Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/169540 |
Resumo: | In experimental infection with Strongyloides venezuelensis, the acute and recovery phases can be distinguished, unlike human infections caused by Strongyloides stercoralis. The objective of this study was to evaluate the production of anti-Strongyloides IgG antibodies and the recognition of immunogenic protein bands during the acute and the recovery phases in rats experimentally infected with S. venezuelensis. Rats were infected subcutaneously with 400 or 4,000 S. venezuelensis infective larvae. The acute phase was characterized by elimination of a large number of eggs in the faeces on days 6-14 post infection; the recovery phase was characterized by the resolution of the infection between days 30 and 35 post infection. Differences in IgG levels were observed in the acute and the recovery phases. Different antigenic fractions were recognized in both phases of infection. It is concluded that proteins within the 30-40 kDa range are immunoreactive markers for both the acute and the recovery phases in rats experimentally infected with S. venezuelensis, particularly using membrane antigen. |
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Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensisStrongyloides venezuelensisAcute and recovery phases30-40 kDa, IgGIn experimental infection with Strongyloides venezuelensis, the acute and recovery phases can be distinguished, unlike human infections caused by Strongyloides stercoralis. The objective of this study was to evaluate the production of anti-Strongyloides IgG antibodies and the recognition of immunogenic protein bands during the acute and the recovery phases in rats experimentally infected with S. venezuelensis. Rats were infected subcutaneously with 400 or 4,000 S. venezuelensis infective larvae. The acute phase was characterized by elimination of a large number of eggs in the faeces on days 6-14 post infection; the recovery phase was characterized by the resolution of the infection between days 30 and 35 post infection. Differences in IgG levels were observed in the acute and the recovery phases. Different antigenic fractions were recognized in both phases of infection. It is concluded that proteins within the 30-40 kDa range are immunoreactive markers for both the acute and the recovery phases in rats experimentally infected with S. venezuelensis, particularly using membrane antigen.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2020-05-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/xmlhttps://www.revistas.usp.br/rimtsp/article/view/16954010.1590/S1678-9946202062023Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e23Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e23Revista do Instituto de Medicina Tropical de São Paulo; v. 62 (2020); e231678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/169540/160544https://www.revistas.usp.br/rimtsp/article/view/169540/160545Copyright (c) 2020 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessFonseca, Priscilla Duarte MarquesCorral, Marcelo AndreetaMeisel, Dirce Mary C. LimaLevi, DeboraNascimento, Rafael CorreaCastro‑Borges, WilliamGryschek, RonaldoCosta-Cruz, Julia MariaPaula, Fabiana Martins de2020-10-26T17:39:25Zoai:revistas.usp.br:article/169540Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:52.123984Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis |
title |
Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis |
spellingShingle |
Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis Fonseca, Priscilla Duarte Marques Strongyloides venezuelensis Acute and recovery phases 30-40 kDa, IgG |
title_short |
Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis |
title_full |
Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis |
title_fullStr |
Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis |
title_full_unstemmed |
Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis |
title_sort |
Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis |
author |
Fonseca, Priscilla Duarte Marques |
author_facet |
Fonseca, Priscilla Duarte Marques Corral, Marcelo Andreeta Meisel, Dirce Mary C. Lima Levi, Debora Nascimento, Rafael Correa Castro‑Borges, William Gryschek, Ronaldo Costa-Cruz, Julia Maria Paula, Fabiana Martins de |
author_role |
author |
author2 |
Corral, Marcelo Andreeta Meisel, Dirce Mary C. Lima Levi, Debora Nascimento, Rafael Correa Castro‑Borges, William Gryschek, Ronaldo Costa-Cruz, Julia Maria Paula, Fabiana Martins de |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Fonseca, Priscilla Duarte Marques Corral, Marcelo Andreeta Meisel, Dirce Mary C. Lima Levi, Debora Nascimento, Rafael Correa Castro‑Borges, William Gryschek, Ronaldo Costa-Cruz, Julia Maria Paula, Fabiana Martins de |
dc.subject.por.fl_str_mv |
Strongyloides venezuelensis Acute and recovery phases 30-40 kDa, IgG |
topic |
Strongyloides venezuelensis Acute and recovery phases 30-40 kDa, IgG |
description |
In experimental infection with Strongyloides venezuelensis, the acute and recovery phases can be distinguished, unlike human infections caused by Strongyloides stercoralis. The objective of this study was to evaluate the production of anti-Strongyloides IgG antibodies and the recognition of immunogenic protein bands during the acute and the recovery phases in rats experimentally infected with S. venezuelensis. Rats were infected subcutaneously with 400 or 4,000 S. venezuelensis infective larvae. The acute phase was characterized by elimination of a large number of eggs in the faeces on days 6-14 post infection; the recovery phase was characterized by the resolution of the infection between days 30 and 35 post infection. Differences in IgG levels were observed in the acute and the recovery phases. Different antigenic fractions were recognized in both phases of infection. It is concluded that proteins within the 30-40 kDa range are immunoreactive markers for both the acute and the recovery phases in rats experimentally infected with S. venezuelensis, particularly using membrane antigen. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-05-08 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/169540 10.1590/S1678-9946202062023 |
url |
https://www.revistas.usp.br/rimtsp/article/view/169540 |
identifier_str_mv |
10.1590/S1678-9946202062023 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/169540/160544 https://www.revistas.usp.br/rimtsp/article/view/169540/160545 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2020 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2020 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/xml |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e23 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 62 (2020); e23 Revista do Instituto de Medicina Tropical de São Paulo; v. 62 (2020); e23 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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1798951652681580544 |