Síndrome hemofagocitária associada com hepatite A: relato de caso e revisão da literatura

Detalhes bibliográficos
Autor(a) principal: Tuon, Felipe Francisco
Data de Publicação: 2008
Outros Autores: Gomes, Virginia Soares, Amato, Valdir Sabbaga, Graf, Maria Esther, Fonseca, Guilherme Henrique Hencklain, Lazari, Carolina, Nicodemo, Antonio Carlos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/31165
Resumo: Virus-Associated Hemophagocytic Syndrome (VAHS) is a severe hematological disorder related to some viral infections. It is an illness characterized by persistent fever, pancytopenia, splenomegaly, hyperferritinemia and, the most important, hemophagocytosis observed in the bone marrow, liver and/or lymph nodes. VAHS associated with hepatitis A virus infection is rarely described, despite the high incidence of this viral infection in the population in general. There is no consensus in the literature regarding the optimal treatment of VAHS. In this article the clinical features, presumed pathogenesis, diagnostic criteria and treatment of VAHS are discussed, including description of cases of VAHS related to hepatitis A virus infection found in the medical literature.
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spelling Síndrome hemofagocitária associada com hepatite A: relato de caso e revisão da literatura Hemophagocytic syndrome associated with hepatitis A: case report and literature review Hemophagocytic syndromeHemophagocytosisViral-associated hemophagocytic syndromeHepatitis A virusIntravenous immunoglobulinThrombocytopeniaPancytopenia Virus-Associated Hemophagocytic Syndrome (VAHS) is a severe hematological disorder related to some viral infections. It is an illness characterized by persistent fever, pancytopenia, splenomegaly, hyperferritinemia and, the most important, hemophagocytosis observed in the bone marrow, liver and/or lymph nodes. VAHS associated with hepatitis A virus infection is rarely described, despite the high incidence of this viral infection in the population in general. There is no consensus in the literature regarding the optimal treatment of VAHS. In this article the clinical features, presumed pathogenesis, diagnostic criteria and treatment of VAHS are discussed, including description of cases of VAHS related to hepatitis A virus infection found in the medical literature. A síndrome hemofagocitária associada a vírus é uma doença hematológica grave relacionada com algumas síndromes virais. É doença caracterizada por febre persistente, pancitopenia, esplenomegalia, hiperferritinemia e hemofagocitose na medula óssea, fígado e/ou linfonodos. A síndrome hemofagocitária associada ao vírus da hepatite A é raramente descrita, apesar da alta incidência desta infecção viral na população como um todo. Não existem consensos na literatura a respeito do tratamento desta morbidade. Neste artigo, os aspectos clínicos, patogênese, critérios diagnósticos e tratamento da síndrome hemofagocitária associada a vírus, incluindo a descrição de casos publicados da síndrome associada ao vírus da hepatite A. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2008-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/31165Revista do Instituto de Medicina Tropical de São Paulo; Vol. 50 No. 2 (2008); 123-127 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 50 Núm. 2 (2008); 123-127 Revista do Instituto de Medicina Tropical de São Paulo; v. 50 n. 2 (2008); 123-127 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/31165/33049Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessTuon, Felipe FranciscoGomes, Virginia SoaresAmato, Valdir SabbagaGraf, Maria EstherFonseca, Guilherme Henrique HencklainLazari, CarolinaNicodemo, Antonio Carlos2012-07-07T19:08:37Zoai:revistas.usp.br:article/31165Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:51.385558Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Síndrome hemofagocitária associada com hepatite A: relato de caso e revisão da literatura
Hemophagocytic syndrome associated with hepatitis A: case report and literature review
title Síndrome hemofagocitária associada com hepatite A: relato de caso e revisão da literatura
spellingShingle Síndrome hemofagocitária associada com hepatite A: relato de caso e revisão da literatura
Tuon, Felipe Francisco
Hemophagocytic syndrome
Hemophagocytosis
Viral-associated hemophagocytic syndrome
Hepatitis A virus
Intravenous immunoglobulin
Thrombocytopenia
Pancytopenia
title_short Síndrome hemofagocitária associada com hepatite A: relato de caso e revisão da literatura
title_full Síndrome hemofagocitária associada com hepatite A: relato de caso e revisão da literatura
title_fullStr Síndrome hemofagocitária associada com hepatite A: relato de caso e revisão da literatura
title_full_unstemmed Síndrome hemofagocitária associada com hepatite A: relato de caso e revisão da literatura
title_sort Síndrome hemofagocitária associada com hepatite A: relato de caso e revisão da literatura
author Tuon, Felipe Francisco
author_facet Tuon, Felipe Francisco
Gomes, Virginia Soares
Amato, Valdir Sabbaga
Graf, Maria Esther
Fonseca, Guilherme Henrique Hencklain
Lazari, Carolina
Nicodemo, Antonio Carlos
author_role author
author2 Gomes, Virginia Soares
Amato, Valdir Sabbaga
Graf, Maria Esther
Fonseca, Guilherme Henrique Hencklain
Lazari, Carolina
Nicodemo, Antonio Carlos
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Tuon, Felipe Francisco
Gomes, Virginia Soares
Amato, Valdir Sabbaga
Graf, Maria Esther
Fonseca, Guilherme Henrique Hencklain
Lazari, Carolina
Nicodemo, Antonio Carlos
dc.subject.por.fl_str_mv Hemophagocytic syndrome
Hemophagocytosis
Viral-associated hemophagocytic syndrome
Hepatitis A virus
Intravenous immunoglobulin
Thrombocytopenia
Pancytopenia
topic Hemophagocytic syndrome
Hemophagocytosis
Viral-associated hemophagocytic syndrome
Hepatitis A virus
Intravenous immunoglobulin
Thrombocytopenia
Pancytopenia
description Virus-Associated Hemophagocytic Syndrome (VAHS) is a severe hematological disorder related to some viral infections. It is an illness characterized by persistent fever, pancytopenia, splenomegaly, hyperferritinemia and, the most important, hemophagocytosis observed in the bone marrow, liver and/or lymph nodes. VAHS associated with hepatitis A virus infection is rarely described, despite the high incidence of this viral infection in the population in general. There is no consensus in the literature regarding the optimal treatment of VAHS. In this article the clinical features, presumed pathogenesis, diagnostic criteria and treatment of VAHS are discussed, including description of cases of VAHS related to hepatitis A virus infection found in the medical literature.
publishDate 2008
dc.date.none.fl_str_mv 2008-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/31165
url https://www.revistas.usp.br/rimtsp/article/view/31165
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/31165/33049
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 50 No. 2 (2008); 123-127
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 50 Núm. 2 (2008); 123-127
Revista do Instituto de Medicina Tropical de São Paulo; v. 50 n. 2 (2008); 123-127
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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