Patients were evaluated for dengue and leptospirosis using immunoenzymatic tests for IgM antibodies that were specific to each pathogen. Among the suspected cases of dengue that resulted as negative in laboratory tests, 10.8% (2008), 19.2% (2010), and 30.8% (2012) were confirmed to be leptospirosis. Considering the cases reported by the surveillance authority as dengue that were subsequently discarded based on the laboratory test results, we estimate that the number of actual leptospirosis cases may be 26 to 49 times higher than those diagnosed and reported by the Health Services. Furthermore, we believe that approximately 20% of dengue-like cases may be leptospirosis cases in areas where the two diseases are endemic.
publishDate 2015
dc.date.none.fl_str_mv 2015-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/112737
url https://www.revistas.usp.br/rimtsp/article/view/112737
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/112737/110660
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 No. 5 (2015); 443-446
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 57 Núm. 5 (2015); 443-446
Revista do Instituto de Medicina Tropical de São Paulo; v. 57 n. 5 (2015); 443-446
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
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reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
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